European Pharmaceutical Review

FEBRUARY 27, 2024

The Chief Executive of the Medicines and Healthcare products Regulatory Agency (MHRA), Dame June Raine, will step down in the Autumn following five years in the role. Her previous role in the agency was as Director of Vigilance and Risk Management of Medicines.

Safety 111

Safety Pharmacology Medicine Education 111

European Pharmaceutical Review

MAY 29, 2024

“For more than two decades, omalizumab, a blockbuster monoclonal antibody anti-IgE, has revolutionised the management of chronic immune-mediated inflammatory diseases,” commented Professor Marcus Maurer , Professor of Dermatology and Allergy, Co-Director for the Fraunhofer Site for Immunology and Allergology of the Fraunhofer Translational Medicine (..)

Food and Drug Administration 98

Food and Drug Administration Pharmacology FDA Food 98

European Pharmaceutical Review

JULY 4, 2024

2 Approach taken by regulators in the UK The Medicines and Healthcare products Regulatory Agency regulates herbal medicines in the UK. Herbal medicines placed on the market since April 2011 must have either a traditional herbal registration (THR) or a Marketing Authorisation (MA). 2012/1916). 2012/1916). 2012/1916). 2012/1916).

Marketing 103

Marketing Food and Drug Administration Medicine Prescription 103

European Pharmaceutical Review

JANUARY 19, 2024

Positive recommendation of talazoparib “is an important advance in expanding treatment options for eligible patients who currently have limited alternative treatments,” Chris Twelves, Director of NIHR Leeds Clinical Research Facility and Professor of Clinical Cancer Pharmacology and Oncology noted.

Pharmacology 98

Pharmacology Patients Pharmaceutical Medicine 98

Pharma Leaders

APRIL 17, 2023

Abliva is a clinical-stage company developing medicines to treat rare and severe primary mitochondrial diseases. NV354 has indicated to be safe and efficacious in pre-clinical models, with regard to optimal pharmacological properties, including high levels of brain penetration.

FDA 52

FDA Pharmacology Medicine Leads 52

Impetus Digital

AUGUST 2, 2024

Personalized Medicine AI can help develop precision medicine by analyzing patient data , including demographic, clinical, and genetic information, as well as information about their metabolism and microbes, environmental exposures, and lifestyle factors, to predict how different patients will respond to various therapies.

Pharma 95

Pharma Manufacturing Medicine Marketing 95

Pharmaceutical Technology

APRIL 25, 2023

4DMT will be responsible for licence payments to the University of Pennsylvania, where the Perelman School of Medicine’s pharmacology professor, Dr Wenchao Song, jointly invented and developed the sCFH technology. The firm will also receive single-digit royalties on net sales.

Pharmacology 52

Pharmacology Engineering Sales Medicine 52

pharmaphorum

NOVEMBER 1, 2022

Investigating the next generation of genetic medicine through RNA based therapies. RNA therapeutics is a rapidly expanding industry with increasingly growing potential for immunotherapy, personalised medicines, and treatment of genetic, infectious, and chronic diseases. Heads of Translational Medicine. Website: [link].

Medicine 52

Medicine Pharmacology Networking Pharma 52

pharmaphorum

DECEMBER 15, 2022

Currently, the only treatment option for people with IPF fibrosis who have an FVC above 80% predicted is supportive care, so the new guidance takes Ofev into new territory for pharmacological treatment of the progressive lung disease, characterised by damage and scarring to the tissue surrounding the small airways in the lungs.

Pharmacology 104

Pharmacology Doctors Patients Medicine 104

European Pharmaceutical Review

MAY 2, 2023

3 With greater scientific understanding of cancer, the industry has made significant progress in developing innovative medicines to help patients. However, access to these medicines is not close to meeting patient demand, creating inequalities in the health prospects of those diagnosed with cancer. 1,2 In the EU, an estimated 2.7

Patients 105

Patients Medicine Marketing Medical 105

European Pharmaceutical Review

MARCH 11, 2024

HIV treatment and prevention are at an inflection point after years of continuously improving the standard of care of once-daily oral medicines. Our industry is on the cusp of the next wave of medicines that will guide the coming decade of HIV care, making HIV a smaller part of people’s lives. 3 But that paradigm is rapidly changing.

Medicine 98

Medicine Pharmacology Healthcare Healthcare 98

Pharmaceutical Technology

SEPTEMBER 14, 2022

Victoza, Copaxone, Lupron, Zoladex, Sandostatin, and Somatuline are some of the popularly marketed peptide API therapeutic drugs while more than 600 peptide-based pharmacological leads are being investigated worldwide, across various phases of development.

Leads 52

Leads Marketing Pharmacology Retail 52

pharmaphorum

JANUARY 4, 2023

It looks like Astellas has been unsuccessful in its attempt to block Pfizer’s generic medicines unit Hospira from launching a copycat version of big-selling pharmacologic stress agent Lexiscan in the US.

Pharmacology 59

Pharmacology Marketing Pharma Competition 59

Legacy MEDSearch

JUNE 15, 2023

Cala , the bioelectronic medicine leader setting a new standard of care for chronic disease, today announced the commercial launch of its next generation system: the Cala kIQ System, the first and only FDA-cleared wearable device that delivers effective therapy for action hand tremor relief in people with essential tremor and Parkinson’s disease.

Patients 98

Patients Recruitment Pharmacology Management 98

PM360

MARCH 19, 2024

Kris Carr said that personalized medicine must go beyond pharmacological interventions, “We aren’t statistics,” Carr said, “we are whole people, with whole lives, who deserve complete care.” That sense of personal agency and control in the face of an uncertain diagnosis is critical to maintaining hope.

Healthcare 52

Healthcare Healthcare Pharmacology Medicine 52

Pharmaceutical Technology

NOVEMBER 3, 2022

Cardiovascular medicines were ranked as the sixth most affected drug class by shortages, as per a 2019 European Association of Hospital Pharmacists (EAHP) survey, says the organisation’s director of finance, Nenad Miljkovi?. There needs to be more investment into local production to improve the availability of these medicines, says Page.

Medicine 111

Medicine Manufacturing Pharmacology Healthcare 111

European Pharmaceutical Review

JULY 27, 2023

Pharmacological therapies mainly address symptoms and unfortunately a significant number of patients do not respond adequately, progressing to congestive heart failure and eventually needing a heart transplant. Frontiers in Pharmacology. Key success factors for Regenerative Medicine in acquired heart diseases. BMC Cancer.

Pharmacology 98

Pharmacology Manufacturing Leads Patients 98

Pharmaceutical Technology

MARCH 17, 2023

Companies are testing the use of digital platforms along with pharmacological treatments. But while appealing, the prospects of developing a merged approach that combines both digital and pharmacological therapeutics remain challenging.

Prescription 111

Prescription Pharmacology Medical Pharma 111

pharmaphorum

SEPTEMBER 26, 2022

Astellas has won a reprieve in its attempt to stop Pfizer’s generic medicines unit Hospira launching a copycat version of its pharmacologic stress agent Lexiscan in the US – but only for a couple of weeks.

Pharmacology 52

Pharmacology FDA Marketing Pharma 52

Contrarian Sales Techniques

FEBRUARY 25, 2023

During my pharmacology class, I learned that there are no safe drugs, only safe patients. This highlights the importance of taking an individualized approach to medicine and considering a patient's unique medical history, current health status, and other relevant factors when prescribing medication.

Side effects 52

Side effects Medical sales reps Insurance Pharmacology 52

European Pharmaceutical Review

JULY 25, 2024

This progress underscores the potential of gene therapy to revolutionise medicine by addressing the root causes of genetic disorders. Palframan received his BSc in pharmacology at King’s College London and his PhD in immunology at Imperial College London. What could be the next major disruptor in the field?

Pharmacology 52

Pharmacology Manufacturing Medicine Training 52

European Pharmaceutical Review

OCTOBER 19, 2022

Evergreening of patents is the process of patenting post-approval or secondary changes to approved medicinal products. Biopharmaceutical Research & Development: The Process Behind New Medicines. Patent Protection of Pharmacologically Active Metabolites: Theoretical and Technological Analysis on the Jurisprudence of Four Regions.

Food and Drug Administration 96

Food and Drug Administration Pharmaceutical products Pharmaceutical FDA 96

Medgadget

NOVEMBER 24, 2022

The basis for many pharmacological interactions between drugs and cells, and indeed many physiological or pathological interactions involving biological signaling molecules, involves a molecule, termed a ligand, binding to a receptor that is typically present on the cell membrane.

Pharmacology 88

Pharmacology Engineering Medicine 88

pharmaphorum

JANUARY 16, 2023

Across swathes of primary care, pharmacological innovation has stalled; the last new antihypertensive class was introduced in 2007 and new antibiotics have trickled in at a dangerously slow pace. And all are predominantly prevented or treated with medicines that are decades old.

FDA 88

FDA Healthcare Healthcare Medicine 88

PM360

NOVEMBER 29, 2022

Food and Drug Administration (FDA) or European Medicines Agency (EMA). Typically, a drug label refers to any information provided with prescription drugs, as requested by regulators such as the U.S.

Food and Drug Administration 98

Food and Drug Administration Competition Safety Pharmacology 98

MedCity News

JUNE 16, 2023

While not a panacea, these technologies can be part of a comprehensive set of solutions that help close the gap of inequity in medicine and drug development.

Pharma 112

Pharma Food and Drug Administration Recruitment Patients 112

European Pharmaceutical Review

JULY 18, 2024

The potential to target more than one tumour antigen is interesting, as are the possible advantages for the patients receiving these investigational medicines. This covers nonclinical drug safety, translational and clinical pharmacology, drug metabolism and pharmacokinetics (DMPK) and pharmacometrics.

Food and Drug Administration 59

Food and Drug Administration Engineering Pharmacology Side effects 59

Pharmaceutical Technology

MAY 24, 2023

Several tetrapeptides are pharmacologically active, showing affinity and specificity for multiple receptors in protein-protein signalling. Amgen develops, manufactures, and markets innovative human medicines to treat patients suffering from serious diseases.

Pharmaceutical 52

Pharmaceutical Leads Biopharma Pharmacology 52

pharmaphorum

JANUARY 26, 2023

A 2022 study from the Royal College of Physicians and British Pharmacological Society demonstrated the potential of pharmacogenomics, with scientists identifying the genetic cause behind an individual’s drug response for over forty medicines.

Pharmacology 120

Pharmacology Government Leads Physicians 120

Pharmaceutical Technology

MAY 15, 2023

Pyridine derivatives contain one nitrogen atom in a six-membered aromatic ring and are the most extensively used heterocycles in the field of drug design, due to their promising effect on pharmacological activity, which has led to the discovery of numerous broad-spectrum therapeutic agents.

Pharmaceutical 52

Pharmaceutical Leads Pharmacology Medicine 52

Pharmaceutical Technology

MAY 15, 2023

As molecular targeting peptides, anti-cancer peptides penetrate the plasma membrane, nuclear membrane, and mitochondrial membrane of cancer cells, exerting pharmacological activity through various mechanisms (such as inhibiting DNA synthesis and cell division), thus causing apoptosis of cancer cells.

Leads 52

Leads Biopharma Pharmaceutical Pharma 52

MedReps

JUNE 20, 2022

They’ll also teach you about insurance coverage which is vital to selling any medicine. Pharmaceutical reps use the results of clinical trials to present their medicines fairly and ethically. Medical sales are often mislabeled in the media because of the mistakes of years ago, which involved bribery and misinformation.

Pharmaceutical Sales 76

Pharmaceutical Sales Training Sales Pharmaceutical 76

Pharmaceutical Technology

FEBRUARY 8, 2023

Dr. Lei Xu, chief of the General Medicine Branch 2 in the FDA’s DCEPT, said this is a dilemma as more permanent treatments like gene therapies come to the regulator that often “require substantial evidence of effectiveness from adequate and well controlled clinical studies”.

FDA 105

FDA Patients Pharmacology Pharmaceutical 105

Pharmaceutical Technology

DECEMBER 16, 2022

This year saw great progress towards making new therapeutics for malaria available sooner rather than later, says Karen Barnes, PhD, professor at the University of Cape Town’s Division of Clinical Pharmacology.

Pharmacology 105

Pharmacology Pharma Pharmaceutical Manufacturing 105

Pharmaceutical Technology

FEBRUARY 13, 2023

As well as presenting an acceptable PK profile and demonstrating in-vivo efficacy, it becomes important to show that the candidate drug has a good safety pharmacology margin with an acceptable drug-drug interaction (DDI) profile.

Food and Drug Administration 52

Food and Drug Administration Leads Pharmaceutical Pharmaceutical research 52

Contrarian Sales Techniques

DECEMBER 5, 2023

Another game-changer has been the shift towards personalized medicine. This could mean staying updated with the latest industry trends, enrolling in advanced sales training programs, or pursuing further education in areas like business management or pharmacology. Embracing a mindset of lifelong learning keeps you agile and adaptable.

Pharmaceutical Sales 52

Pharmaceutical Sales Training Sales Pharmaceutical 52

European Pharmaceutical Review

JULY 13, 2023

5 When these medicines are prescribed to patients, we can use feedback from the real-world data that documents clinical outcomes, efficacy measures, patient-reported outcomes, and adverse events. This will lead to a higher proportion of these medicines becoming licensed, benefitting a larger number of patients. 2023 Mar 4;16(3):257-66.

Medical 98

Medical Food and Drug Administration Pharmacology Medicine 98