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Revolutionising quality control In the backdrop of stringent quality standards and regulatory demands inherent to pharmaceuticalmanufacturing, the addition of AI technologies introduce a paradigm shift. Tuijin Jishu/Journal of Propulsion Technology, 44(3), 1384-1392.
September 2023 saw a wave of new pharmaceuticalmanufacturing facility expansions and launches across Europe. Importantly, each site features advanced technologies to support development and manufacture of these therapeutics. Materials and financing costs are high and squeezing manufacturers and their customers alike.
According to the European Federation of Pharmaceutical Industries and Associations (EFPIA), more than 600 essential medicines are at risk if a proposed restriction on the use of fluorinated substances, per- and polyfluoroalkyl substances (PFAS) across pharmaceuticalmanufacturing in the EEA, is implemented.
To address these issues, companies should adopt more advanced production strategies such as continuous flow chemistry, as they can shorten manufacturing processes, increase productivity and throughput. The result is efficient, cost-effective and high-quality (bio)pharmaceutical production.
The first industrial-scale pharmaceuticalmanufacturing facility for production of lead-212-based radioligand therapies has been inaugurated. This news follows the company beginning construction on a similar facility in France , which is set to produce lead-212 radioligand therapies for the European market.
The Association of the British Pharmaceutical Industry (ABPI) has drawn attention to a new report , which has emphasised the importance of UK advanced manufacturing requiring a long-term strategy to ensure its continued success. Article: Are we globally prepared for the next pandemic?
Drastic steps need to be taken if the UK is to reverse a steep decline in medicines manufacturing in recent years, according to a cross-industry coalition. Since 2010, the UK has fallen from 4th to 98th place in overall trade balance in pharmaceuticals, due to fierce global competition, according to the MMIP. It’s not all bad news.
The pharmaceutical industry is becoming increasingly conscious of emissions and the importance of sustainable manufacturing. Globally, the pharmaceutical sector emitted around 52 megatonnes of CO 2 in 2015, the most recent period for which detailed numbers are available.
A new global Minimized Risk of Antimicrobial Resistance (AMR) certification has been launched to promote and demonstrate responsible antibiotic manufacturing in the global pharmaceutical supply chain. BSI, a UK standards body, developed the new certification to the Antibiotic Manufacturing Standard published in June 2022.
There has been a steady stream of developments in the vaccine manufacturing space throughout 2023. A notable milestone was Moderna’s announcement in April that it had, following finalisation of a ten-year strategic partnership with the UK Government, commenced construction of its mRNA vaccine manufacturing technology centre.
In the interview, conducted at CPHI Barcelona, Krishna Venkatesh, Global Head, Sterile Manufacturing Operations at Dr Reddy’s Laboratories explores industry’s growing focus on achieving end-to-end connectivity, as well as the potential of automation and track and trace solutions. KV : We have seen two specific elements.
He leads the Program on Regulation, Therapeutics, and Law at Brigham and Women’s Hospital in Boston. Meanwhile, the top 25 pharmaceutical companies reported a “healthy average operating margin of 22 percent” at the end of 2017, according to an analysis by GlobalData.
The inventory position of 28 major pharmaceuticalmanufacturers in 2022 has been revealed in an annual report. Yet the balance sheets of the pharmaceuticalmanufacturers included in the report showed limited evidence of this. Inventories grew to a combined total of $150bn in 2022, the analysis showed.
International companies investing in the emerging market of Brazilian pharmaceuticalmanufacturing will see a higher return on investment than from developed market equivalents, if they choose to compete with local manufacturers to supply Brazil’s growing market and the greater South American region.
Importantly, spectroscopy techniques utilising molecular spectroscopy enable manufacturers to gain “real-time input on process parameters, which helps firms improve production processes, enhance productivity, and reduce costs”. This enables pharmaceutical companies to monitor their manufacturing processes at various stages.
Discover the leading patient adherence pharmaceutical companies. Pharmaceutical Technology has listed the top patient adherence pharmaceutical companies based on our intel, insights and decades-long expertise in the sector.
Pharmaceutical wholesalers act as intermediaries between pharmaceuticalmanufacturers and retailers and facilitate the delivery of the right medicines in a timely, efficient, and secure manner. Discover the top pharmaceutical wholesalers.
Now, this service-centred model is delivering advantages in the pharmaceutical industry, with costly manufacturing facilities and processes becoming widely available on an on-demand basis. But with a single dedicated cleanroom environment costing around $2.5 Meeting strict standards. Enter cleanrooms-on-demand…. The future of COD.
However, despite this significant market share, the Japanese market is likely to become a less attractive market for international pharmaceutical companies based on recent findings from the Office of Pharmaceutical Industry Research (OPIR).
UKRI highlighted that overall, these investments will “enhance the UK’s global competitiveness by supporting research and innovation that leads to new and disruptive biomanufacturing processes across the UK.” Curious about sustainability in pharmaceuticalmanufacturing and the supply chain?
AbbVie , an international R&D biopharmaceutical enterprise has celebrated its 20th anniversary by investing in extensive renovations at its manufacturing site in Cork, Ireland. The €60 million expansion will open 70 new jobs in sterile manufacturing, quality control and engineering in 2025. AbbVie announces Michael Severino, M.D.
Although the driving factors of the shortage are complex, the bottom line is that drug manufacturers, particularly those that produce generic drugs, can’t afford to stockpile raw materials and products to prepare for shortages due to financial, storage capability, and product expiry limitations.
The pharmaceutical freeze-drying systems market is expected to be driven by the integration of smarter technologies in lyophilisation methods such as electron microscopy, biochemistry, and advancement in surgeries. The companies offer systems for more dynamic freeze-drying of products with more precision in control.
The pharmaceutical supply chain is a global and complex network that includes a wide range of stakeholders such as pharmaceuticalmanufacturers, wholesale distributors, and pharmacy benefit managers (PBM), to ensure efficient and timely delivery of medications to the patients.
The US Food and Drug Administration (FDA)’s Center for Drug Evaluation and Research (CDER) through the Office of Pharmaceutical Quality in 2021 embarked on an initiative to develop a framework for establishing a pharmaceuticalmanufacturing site quality rating system, the Quality management maturity (QMM) programme.
Pharmaceutical Technology has listed the leading API chemical companies in contract marketing based on its intel, insights, and decades of experience in the sector. The post Leading API chemical companies in contract marketing appeared first on Pharmaceutical Technology.
To appreciate the scope of the challenge facing the pharmaceutical market, as well as patients across the globe, we must understand that there are two distinct threats – ‘counterfeit’ and ‘falsified’ medicines. These may be mislabelled or produced in fake packaging and, most dangerously, there is no regulation around their manufacture.
However, because of manufacturer discounts and rebates, the extent to which increases in wholesale list prices are associated with amounts paid by patients and insurers is poorly characterized. Drug wholesale list prices have doubled in recent years. This is an industry that doesn’t care about what people think of them.
The introduction of rapid microbiological testing methods, such as biofluorescent particle counters for real time detection of microbial contamination, has had an important impact on cell and gene therapy manufacturing. Environmental Monitoring In-Depth Focus 2024 How is eXmoor navigating these advances in the sector? What were the solution?
SMS Pharmaceuticals Ltd- Walk-Ins for Production/ Quality Control/ IT Dept. SMS Pharmaceuticals Ltd is one of the leadingpharmaceuticalmanufacturing companies in India with world -class facilities, with a wide range of process equipment fully compliant with the cGMP and WHO Standards. On 24th Sept’ 2022.
Commercial dose companies form a critical component of the pharmaceuticalmanufacturing industry’s value chain. The dose form manufacturing follows API manufacturing to produce the final dosage form (FDF such as tablets and injectables. Discover the leading commercial dose companies in contract marketing.
For instance, in pharmaceuticalmanufacturing, mistakes in training can lead to contamination or waste, which can cause businesses unnecessary headaches. Lynne Byers, global managing director, Pharmaceuticals and Dietary Supplements Consulting, NSF. Embrace mobile learning.
Breast cancer treatment is an intricate field, with ongoing research and development leading to new and innovative therapies. Lab data, coupled with strategic HCP engagement, plays a crucial role in helping pharmaceuticalmanufacturers navigate this complex landscape.
Contract marketing companies support pharmaceutical companies in creating, improving, and maintaining their brand, as well as reducing risk, and ensuring better product placement in the market. The post Leading commercial dose (non-sterile) companies in contract marketing appeared first on Pharmaceutical Technology.
Enhancing Development and Manufacturing Operations through Environmentally Sustainable Means The pharmaceutical industry’s evolving nature impacts patient care due to ongoing drug shortages from weakened operations. This not only boosts sustainability but also enhances process efficiency, leading to lower manufacturing costs and risks.
However, despite this significant market share, the Japanese market is likely to become a less attractive market for international pharmaceutical companies based on recent findings from the Office of Pharmaceutical Industry Research (OPIR).
From the manufacturer perspective, payer policies and legislation on combination therapy pricing are impacting global development, pricing, access, and commercialization strategies. When 1+1 ≠ 2 In theory, combining two or more branded agents can lead to a price that exceeds SoC monotherapy. Certain markets (e.g.,
Andreas Häner (AH): Roche, along with other pharmaceutical companies, acknowledges concerns about pharmaceuticals in the environment (PiE). Wastewater samples taken at or close to the point of generation in manufacturing typically have a much higher API concentration, thus require less analytical sensitivity.
The pharmaceutical industry requires specialised and cost-effective commercial packaging solutions to improve efficiency and preserve the integrity of products through the entire supply chain, from primary packaging and labelling to shipping, delivery, storage and distribution to end users.
The pandemic effectively shut down supply chain paths overnight, and as a result, pharmaceuticalmanufacturers have faced delays and bottlenecks, which have caused drug shortages in healthcare systems. Above all else, manufacturers need to get their houses in order. It can be done, of course, but it is costly.
Despite this toll, AMR has often been called the ‘silent pandemic’: 4 “AMR is sadly silent because it has not been discussed like other pandemics – and of course has been in the shadow of the COVID-19 pandemic in recent years,” commented Melissa Gong Mitchell, Secretariat Lead of the AMR Industry Alliance.
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