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Strategies for Streamlining Small Molecule Formulation Development When Bridging from Candidate Selection to First-in-Human Clinical Testing

Pharmaceutical Technology

However, there is a high level of attrition during the pharmaceutical research and development process, which is an indicator of the vast number of potential drug substances considered for progression. Therefore, it is vital to choose molecules for pharmaceutical development very carefully.

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Innovations & Challenges in Brain Health

PM360

They are difficult to diagnose early in a disease, the regulatory endpoints are often unprecedented and challenging, and many drugs struggle to get into the brain. The downside is that it also keeps most potential drug treatments from reaching the brain. Greene was the general manager of Oncology at Millennium Pharmaceuticals, Inc.,

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Paving the way for anti-Abeta active immunotherapy

European Pharmaceutical Review

Targeting toxic species of Abeta, such as multimers (with aducanumab and lecanemab) or pyroglutamate Abeta3-42 (with donanemab), induced significant removal of Abeta plaque load in the brains of Alzheimer’s patients, leading to the delay in cognitive decline.

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The Future for Biotesting

Pharmaceutical Technology

Now the company is a GLP-certified contract research organisation that focuses on three main domains. Firstly, there is a comprehensive toxicological service for human and veterinary pharmaceuticals and biopharmaceuticals, food additives, chemicals and agrochemicals. It will most probably lead to a new anti-flu vaccine.