Actimed’s ALS candidate wins FDA orphan drug designation
Pharmaceutical Technology
SEPTEMBER 4, 2024
Actimed says S-oxprenolol shares a similar pharmacology to its lead product S-pindolol, which is being studied in cachexia.
Mastering Pharmacology: A Game-Changer for Pharma Sales Reps Communicating with HCPs
Pharmaceutical Representative Training
JANUARY 8, 2025
Pharmacology is one of the most fundamental aspects of medication therapy. 1] How can mastering pharmacology give sales reps a competitive advantage when meeting with prospective HCPs? Due to limited knowledge of pharmacology, the sales rep failed to properly communicate and was unable to address the physicians concerns.
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New analysis sets stage for improved UK clinical trials
European Pharmaceutical Review
APRIL 10, 2025
By working together with patients, the NHS, industry, and researchers across the life sciences ecosystem to identify and maximise these opportunities, we can ensure [UK] clinical trials are faster, fairer, and more inclusive” This analysis shows clearly where the UK is leading and where we need to work with our stakeholders to go further.
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Alzheimer’s drug requires strengthened pharmacovigilance approach
European Pharmaceutical Review
MARCH 7, 2025
A paper published by the Drug Safety Research Unit (DSRU) in the British Journal for Clinical Pharmacology , has asserted the need for ongoing assessment of the safety and effectiveness of the Alzheimers drug lecanemab in the real-world clinical setting.
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Can GLP-1 obesity therapy restore NK cell function?
European Pharmaceutical Review
MAY 9, 2023
NK cell functionality was restored in participants following gold-standard pharmacological obesity GLP-1 analogue treatment, according to a study published in Obesity. This may contribute to the benefits reported with these medications in people with obesity, the data showed.
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Leading Nephrologist Discusses Importance of Pharmacist Role In Kidney Care for ASN Kidney Week
Pharmacy Times
NOVEMBER 1, 2022
3-6) by learning about the pharmacological role of kidney care from the president of the American Society of Nephrology. Pharmacy Times is gearing up for Kidney Week (Nov.
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New radiopharmaceutical laboratory opens in Germany
European Pharmaceutical Review
MARCH 6, 2024
The facility will also have capacity to conduct non-clinical pharmacology studies for detailed characterisation of its first-in-class development candidates, according to Ariceum.
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NICE to update endometriosis guidelines to improve diagnosis and surgical management
Pharmaceutical Technology
NOVEMBER 17, 2022
This delay in diagnosis ultimately leads to disease progression and associated complications, such as chronic pelvic pain and infertility, which greatly affects the patients’ quality of life. As a result, women wait eight years on average for a diagnosis after initial symptom onset, a figure that has not changed in a decade.
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Tackling the complex development landscape of pain medicines
European Pharmaceutical Review
JANUARY 11, 2024
The current medications (opioid and non-opioid) often force the patients to make an unfortunate choice between efficacy and debilitating side effects, leading to a cycling through multiple different therapies and suboptimal treatment response. The present unmet needs within chronic pain are not met with opioid therapies. Pain and Therapy.
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Leading API biologics (protein and peptide) companies in contract marketing
Pharmaceutical Technology
SEPTEMBER 14, 2022
Victoza, Copaxone, Lupron, Zoladex, Sandostatin, and Somatuline are some of the popularly marketed peptide API therapeutic drugs while more than 600 peptide-based pharmacological leads are being investigated worldwide, across various phases of development. Discover the top API protein and peptide companies in contract marketing.
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The future of medical cannabis development in Europe
European Pharmaceutical Review
JULY 13, 2023
This could lead to significant research waste. This will lead to a higher proportion of these medicines becoming licensed, benefitting a larger number of patients. He leads the pre-clinical and clinical medical cannabis research programmes in Europe and is responsible for the cannabis clinic rollout across the continent.
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Microbial burden assessment of solid pharmaceutical products
European Pharmaceutical Review
APRIL 19, 2024
The “accurate, precise, and robust” data obtained via the dew point chilled mirror method, means it is an “outstanding” approach for quantifying water activity status in tablets and capsules, according to a paper published in RPS Pharmacy and Pharmacology Reports.
NICE recommends innovative breast cancer drug
European Pharmaceutical Review
JANUARY 19, 2024
Positive recommendation of talazoparib “is an important advance in expanding treatment options for eligible patients who currently have limited alternative treatments,” Chris Twelves, Director of NIHR Leeds Clinical Research Facility and Professor of Clinical Cancer Pharmacology and Oncology noted.
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Angion stock falls after agreeing Elicio Therapeutics merger
pharmaphorum
JANUARY 17, 2023
Angion Biomedica ended 2022 in the midst of a strategic review after its lead drug for kidney diseases flamed out, and it has now charted a path forward – a reverse merger with clinical-stage biotech Elicio Therapeutics.
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Handling HPAPIs safely – what does it take?
European Pharmaceutical Review
MARCH 9, 2023
1 These substances “are pharmacologically and biologically active at low doses,” Dr Kishore Hotha, Global Head of Analytical Research & Development at Veranova, explained. ” Highly potent APIs are pharmacologically and biologically active compounds at low doses.
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Chiesi joins with Aptar on digital platform for respiratory patients
pharmaphorum
OCTOBER 19, 2022
It will combine the pharmacological and behavioural aspects of managing respiratory diseases, according to the partners, such as “adherence monitoring, lung function assessment, reporting symptoms, identifying disease triggers and communication with care teams and health coaches.” billion of its total revenues of €2.4
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Can Hepatitis C drugs reduce symptoms of PTSD?
European Pharmaceutical Review
AUGUST 23, 2022
PTSD is a potentially chronic condition that disrupts lives and can lead to or exacerbate existing health issues such as depression, anxiety, eating disorders, and suicidal thoughts. Many people have PTSD, but there [are] few effective pharmacologic treatments and limited drug development for PTSD,” commented Gradus.
FDA drug dosage optimisation guidelines signal clinical trial reform
Pharmaceutical Technology
FEBRUARY 17, 2023
Most drugs being developed now are more tailored to specific mechanisms of action compared to past drugs, says Dr. Gareth Veal, PhD, a professor of cancer pharmacology at Newcastle University. Ratain says achieving the right dosage requires an understanding of clinical pharmacology and a randomised trial.
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Aqilion and Merck partner to develop TAK1 protein inhibitors
Pharmaceutical Technology
FEBRUARY 16, 2023
Merck will be responsible for leading the preclinical pharmacology and biology trials. It will aim to develop advanced TAK1 therapeutics for various inflammatory and autoimmune diseases, including neurological diseases. Aqilion will handle the design and synthesis of the new small molecule TAK1 inhibitors.
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Abliva’s NV354 receives ODD from US FDA
Pharma Leaders
APRIL 17, 2023
NV354 has indicated to be safe and efficacious in pre-clinical models, with regard to optimal pharmacological properties, including high levels of brain penetration. NV354 complements the lead asset, KL1333, which also has received ODD. This second programme in the Abliva portfolio, NV354 was developed by Abliva scientists.
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Market outlook to 2032: future trends across the seven major markets
European Pharmaceutical Review
JANUARY 18, 2024
GlobalData’s Analyst covering Neurology and Ophthalmology, Thomas Parker, MPharmacol, predicted that Belsomra would lead the market by 2023. billion by 2023, driven by the launch of Merck’s Belsomra and Eisai’s lemborexant (E-2006). million in sales by 2032. percent sales expected in 2032 within the seven major markets.
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How to Become a Pharmaceutical Sales Representative
Pharmaceutical Representative Training
JANUARY 11, 2021
Next, pharma reps need to have a strong foundation in basic science and pharmacology. Pharmacology is the science of medications and the role they play in the body. This is not always the case with other industries where mergers and acquisitions lead to a higher frequency of layoffs. Can you easily connect with others?
FDA suggests ways to curb constraints with rare disease gene therapy trials
Pharmaceutical Technology
FEBRUARY 8, 2023
Blank acknowledged that in many cases, an exclusively paediatric patient population could lead to difficulties with drawing consent for early phase trials. Still, Blank suggested that companies enroll the patient population that is most likely to benefit, because early phase studies contain the most safety risks.
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Cala® Launches The Cala kIQ™ System, Offering Meaningful Tremor Relief for Patients With Essential Tremor and Now Parkinson’s Disease
Legacy MEDSearch
JUNE 15, 2023
The Cala kIQ System with TAPS therapy offers a non-invasive, non-pharmacologic solution with minimal side effects. Founded in 2014, the company is headquartered in the San Francisco Bay Area and backed by leading investors in both healthcare and technology. New therapies are under development in neurology, cardiology, and psychiatry.
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Reaction Biology to acquire Vyant Bio subsidiary’s operations in US
Pharmaceutical Technology
NOVEMBER 4, 2022
Reaction will also obtain lab facilities, equipment, staff, cell lines and expertise in toxicology, pharmacology, pathology and bio analytics from vivoPharm. This will further extend Reaction's industry-leading drug discovery service suite for customers in the biopharmaceutical sector.
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Understanding a rare disease through the lens of real world and prevalence data
Clarivate
FEBRUARY 28, 2023
Degeneration of the retinal ganglion cells causes rapidly progressing vision loss, leading to permanent (non-painful) blindness within a year. Frontiers in Pharmacology; 13:1089033; DOI: 10.3389/fphar.2022.1089033 Learn more about the Clarivate real world data offering here. References [1] Sundaramurthy S et al. ” Cureus; V.12;
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Pharmacodynamics and Pharmacokinetics: The Science Behind Drug Action (Understanding the different characteristics of a drug and how they are important for therapeutic success)
Pharmaceutical Representative Training
JANUARY 30, 2025
Therapeutic drug monitoring is used to obtain peak and trough levels to determine drug serum concentration which tells us if a drug is efficacious or is leading to toxic levels. warfarin) which leads to higher plasma concentrations. Rang & Dale’s Pharmacology. The Pharmacological Basis of Therapeutics.
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Advancing AOCs to transform the delivery of RNA therapeutics
European Pharmaceutical Review
DECEMBER 11, 2023
Known linkers in the RNA field are used to bond together the two pharmacologically active molecular entities and can be applied to multiple oligonucleotide modalities. Research advances are also helping us learn more about how RNA is processed, potentially leading to new strategies to alter dysfunctional RNA. 2019 ;42:385-406.
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14th Annual RNA Therapeutics Conference
pharmaphorum
NOVEMBER 1, 2022
Benefits of attending: Explore how mRNA leads the way in the genetic medicine space as the next generation of novel drug modalities. Director, Clinical Pharmacology. Investigate the latest trends in AI drug discovery as a tool for designing novel RNA based therapeutics. Chief Medical Officers. Chief Technical Officers. Head of Biology.
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Top-10 ways for Pharma to leverage AI according to…AI
Impetus Digital
AUGUST 2, 2024
In turn, this can support decision-making and lead to more efficient inventory management and faster delivery times, enhance supply chain visibility and transparency, and avoid overproduction and waste.
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The Role of Certifications in Advancing Your Career in Medical Sales
Rep-Lite
FEBRUARY 28, 2024
Sales professionals gain a deeper understanding of complex topics like pharmacology, anatomy, physiology, disease pathology, and the latest advancements in medical technology. These certifications delve into specific areas of the healthcare industry, such as pharmaceuticals, medical devices, biotechnology, or healthcare regulations.
Madrigal sees road to approval for NASH drug resmetirom
pharmaphorum
DECEMBER 20, 2022
The condition is largely associated with obesity and an unhealthy diet and lifestyle, and is on the rise in industrialised nations, leading to estimates it could present a market opportunity worth tens of billions of dollars worldwide.
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Uncovering the potential of ADCs to target tumours
European Pharmaceutical Review
JULY 18, 2024
She leads Ipsen’s Early Development Portfolio across the company’s three therapeutic focus areas (Oncology, Rare Disease and Neuroscience). This covers nonclinical drug safety, translational and clinical pharmacology, drug metabolism and pharmacokinetics (DMPK) and pharmacometrics.
Strategies for Streamlining Small Molecule Formulation Development When Bridging from Candidate Selection to First-in-Human Clinical Testing
Pharmaceutical Technology
FEBRUARY 13, 2023
Key considerations in the candidate selection stage The first step in a drug development program is choosing the optimum molecule from a range of potential leads that have been optimized within drug discovery. We start by using in-silico modeling of any pre-existing data associated with the lead compounds.
Biosimilar medicines: the intersection of access, affordability, and innovation
European Pharmaceutical Review
JANUARY 31, 2025
Over 100 biosimilar medicines are approved for nearly 30 reference medicines, testimony to the rigour of the scientific standards leading to the European authorisation process. These reconsiderations lead the way to liberating untapped potential from biological standards of care. She holds a MSc in Pharmacology. References 1.
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The route to enhanced gene therapies
European Pharmaceutical Review
JULY 25, 2024
Roger ‘s work has involved leading the strategy and build of UCB’s global gene therapy research platform and digital transformation in global research. Palframan received his BSc in pharmacology at King’s College London and his PhD in immunology at Imperial College London.
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3D Medical Animation: Transforming Healthcare Communication with Precision and Clarity
Infuse Medical
DECEMBER 17, 2024
We create animations that appeal to the target audience from depicting pharmacological processes of action to elucidating complicated medical gadgets. A trusted partner for major healthcare providers Some of the biggest medical device firms in the business as well as some of the biggest healthcare providers have worked with Infuse Med.
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Miracor Medical Announces FDA IDE Approval For PiCSO® Pivotal Study
Legacy MEDSearch
AUGUST 25, 2022
Early non-randomized European studies have suggested that this leads to reduced incidence of coronary microvascular obstruction (MVO) [3,4] and smaller infarct size, which are both strongly correlated to improvement in heart failure hospitalizations and reduced mortality following primary PCI [5].
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Botanical drugs – what is the best way forward for regulatory and market approval?
European Pharmaceutical Review
JULY 4, 2024
Prior to joining Fieldfisher, Taly spent four years working as in-house counsel for a leading tech company helping launch products across multiple EU markets. She obtained a degree in physics from MIT prior to attending University of Pennsylvania Law School.
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2022 Medical Sales Rep Salary
Map My Customers
MARCH 31, 2022
As a pharmaceutical sales rep, there are appointments and meetings with doctors and professionals that need to stay up to date with the latest pharmacology treatment options for their patients. Pharmaceutical sales representatives will be the face of the company for drug and treatment manufacturers.
The Buyers Guide to Supercharging your Pharma Field Force Sales Performance
Quantified
JUNE 28, 2022
The reality is that leading companies are looking for ways to drive impact that go beyond optimizing reach and frequency. To do this, they will not only need new knowledge but a substantially better ability to engage, connect and influence the HCP, leading to more meaningful interactions and increased conversion.
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Embracing green innovation in life sciences
European Pharmaceutical Review
JANUARY 13, 2025
Research demonstrates that the greenest inhaler is the one that is used and that leads to disease control. If we want to lead the way in green innovation and show that the UK is open for business, we need a broader definition and recognition of innovation. Pulmonary Pharmacology & Therapeutics. 2024; 85: 1-9.
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Considerations for a successful tech transfer of a biologics upstream process
European Pharmaceutical Review
JANUARY 27, 2025
By starting collaborations early, relationships are initiated and involvement in the project happens during inception, leading to ownership and thereby maximising results. She completed post-doctoral training at Johnson & Johnson and the University of California San Diego in pharmacology and bioengineering.
Confo Therapeutics and AbCellera partner on GPCR-targeting antibodies
Pharmaceutical Technology
JUNE 15, 2023
Entering into select, high-value collaborations allows us to efficiently deploy our platform together with leading companies while we continue to build out our own pipeline of innovative and impactful medicines.”
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