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Bristol Myers Squibb (BMS) and Cellares have announced a worldwide capacity reservation and supply agreement for the manufacture of CAR T cell therapies. The agreement will see BMS use Cellares’ fully automated cell therapy manufacturing platform for the clinical and commercial-scale manufacturing of select CAR T cell therapies.
AstraZeneca has announced a $300 million investment in a US-based manufacturing facility in Rockville, Maryland, which will focus initially on T-cell therapies for oncology indications. Currently, AstraZeneca’s manufacturing sites in the US focus on producing small molecules and biologics, the company highlighted.
After agreeing to acquire a US-based manufacturing facility and its operations from Novartis, Bristol Myers Squibb (BMS) adds in-house production of viral vectors to its capabilities. This move will support the expansion of the company’s global cell therapy manufacturingnetwork.
It is the company ’s most advanced manufacturing facility to date. The new facility, known as Amgen Ohio, “was designed with the latest innovation and technology to deliver safe, reliable medicines for ‘every patient, every time,'” stated Robert Bradway, Chairman and Chief Executive Officer at Amgen.
After nearly five years of mounting pressures on the American healthcare system, providers and patients are confronting another challenge that shows no signs of slowing down: skyrocketing medical costs. Patients with low incomes are especially vulnerable.
billion parenteral (injectable) manufacturing site in Alzey, Rhineland-Palatinate, Germany. This includes automation and high-speed manufacturing lines. With the planned additional manufacturing facility in Alzey, the company will operate a total of six manufacturing sites in Europe.
Through its investment of approximately £600 million, Takeda plans to build a new manufacturing facility for plasma-derived therapies (PDTs) in Osaka, Japan. This is Takeda’s largest ever investment in manufacturing capacity expansion and will be the largest facility of its kind in Japan.
A new industry survey from the Biotechnology Innovation Organization (BIO) highlights the vulnerability of supply that proposed tariffs would put on medicines, and its impact on patient access. Proposed tariffs on the EU would force half of companies to find new research and manufacturing partners.
A portion of the investment, €125 million, is intended to support greater production capacity at its Latina site, which is a key part of the firm’s worldwide supply chain network, the company stated. Johnson & Johnson Innovative Medicine is planning to invest a total of €580 million in Italy over the next five years.
a groundbreaking respiratory support technology company, announced today that it has begun the manufacturing process for the ALICE CPB (Cardiopulmonary Bypass) device (the “ALICE device”) to undergo the Verification and Validation phase prior to its planned 2023 submission to the U.S. Inspira Technologies OXY B.H.N. and Israel.
Numerous groundbreaking advances have shown these therapies hold potential to revolutionise how we treat, and potentially cure, many conditions, including for patients with underlying genetic or cellular causes of disease that have been difficult to treat with conventionalapproaches.
The European Medicines Agency (EMA) has established the Quality Innovation Expert Group (QIG) to aid innovative approaches for the development, manufacture and quality control (QC) of medicines, including new technologies, digitalisation, novel materials and novel devices for patients in the European Union (EU).
PM360 asked industry experts what it takes to be a patient-first organization and how companies can better ensure they are delivering experiences that meet patients’ expectations. Specifically, we asked them: What is required today for life sciences companies to truly practice a patient-first approach? Matt Flesch.
It pledges to benefit key industry sectors across life sciences including R&D, innovation, manufacturing and medicine. Over the last five years Made Smarter has transformed countless SME manufacturers,” stated Donna Edwards, Director of Made Smarter’s North West adoption programme.
In a highly regulated industry, choosing the right keywords can determine whether your ads reach healthcare professionals, patients, or caregivers effectively. Understanding how patients and healthcare professionals search for medical information is key. For more pharma keyword research strategies, visit Pharma Marketing Network.
And just as a family business thrives on its connection to the community, Chiesi is committed to connecting to the global patient community. We try to have a very long-term orientation because we believe that aligns our objectives very well with the objectives of society and the patients we serve, and it makes us a stable business.”.
Swoop Announces Merge with MyHealthTeam Swoop, an AI-driven healthcare marketing company, has acquired MyHealthTeam, creator of one of the largest patient social networks in the United States. Novo plans to start another study in the first half of 2025 to determine how best to boost patients doses.
WuXi Biologics and InflaRx have entered a manufacturing partnership for advancing Gohibic (vilobelimab) to treat certain critically ill Covid-19 patients. Under the collaboration, WuXi Biologics will be responsible for providing cGMP manufacturing of Gohibic.
The term “patient centricity” has been around for over a decade, and since its first utterance the buzzword has been praised, dissected, criticized, and everything in between. The concept has always been worthwhile, but people within and outside of the industry have wondered whether the industry was truly becoming more patient centric?
The report concluded that the Company’s UroShield device showed a decrease in the number of blockages and infections and an increase in catheter satisfaction in the patients studied. UroShield is available to all NHS clinicians and their patients who need the device with full clinical support, through the NHS supply chain.
Uniting the global supply chain CPHI Barcelona serves as a vital platform for unrivalled networks and access to the global supply chain. The market space offers various benefits, including promotion as a show feature, access to start-up mentors, and a dedicated start-up networking lounge. Manufacturing Excellence 5.
Specifically, an additional four years of funding for the Advanced Therapy Treatment Centre (ATTC) Network is available through the programme. The funding will start with three established Centres, and then across an expanded network, according to Chief Clinical Officer for Cell and Gene Therapy Catapult, Jacqueline Barry.
Takeda has unveiled plans to invest almost $764m (JPY100bn) to construct a new manufacturing facility for plasma-derived therapies (PDTs) in Osaka, Japan. The new facility represents the company’s largest-ever investment in the expansion of manufacturing capacity in the country.
A well-designed and thought-out digital solution, with a considered user experience, can deliver a better service and support HCPs to deliver positive patient outcomes, whilst strengthening relationships between pharma companies and their HCP networks. How can this impact patient care? What is meant by an HCP portal?
ITM Isotope Technologies Munich SE ( ITM )’s manufacturing plant in Neufahrn near Munich will produce the innovative medical isotope for targeted cancer therapies. “Radiopharmaceuticals are an essential new class of anti-cancer drugs that have the potential to improve therapy outcomes and quality of life for many patients.
Under the terms of the agreement, BioNTech will pay $50 million to Autolus, granting the immunotherapy company rights including the option to access Autolus’ commercial and clinical site network, manufacturing capacities in the UK and commercial supply infrastructure.
A report from the Advanced Therapies Treatment Centre (ATTC) Network has highlighted urgent need for rapid change and improvement in the field to maximise patient access to advanced therapies. It was compiled based on expertise gathered at the ATTC Network’s UK Advanced Therapies Adoption Challenge event in October.
Medications and supplies must be handled with the utmost care, often needing to comply with strict temperature regulations and changing demands from patients and providers that vary depending on the country. Add this to infrastructure challenges like cold storage or delays, and it’s no wonder patient needs are not always put first.
Cancer patients critically depend on accurate diagnosis and disease treatment. By reaching cancer cells that have already spread throughout the body, a targeted radiopharmaceutical treatment offers an alternative for patients with advanced cancer when standard lines of treatment, such as chemotherapy, have failed.
Sandoz , a leading antibiotics producer has announced its €50 million investment to increase Europe’s manufacturing capacity of finished dosage form (FDF) penicillin, the most common form of antibiotic worldwide, to enhance global manufacturing capacity of amoxicillin and other major penicillin products.
The exhibition, which will take place from 8-10 October 2024, is being hosted in Milan for the second time in three years in recognition of the massive pharmaceutical ingredients and manufacturing industry in the region. “We expect a large international attendance and will marry this with local and regional manufacturing insights.”
Within the 14-page document , published by an EMA special task force, are 10 recommendations of best practices that “marketing authorisation holders, wholesalers, distributors, and manufacturers can consider adopting to ensure continuity of medicinal product supply and reduce the impact of shortages”.
tariffstargeting imports from key manufacturing hubs like China, Mexico, and Canadais set to introduce new challenges that will reshape the landscape of medical device sales and manufacturing in 2025. based manufacturers relying on imported parts. A core objective of these tariffs is to bring more manufacturing back to the U.S.,
The investment is part of the company’s global effort to implement the most innovative technologies and most sustainable processes at its manufacturing sites. They are used for the treatment of patients with complex diseases, such as primary or acquired immunodeficiencies, or rare diseases like hereditary angioedema and bleeding disorders.
By remaining compliant, medicines are manufactured in line with their pre-defined and approved specifications, in order to ensure the delivery of safe and effective products to consumers. So, with mandates in place, how do manufacturing facilities meet these compliance goals? Cybersecurity and non-conformance.
Healthcare professionals are also catching up to the patient group, which has long been engaged on social media. It can be applied to comprehend patient difficulties and spot chances for clinical intervention. Patient and healthcare professionals anticipate personalized, communication based on value.
These advancements can enhance drug solubility and bioavailability, improve the speed to clinical trials, reduce environmental impact, and increase patient access to treatments. This uncovers opportunities to implement green chemistry principles, overhaul inefficient manufacturing techniques, and modernize outdated methods.
Johnson & Johnson has been cleared to continue a lawsuit filed last year against drug benefit programme SaveOnSP, which claims it defrauded a payment assistance programme for patients out of “at least $100 million.”
For hundreds of years, we have found myriad uses for microbial enzymes in manufacturing – from food, drink, and household products to a range of industrial applications. Continuing advancements within this field deliver new hope to doctors and patients, transforming disease outcomes for previously incurable indications.
Failing to adhere to prescribed medication regimens is one of the prime reasons for poor patient health outcomes. Pharmaceutical and healthcare companies are working continuously to improve patient adherence, which also impacts disease control and pharmaceutical industry revenues directly. Patient adherence.
ERP systems and drug serialisation As the scale of generating serialising products is minimal, small manufacturers can alter or improve their current Base ERP system and develop an internal serialisation process. This can be measured by success factors of systems that have been successfully implemented and their interactions.”
The ability to modify or introduce genetic material in human cells in such a precise and patient-centered manner clearly constitutes a breakthrough in personalized medicine. Allogeneic therapies begin with healthy donor samples to develop the eventual therapeutic product which can be administered to multiple patients.
From the drug discovery phase to patient care, AI has the potential to enhance almost every stage of the product life cycle. Among others, ML algorithms can predict trial outcomes, write protocols, optimize eligibility criteria, identify and recruit the most suitable candidates for trials, monitor patient health remotely, and analyze data.
As witnessed during the Covid-19 pandemic, when supply chains are disrupted, getting supplies and treatments to patients becomes a major issue. Reaching patients can be difficult if roads are washed away, ships can’t leave ports or planes can’t take off due to volatile weather conditions.
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