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Oral Metabolic Drug Acquired by Novo Nordisk Continues to Show Concerning Neuro Side Effects

MedCity News

Novo Nordisks monlunabant showed signs of neuropsychiatric side effects in a mid-stage diabetic kidney disease study, despite a drug design intended to favor hitting its target receptor in peripheral tissues rather than the brain. Neuro effects were also reported last year in a Phase 2 test of this pill in obesity.

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Side Effects are Limiting GLP-1 Drug Efficacy: How Can Personalization Offer a Solution?

MedCity News

By integrating digitization and machine learning, there is an opportunity to deliver personalized care to all patients and scale precision dosing with minimal physician involvement, maximizing the effectiveness and accessibility of these drugs. The post Side Effects are Limiting GLP-1 Drug Efficacy: How Can Personalization Offer a Solution?

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Lilly touts new Kisunla regimen that reduces side effects

pharmaphorum

Eli Lilly says a new starting dose regimen for its Alzheimer's disease therapy Kisunla reduces the risk of side effects that have stood in the way of approvals and reimbursement decisions for drugs in its class.Simply shifting one vial of the anti-amyloid antibody from the first infusion to the third infusion of the titration phase of dosing – the (..)

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UK regulators warn of ocular side effects after treatment with Sanofi's Dupixent

Fierce Pharma

UK regulators warn of ocular side effects after treatment with Sanofi's Dupixent. Wed, 11/30/2022 - 10:55.

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Drug side effects should be easier to understand

World of DTC Marketing

According to the AMA one of the key reasons for non-adherence is that patients may be frightened of potential side effects. Additionally, patients report not taking their medication because they may have witnessed side effects experienced by a friend or family member who was taking the same or similar medication.

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Serious Side Effect Sidelines Gene-Edited Sickle Cell Therapy from Graphite Bio

MedCity News

Graphite Bio voluntarily paused a Phase 1/2 test of its gene-edited therapy for sickle cell disease after the first patient in the study developed a serious blood complication. The setback will also delay plans to reach the clinic with another genetic medicine in its pipeline.

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Seeking full approval in Alzheimer's, Eisai dives into prominent Leqembi side effect

Fierce Pharma

Seeking full approval in Alzheimer's, Eisai dives into prominent Leqembi side effect fkansteiner Fri, 03/31/2023 - 11:30