Sat.Oct 29, 2022 - Fri.Nov 04, 2022

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Why are Healthcare Costs So High? Blame the Middlemen

MedCity News

Large employers, particularly self-insured companies, can demand a better and fairer system. They can use their contracting power to insist that their plans cover all FDA approved drugs.

Insurance 143
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GSK speeds up the race to bring first RSV vaccine for older adults to market

Pharmaceutical Technology

After decades of setbacks, the respiratory syncytial virus (RSV) vaccine field has bounced back with positive Phase III trial results in older adults. There are currently five players in the race, with vaccines in Phase III of development from GlaxoSmithKline (GSK) , Pfizer , Johnson & Johnson , Moderna and Bavarian Nordic. However, recent data from GSK’s sub-unit vaccine, GSK-3844766A, have pushed the candidate to the top, with the highest efficacy demonstrated in a pivotal trial to date.

Marketing 135
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“Universal” CRISPR-edited T cells improve resistant leukaemia

European Pharmaceutical Review

Researchers at Great Ormond Street Hospital for Children (GOSH) and University College London (UCL) Great Ormond Street Institute of Child Health (UCL GOS ICH) have used “universal” CRISPR-edited cells in humans for the first time to treat B-cell acute lymphoblastic leukaemia (B-ALL) child patients with engineered donor T cells. The treatment did not require matching donor cells, a major step in developing gene-edited cells for cancer treatment.

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Could digital therapeutics provide a solution against opioid abuse?

pharmaphorum

Digital therapeutics are rapidly coming into the foreground to treat a variety of conditions. Ben Hargreaves discovers how chronic pain could be a key area for digital therapeutics, as they offer non-addictive and effective relief from the condition. The struggle to manage pain for individuals has been one that goes back a long way in history, with one of the earliest recorded medical prescriptions being for opium.

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AI Strategies for Sales Managers: How to Cut Down on Tedious Admin Work

What if you could help your sellers stop wasting 72% of their day on non-selling activities and focus on bringing in revenue? Incorporating AI in your enablement workflows can help you cut down on busy work, get projects done faster, and let your team (and you!) focus on making a bigger impact. We put together this guide to show you how to use AI to cut time and costs for projects, including collateral creation, development of training videos, and automating tedious processes.

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From transactions to transformation: How to deliver on the patient-centric promise

MedCity News

We’ve been talking about improving patient satisfaction and creating a more patient-centric care experience for years. But we’ll never get there if we continue to be focused on transactional healthcare, which is where our efforts toward interoperability have traditionally been drawn.

Patients 143
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Pfizer records 6% decline in revenue in Q3 2022

Pharmaceutical Technology

Pfizer has reported a 6% decline in revenue to $22.6bn in the third quarter (Q3) of 2022 as against $24bn in the same quarter last year. In the quarter, revenues rose 2% operationally on omitting contributions from Covid-19 therapies, Paxlovid and Comirnaty. Reduction in revenues from Comirnaty outside the US and reduced revenues for some Comirnaty-linked manufacturing works carried out on behalf of BioNTech, Xeljanz and Sutent worldwide were the key drivers that contributed to the revenue dec

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Verge Genomics takes AI-sourced drug for ALS into clinic

pharmaphorum

Verge Genomics has joined a select group of biotechs who have taken a drug discovered and developed using artificial intelligence into human testing. The small-molecule PIKfyve inhibitor – called VRG50635 – has been administered to the first subject in the phase 1 trial involving healthy volunteers, according to the San Francisco-based biotech, which was founded in 2015 by Alice Zhang and Jason Chen.

Pharma 131
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What will the next generation of medical coding look like? [Sponsored]

MedCity News

A transformation is underway in medical coding as automation permeates revenue cycle management, raising questions such as: How will automation affect how medical coders work? How advanced is coding automation currently? What kind of skill sets will be needed for these new types of coding?

Medical 140
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Inside the European mass shift to data-driven health solutions

Pharmaceutical Technology

In a few weeks, the EU-funded research project Darwin EU will announce its first batch of data partners for the ambitious real-world data -driven Horizon 2020 project. This project centres around the use of electronic health records (EHRs) from different European countries to drive research and improve responses to expected and unexpected crises. A major objective of this project hinges on exploiting national EHR data to complete observational studies quicker than industry standards.

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Symani Microsurgical Robotic System: Interview with Mark Toland, CEO of Medical Microinstruments

Medgadget

Medical Microinstruments , a medtech company with offices in Pisa, Italy and Delaware, USA, has developed the Symani Microsurgical Robot. The robotic system is designed to assist with microsurgical procedures, and it boasts a variety of advanced features to achieve this goal. These include a suite of the world’s smallest wristed surgical instruments, tremor reducing technology, and motion scaling (7-20X), to allow surgeons to perform very small and precise movements.

Medical 109
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Actinium eyes filing as conditioning drug for AML aces trial

pharmaphorum

Actinium Pharma is on course to submit its targeted radiotherapy for acute myeloid leukaemia (AML) patients needing a bone marrow transplant in the US, buoyed by top-line data from a pivotal trial. The New York biotech said today that the SIERRA trial of Iomab-B – an antibody armed with a radioisotope designed to deliver targeted treatment to tumours and spare healthy tissues – met its primary objective.

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Guaranteed’s Funding Nears $10M on Journey to Improve End-of-Life Care

MedCity News

Tech-enabled hospice provider Guaranteed recently closed a $6.5 million seed round, bringing its total funding to $9.25 million. Jessica McGlory founded the startup a year ago so that patients and their families can have more dignified and holistic end-of-life care experiences than what she and her father went through.

Patients 131
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Recurrent drug shortages signal onerous outlook for cardiovascular care

Pharmaceutical Technology

Drug shortages continue affecting cardiovascular clinical practice across the world, reflecting rising demand and cost-effective manufacturing challenges. While the stock of currently affected drugs is expected to improve as production is increased in the near future, experts say it is likely that the cardiovascular sector will be particularly affected by such shortages in the long run as demand continues to grow from an aging population.

Medicine 111
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Uncover Hidden Consumer Insights & SEO Opportunities with Google Trends

Healthcare Success

Google Trends is a powerful but underutilized tool that helps healthcare marketers. Conduct search engine optimization (SEO) research, Identify current trends, Find out what people are interested in, And build better, more relevant campaigns. It also allows marketers to analyze search term popularity over time, explore related keywords, and compare how search terms vary across different geographical areas.

Marketing 109
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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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First virtual clinical trial examines two promising Alzheimer’s drugs

European Pharmaceutical Review

A new computer model has successfully simulated a clinical trial evaluating the efficacy of aducanumab and donanemab for Alzheimer’s disease (AD), establishing a gradual increase in dosage up to the maximum dose helps to minimise cognitive decline and limit side effects. . The US-based researchers modelled personalised treatments for each virtual patient, assessing US Food and Drug Administration-approved aducanumab and donanemab, a therapy currently being evaluated and other potential AD

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Gynecological Health Startup Eyes US Launch with $11.5M in Series A Funding

MedCity News

With the money, Daye is looking to reach more people with its products and services, whether that’s in the U.S., U.K. or Europe, Milanova said. The company will also expand research in gynecological health, focusing on conditions like endometriosis, PCOS and menopause. .

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Roche’s Actemra gets Health Canada approval for Covid-19 treatment

Pharmaceutical Technology

Hoffmann-La Roche (Roche Canada) has received approval from Health Canada for Actemra IV (tocilizumab for injection) vials to treat Covid-19 patients. The treatment is indicated for adult Covid-19 patients who are on systemic corticosteroids and need additional oxygen, non-invasive or invasive mechanical ventilation, or extracorporeal membrane oxygenation.

Patients 105
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Why blockchain is big pharma’s big focus

pharmaphorum

To address the supply chain vulnerabilities of the pharma industry, an innovative, collaborative blockchain-based system could help to keep track of drugs in transit and ensure they are stored in the correct conditions. The pace of technological advancement and focus in this area suggests that such a solution could be coming soon. While most supply chains were impacted by the Covid-19 pandemic, the demands it placed on pharmaceutical and medical supply chains were immense and underlined the impo

Pharma 109
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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New therapy for anaemic myelodysplastic cancer patients

European Pharmaceutical Review

Bristol Myers Squibb (BMS) has announced Reblozyl ® (luspatercept-aamt), the first erythroid maturation agent, showed improvement in red blood cell transfusion independence (RBC-TI) and haemoglobin (Hb) increase in severely anaemic adults with very low, low or intermediate-risk myelodysplastic syndromes (MDS). Reblozyl is a first-line therapy that promotes late-stage red blood cell maturation in animal models.

Patients 105
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AHA: 78% of Hospitals Say Experience With Commercial Insurers Is Worsening

MedCity News

Less than 1% of hospitals and health systems said their relationship is improving and the rest said it has stayed the same. The American Hospital Association specifically called out commercial insurers for their practices on prior authorization and claims denials and delays.

Insurance 121
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While DCTs get all the hype, some industry insiders say the future is a digital hybrid

PharmaVoice

Leaders at Veeva believe the wording around decentralized trials has been exaggerated, and that a bigger-picture outlook is important as the pandemic winds down.

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Lilly says Mounjaro launch is “viral in nature”

pharmaphorum

One of the highlights of Eli Lilly’s third-quarter results was the rapid uptake of new type 2 diabetes therapy Mounjaro, which added more than $97 million in US sales alone in what has been described as “viral” take-up by the drugmaker. Lilly’s head of diabetes, Mike Mason, said on the company’s results call that the rollout of Mounjaro (tirzepatide) was “really unprecedented” for a new diabetes therapy in the US, and had been driven by “tremendous

Sales 105
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How to Prove Marketing Value: Demonstrate Content ROI and Contribution to Sales

Every marketer knows how important it is to prove their efforts drive sales opportunities, but that’s easier said than done. When problems like sales and marketing misalignment, lack of data, and wasted efforts persist, marketers can’t measure, prove, or increase their impact on revenue at a time when demonstrating marketing value is critical. Using analyst and expert data, this guide to marketing impact and content attribution explains: How B2B buyers use content The most common types of conten

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Could GSK offer the first RSV older adult vaccine?

European Pharmaceutical Review

GSK has announced the European Medicines Agency (EMA) has validated a marketing authorisation application (MAA) under accelerated assessment for its respiratory syncytial virus (RSV) vaccine for adults above 60. If approved, the vaccine could be the first vaccine to prevent RSV lower respiratory tract disease (LRTD) in older adults. Accelerated assessment?

Medicine 105
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3 Lessons From Israel’s World-leading Clinical Data-sharing System

MedCity News

Israel has a powerful tech ecosystem combined with practical government support. The nation’s leaders don’t tell entrepreneurs what to do — but they do provide clarity around the challenges that the healthcare sector is facing, and help gently steer innovation in the right direction.

Leads 121
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Furry Soft Robot Helps Patients During Unpleasant Medical Procedures

Medgadget

A team of researchers at the University of Tsukuba in Japan has developed a fluffy soft robot that patients can interact with to reduce their stress and fear when undergoing painful or uncomfortable medical procedures. For some patients, particularly children, a fear of needles or uncomfortable and painful procedures can make such experiences especially challenging, and may mean that they attempt to avoid treatment altogether.

Medical 98
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Johnson & Johnson to Acquire Heart Pump Maker Abiomed

Legacy MEDSearch

Johnson & Johnson, the world’s largest, most diversified healthcare products company, and Abiomed, a world leader in breakthrough heart, lung and kidney support technologies, announced that they have entered into a definitive agreement under which Johnson & Johnson will acquire through a tender offer all outstanding shares of Abiomed, for an upfront payment of $380.00 per share in cash, corresponding to an enterprise value of approximately $16.6 billion which includes cash acquired.

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How to Stay Competitive in the Evolving State of Martech

Marketing technology is essential for B2B marketers to stay competitive in a rapidly changing digital landscape — and with 53% of marketers experiencing legacy technology issues and limitations, they’re researching innovations to expand and refine their technology stacks. To help practitioners keep up with the rapidly evolving martech landscape, this special report will discuss: How practitioners are integrating technologies and systems to encourage information-sharing between departments and pr

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Global pharma confidence highest on record, shows CPhI Pharma Index

European Pharmaceutical Review

Results from CPhI’s 2022 Pharma Index survey , announced at this year’s CPhI Frankfurt, showed pharma confidence in growth , innovation and manufacturing quality has reached record highs, promising positive prospects for the industry in 2023 and beyond. The survey, which offers a collateralised metric of all major categories, acquired data from 400 global pharma companies.

Pharma 103
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Memora Health, Mayo Clinic pilot digital program to improve postpartum care

MedCity News

Mayo Clinic teamed up with digital health platform Memora Health to pilot a new initiative for postpartum patients. They are launching a texting-based program to better engage postpartum patients and have entered a research collaboration to measure the model’s efficacy.

Patients 120
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Woman of the Week: City of Hope’s Gulden Mesara

PharmaVoice

Charged with bridging the 100-year-old research center to its future mission of holistic patient cancer care, Mesara is bringing decades of experience in communications and culture creation.

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MIT and Toyota Improve Robotic Grasping Techniques

Pharmaceutical Technology

Concept: Massachusetts Institute of Technology (MIT)’s Computer Science and Artificial Intelligence Laboratory (CSAIL) researchers have developed a system called ‘series elastic end effectors’ (SEED) that enable robots to use grabbed tools correctly and successfully. It was developed in partnership with the American Toyota Research Institute (a technology research unit of Toyota).

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time