European Pharmaceutical Review

DECEMBER 11, 2023

mAbs have well-established safety profiles, high specificity and affinity and long half-lives – they have been used in drug development for more than 30 years. Known linkers in the RNA field are used to bond together the two pharmacologically active molecular entities and can be applied to multiple oligonucleotide modalities.

Safety 98

Safety Pharmacology Engineering Medical 98

Pharmaceutical Technology

SEPTEMBER 14, 2022

Victoza, Copaxone, Lupron, Zoladex, Sandostatin, and Somatuline are some of the popularly marketed peptide API therapeutic drugs while more than 600 peptide-based pharmacological leads are being investigated worldwide, across various phases of development.

Leads 40

Leads Marketing Pharmacology Retail 40

Pharmaceutical Technology

FEBRUARY 8, 2023

This document delved into aspects related to manufacturing, preclinical, and clinical trial design for all phases of clinical development. Still, Blank suggested that companies enroll the patient population that is most likely to benefit, because early phase studies contain the most safety risks.

FDA 105

FDA Patients Pharmacology Pharmaceutical 105

European Pharmaceutical Review

JULY 25, 2024

From a sustainability perspective, there is a need to explore how we can lower the cost of production and dose so that gene therapies are more accessible overall, and I feel that manufacturing and delivery innovations are key in the solution to this challenge. What should the industry prioritise to advance the gene therapy field?

Pharmacology 52

Pharmacology Manufacturing Medicine Training 52

Pharmaceutical Representative Training

JUNE 22, 2024

The pharmaceutical industry is one of the most heavily regulated sectors due to the direct impact of its products on public health and safety. Several factors contribute to the stringent regulatory environment: Patient Safety: Ensuring that the pharmaceutical products are safe and effective is a crucial aspect.

Sales 52

Sales Pharmaceutical Ethics Pharmaceutical Sales 52

European Pharmaceutical Review

MAY 2, 2023

By collaborating with several stakeholders and authorities, multiple stages of development can take place concurrently to speed up R&D without compromising safety protocols. Previously, he spent more than 10 years at Roche in multiple positions within medical affairs.

Patients 105

Patients Medicine Marketing Medical 105

Pharmaceutical Technology

FEBRUARY 13, 2023

As well as presenting an acceptable PK profile and demonstrating in-vivo efficacy, it becomes important to show that the candidate drug has a good safety pharmacology margin with an acceptable drug-drug interaction (DDI) profile.

Food and Drug Administration 52

Food and Drug Administration Leads Pharmaceutical Pharmaceutical research 52

European Pharmaceutical Review

JANUARY 13, 2025

The propellant that will be used in Chiesi products is manufactured in the UK, and our global Phase III studies are well underway at five UK sites. Pulmonary Pharmacology & Therapeutics. This step alone is expected to reduce our carbon emissions by up to 90 percent. 2024; 85: 1-9. Internet] The Aerosol Society. Cited 2024August].

Medicine 52

Medicine Pharmaceutical Government Manufacturing 52

Pharmaceutical Technology

MARCH 16, 2023

However, health specialists refute most safety concerns for the use of drug classes as part of gender affirming care, citing years of research and care. With restricted access and reduced prescription of puberty blockers and hormone therapies, the impact on pharmaceutical companies manufacturing these therapies also remains unclear.

Prescription 144

Prescription Ethics Safety Healthcare 144