Fierce Pharma

JUNE 13, 2023

By: William Blake, Chief Technology Officer, Human-Based R&D | Danaher Life Sciences companies are ushering in a new era of engineering biology, partnering with biopharma leaders to deploy automation, AI and other engineering practices from early research through manufacturing.

Engineering 258

Engineering Biopharma Manufacturing 258

European Pharmaceutical Review

JULY 13, 2023

By re-engineering existing approaches that have already shown clinical promise, there is potential to bring further benefit to the patient community in its fight against cancer. Since then, several next-generation antibodies have been engineered with modifications that enable them to better engage with immune cells.

Engineering 98

Engineering Food and Drug Administration Patients Safety 98

pharmaphorum

NOVEMBER 29, 2023

Startup Cradle tucks in $24m for protein engineering AI Phil.Taylor Wed, 29/11/2023 - 11:48 Bookmark this

Engineering 105

Engineering 105

European Pharmaceutical Review

OCTOBER 28, 2022

As the first-ever Omega Epigenomic Controller (OEC) to be dosed in a patient, this milestone represents a significant step forward…to bringing engineered, programmable mRNA therapeutics to patients,” explained Mahesh Karande, President and Chief Executive Officer of Omega Therapeutics.

Engineering 111

Engineering Patients Medicine Medical 111

MedCity News

SEPTEMBER 6, 2023

In a day of vast innovation, expansion, and acquisitions, an engineering mindset can bring a unique and effective approach to thinking across the system, evaluating the current and future state, standardizing on best practices, and considering upstream and downstream workflows.

Engineering 111

Engineering Patients 111

European Pharmaceutical Review

AUGUST 2, 2024

The post FDA approves innovative engineered cell therapy appeared first on European Pharmaceutical Review. With US approval TECELRA, “there is a renewed sense of hope for this patient community.”

Engineering 98

Engineering FDA Food and Drug Administration Food 98

Fierce Pharma

APRIL 18, 2023

J&J's unstoppable profit engine sputters after $6.9B talc litigation charge fkansteiner Tue, 04/18/2023 - 10:47

Engineering 100

Engineering 100

MedCity News

AUGUST 15, 2023

Generative AI further enhances the value of prompt engineering by synthesizing important insights from various interactions, including text, images, compliant transcripts, and call notes. By automating this process, generative AI quickly transforms on-the-ground insights into robust analytics.

Engineering 98

Engineering Pharma Manufacturing Biopharma 98

Pharmaceutical Technology

APRIL 30, 2024

Discover how this mitochondria-targeting engineered meganuclease is revolutionizing genetic research. Unlock the potential of genetic modification with Precision Biosciences Inc's patented MTEM technology for precise editing of eukaryotic cells.

Engineering 78

Engineering 78

pharmaphorum

NOVEMBER 26, 2024

ZENITH trial of MSD's Winrevair in PAH could add further momentum to an already impressive launch.

Engineering 97

Engineering 97

PharmaVoice

NOVEMBER 2, 2023

From Merck and J&J to AbbVie and Eisai, the oncology field has stayed consistently devoted to churning out important therapies.

Engineering 105

Engineering Pharma 105

MedCity News

JANUARY 25, 2024

The clinical program spans tests of the engineered virus as a monotherapy and as part of combination treatments. CG Oncology’s upsized IPO will support pivotal testing of cretostimogene, an oncolytic virus for non-muscle invasive bladder cancer.

Engineering 129

Engineering Biopharma Pharma 129

MedCity News

NOVEMBER 10, 2024

While it goes after the same target as Gilead Sciences’ Tecartus, Autolus engineered its CAR T-therapy with properties that could improve safety, efficacy, and durability. Autolus Therapeutics’ Aucatzyl is now FDA approved for treating advanced cases of B-cell precursor acute lymphoblastic leukemia.

FDA 126

FDA Engineering Safety Biopharma 126

MedCity News

SEPTEMBER 12, 2023

After Babylon collapsed, a former employee also publicly declared that the AI engine was faulty. doctor David Watkins has been a public critic of Babylon Health for years, during which has received anonymous emails from Babylon employees saying that the company’s AI is a sham.

Engineering 143

Engineering Doctors Healthcare Healthcare 143

MedCity News

MAY 28, 2024

Johnson & Johnson is acquiring a bispecific antibody that Numab Therapeutics engineered to address two pathways associated with the inflammation and itching of atopic dermatitis. It’s J&J’s second immunology acquisition this month.

Engineering 121

Engineering Biopharma Pharma 121

Healthcare Success

MAY 9, 2023

A strong healthcare SEO strategy requires time, money, or both, to get your website found on the first page of search engine results. Black hat SEO techniques involve tricking users and search engines to get pages to the top of Google and other major search engines. This creates silos (e.g.,

Healthcare 98

Healthcare Healthcare Engineering Marketing 98

MedCity News

MARCH 18, 2024

Contineum Therapeutics, which emerged from a Verant Ventures startup creation engine, has filed paperwork for an IPO. The biotech’s clinical-stage pipeline spans multiple sclerosis, idiopathic pulmonary fibrosis, and depression.

Engineering 110

Engineering Biopharma Pharma 110

MedCity News

NOVEMBER 10, 2023

Cargo Therapeutics will use most of the IPO proceeds for clinical testing of a cell therapy engineered to overcome a common way cancers develop resistance. This program is based on research from the National Cancer Institute.

Engineering 122

Engineering Biopharma Pharma 122

MedCity News

MAY 10, 2024

By doing this, CybergenX is seeking to accelerate the potential of engineering biology in drug manufacturing. The company, called CybergenX, is seeking to integrate AI-powered cybergenetic technology into the synthetic biology field.

Manufacturing 118

Manufacturing Engineering Biopharma 118

pharmaphorum

AUGUST 2, 2024

FDA has approved Adaptimmune's Tecelra for synovial sarcoma, the first engineered T-cell therapy for solid tumours

FDA 105

FDA Engineering 105

MedCity News

JULY 19, 2024

Harvard spinout GRO Biosciences has a platform technology for engineering therapeutic proteins that won’t prompt an immune response against them. The startup’s lead program is a potential competitor to an Amgen gout drug acquired in a multi-billion dollar deal.

Engineering 118

Engineering Leads Biopharma 118

PharmExec

JULY 7, 2023

Through the power of large language models and generative AI, pharma and biotech companies are transforming medical information delivery by offering direct, trustworthy, and accurate answers to patients and healthcare providers, significantly reducing time and frustration.

Engineering 98

Engineering Healthcare Provider Patients Pharma 98

MedCity News

OCTOBER 25, 2023

HealthBook+ provides a way for individuals to aggregate and use their personal health information safely and securely to power AI engines that direct people to their next best health action. Importantly, it also gives employers predictive insights to help them provide the most relevant benefits for their employees.

Engineering 124

Engineering 124

MedCity News

OCTOBER 24, 2024

Radiant Biotherapeutics’ Multabodies are antibodies engineered to offer better binding strength to their targets. The preclinical startup’s lead program goes after a cancer immunotherapy target being pursued by several biotech companies already in early clinical development.

Engineering 115

Engineering Leads Biopharma Pharma 115

MedCity News

FEBRUARY 17, 2023

Chiesi drug Lamzede is an engineered version of an enzyme that’s lacking in patients with the rare disease alpha-mannosidosis. FDA approval of the Chiesi drug comes about five years after European regulators authorized the product.

FDA 119

FDA Engineering Patients Biopharma 119

Authentic Influence Group

SEPTEMBER 24, 2021

The conversation evolves to cover body language, social engineering, authentic communication, persuasion vs influence vs manipulation. Here's a quick recap: We discuss why clear communication, that is easily digestible by your audience is essential if you're to have the impact you want in influencing people.

Engineering 130

Engineering 130

MedCity News

MARCH 3, 2023

True to its name, the startup’s approach involves putting more cargo and more complex cargo onto engineered T cells. Cargo Therapeutics is developing CAR T-cell therapies that overcome ways cancers evade currently available treatments.

Engineering 116

Engineering Biopharma Pharma 116

MedCity News

OCTOBER 21, 2022

Surge Therapeutics’ hydrogel is engineered to deliver a cancer immunotherapy. Rather than replace surgery, CEO Michael Goldberg says the hydrogel could supplement this standard of care for solid tumors. The startup’s Series A financing will support the technology’s first test in humans.

Engineering 119

Engineering Biopharma Pharma 119

World of DTC Marketing

JANUARY 4, 2021

6ix : Don’t measure each channel; measure all of your DTC as one integrated engine designed to help people chose your product. Enough is enough; please develop a relevant content strategy to help people navigate false and misleading health information. 7even : Every brand team should have an integrated digital marketing person.

Marketing 271

Marketing Media Medical Prescription 271

European Pharmaceutical Review

OCTOBER 20, 2022

In this article, Sangamo Therapeutics’ Chief Scientific Officer, Jason Fortenot, explains why CAR Tregs may become transformational therapeutics for immune-mediated diseases, highlighting the challenges his company has overcome to get the first ever engineered Treg therapy into clinical trials. How do CAR Tregs differ from T cells?

Engineering 140

Engineering Side effects Manufacturing Patients 140

MedCity News

JUNE 22, 2023

Elevidys is an engineered version of a gene intended to restore function lost to the mutation at the root of the inherited muscle disease. Sarepta Therapeutics’ Elevidys is now the first FDA-approved gene therapy for Duchenne muscular dystrophy.

FDA 111

FDA Engineering Biopharma Pharma 111

European Pharmaceutical Review

MARCH 8, 2023

Adrian Rawcliffe, Adaptimmune’s Chief Executive Officer asserted that the combined companies will work to gain “approval for the first engineered T-cell receptor (TCR) T-cell therapy for a solid tumour – afami-cel for the treatment of synovial sarcoma.”

Engineering 119

Engineering Pharmaceutical Patients 119

PharmaTech

APRIL 19, 2024

Jay Rajagopalan, senior director—Engineering & Product Management for Malema at PSG Biotech, shared insights at on how current industry trends are shaping the development and advancement of sensor technologies.

Engineering 96

Engineering Management 96

MedCity News

OCTOBER 4, 2023

Iambic Therapeutics brings together software engineers and drug-hunting scientists, all sharing the goal of using artificial intelligence to optimize properties of small molecule drugs. The startup will apply its Series B financing to a cancer drug pipeline that includes two candidates on track for the clinic in 2024.

Engineering 111

Engineering Biopharma 111

European Pharmaceutical Review

JUNE 13, 2024

Some of these improvements include: Advanced cell line engineering techniques : this includes CRISPR/Cas9-mediated genome editing, enabling the development of stable cell lines optimised for AAV production.

Manufacturing 145

Manufacturing Food and Drug Administration Engineering Safety 145

Medgadget

OCTOBER 31, 2023

A team at Columbia University School of Engineering and Applied Science has developed a technique to enhance chimeric antigen receptor (CAR) T cell therapy in solid tumors. The technique involves engineering E. coli bacteria, that naturally tend to accumulate in the immune privileged core of solid tumors.

Engineering 96

Engineering Patients 96

World of DTC Marketing

SEPTEMBER 18, 2020

Most often, patients relied on the internet (specifically multiple myeloma websites [94%] and general search engines [92%] to find information about multiple myeloma). However, about half of patients (51%) surveyed reported challenges in identifying which information sources are trustworthy.

Physicians 259

Physicians Patients Engineering Doctors 259