Sat.Oct 29, 2022 - Fri.Nov 04, 2022

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From transactions to transformation: How to deliver on the patient-centric promise

MedCity News

We’ve been talking about improving patient satisfaction and creating a more patient-centric care experience for years. But we’ll never get there if we continue to be focused on transactional healthcare, which is where our efforts toward interoperability have traditionally been drawn.

Patients 144
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Verge Genomics takes AI-sourced drug for ALS into clinic

pharmaphorum

Verge Genomics has joined a select group of biotechs who have taken a drug discovered and developed using artificial intelligence into human testing. The small-molecule PIKfyve inhibitor – called VRG50635 – has been administered to the first subject in the phase 1 trial involving healthy volunteers, according to the San Francisco-based biotech, which was founded in 2015 by Alice Zhang and Jason Chen.

Pharma 136
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Trending Sources

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GSK speeds up the race to bring first RSV vaccine for older adults to market

Pharmaceutical Technology

After decades of setbacks, the respiratory syncytial virus (RSV) vaccine field has bounced back with positive Phase III trial results in older adults. There are currently five players in the race, with vaccines in Phase III of development from GlaxoSmithKline (GSK) , Pfizer , Johnson & Johnson , Moderna and Bavarian Nordic. However, recent data from GSK’s sub-unit vaccine, GSK-3844766A, have pushed the candidate to the top, with the highest efficacy demonstrated in a pivotal trial to date.

Marketing 135
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“Universal” CRISPR-edited T cells improve resistant leukaemia

European Pharmaceutical Review

Researchers at Great Ormond Street Hospital for Children (GOSH) and University College London (UCL) Great Ormond Street Institute of Child Health (UCL GOS ICH) have used “universal” CRISPR-edited cells in humans for the first time to treat B-cell acute lymphoblastic leukaemia (B-ALL) child patients with engineered donor T cells. The treatment did not require matching donor cells, a major step in developing gene-edited cells for cancer treatment.

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AI Strategies for Sales Managers: How to Cut Down on Tedious Admin Work

What if you could help your sellers stop wasting 72% of their day on non-selling activities and focus on bringing in revenue? Incorporating AI in your enablement workflows can help you cut down on busy work, get projects done faster, and let your team (and you!) focus on making a bigger impact. We put together this guide to show you how to use AI to cut time and costs for projects, including collateral creation, development of training videos, and automating tedious processes.

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Why are Healthcare Costs So High? Blame the Middlemen

MedCity News

Large employers, particularly self-insured companies, can demand a better and fairer system. They can use their contracting power to insist that their plans cover all FDA approved drugs.

Insurance 143
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Could digital therapeutics provide a solution against opioid abuse?

pharmaphorum

Digital therapeutics are rapidly coming into the foreground to treat a variety of conditions. Ben Hargreaves discovers how chronic pain could be a key area for digital therapeutics, as they offer non-addictive and effective relief from the condition. The struggle to manage pain for individuals has been one that goes back a long way in history, with one of the earliest recorded medical prescriptions being for opium.

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Clinical success begins early for small molecule drugs

European Pharmaceutical Review

The race to the first-in-human (FIH) milestone is underscored by the rise in expedited programmes such as Fast Track designation, Accelerated Approval, Priority Review designation and Breakthrough Therapy designation. 1 Within these programmes, the ability to identify and solve challenges in the early stages with agility and flexibility is critical to successful early clinical trials that will help advance drugs from late stage through product launch.

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What will the next generation of medical coding look like? [Sponsored]

MedCity News

A transformation is underway in medical coding as automation permeates revenue cycle management, raising questions such as: How will automation affect how medical coders work? How advanced is coding automation currently? What kind of skill sets will be needed for these new types of coding?

Medical 142
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Actinium eyes filing as conditioning drug for AML aces trial

pharmaphorum

Actinium Pharma is on course to submit its targeted radiotherapy for acute myeloid leukaemia (AML) patients needing a bone marrow transplant in the US, buoyed by top-line data from a pivotal trial. The New York biotech said today that the SIERRA trial of Iomab-B – an antibody armed with a radioisotope designed to deliver targeted treatment to tumours and spare healthy tissues – met its primary objective.

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Digital cognitive behaviour therapies recommended by NICE across the NHS

PharmaTimes

Treatment will assist young people and children with symptoms of mild-to-moderate anxiety

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Tips for tackling trial recruitment and retention woes in oncology

PharmaVoice

How new tools are helping companies find and keep cancer patients in clinical studies.

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Guaranteed’s Funding Nears $10M on Journey to Improve End-of-Life Care

MedCity News

Tech-enabled hospice provider Guaranteed recently closed a $6.5 million seed round, bringing its total funding to $9.25 million. Jessica McGlory founded the startup a year ago so that patients and their families can have more dignified and holistic end-of-life care experiences than what she and her father went through.

Patients 134
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Why blockchain is big pharma’s big focus

pharmaphorum

To address the supply chain vulnerabilities of the pharma industry, an innovative, collaborative blockchain-based system could help to keep track of drugs in transit and ensure they are stored in the correct conditions. The pace of technological advancement and focus in this area suggests that such a solution could be coming soon. While most supply chains were impacted by the Covid-19 pandemic, the demands it placed on pharmaceutical and medical supply chains were immense and underlined the impo

Pharma 123
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New device launched for diagnosing prostate cancer

PharmaTimes

CamPROBE may save vital time and money while reducing the risk of infection

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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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Inside the European mass shift to data-driven health solutions

Pharmaceutical Technology

In a few weeks, the EU-funded research project Darwin EU will announce its first batch of data partners for the ambitious real-world data -driven Horizon 2020 project. This project centres around the use of electronic health records (EHRs) from different European countries to drive research and improve responses to expected and unexpected crises. A major objective of this project hinges on exploiting national EHR data to complete observational studies quicker than industry standards.

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Patient Files Class-action Suit Against Advocate Aurora Health Following Data Breach

MedCity News

A patient affected by a data breach at Advocate Aurora Health has sued the healthcare […].

Patients 134
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Symani Microsurgical Robotic System: Interview with Mark Toland, CEO of Medical Microinstruments

Medgadget

Medical Microinstruments , a medtech company with offices in Pisa, Italy and Delaware, USA, has developed the Symani Microsurgical Robot. The robotic system is designed to assist with microsurgical procedures, and it boasts a variety of advanced features to achieve this goal. These include a suite of the world’s smallest wristed surgical instruments, tremor reducing technology, and motion scaling (7-20X), to allow surgeons to perform very small and precise movements.

Medical 109
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Uncover Hidden Consumer Insights & SEO Opportunities with Google Trends

Healthcare Success

Google Trends is a powerful but underutilized tool that helps healthcare marketers. Conduct search engine optimization (SEO) research, Identify current trends, Find out what people are interested in, And build better, more relevant campaigns. It also allows marketers to analyze search term popularity over time, explore related keywords, and compare how search terms vary across different geographical areas.

Marketing 109
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Recurrent drug shortages signal onerous outlook for cardiovascular care

Pharmaceutical Technology

Drug shortages continue affecting cardiovascular clinical practice across the world, reflecting rising demand and cost-effective manufacturing challenges. While the stock of currently affected drugs is expected to improve as production is increased in the near future, experts say it is likely that the cardiovascular sector will be particularly affected by such shortages in the long run as demand continues to grow from an aging population.

Medicine 111
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Gynecological Health Startup Eyes US Launch with $11.5M in Series A Funding

MedCity News

With the money, Daye is looking to reach more people with its products and services, whether that’s in the U.S., U.K. or Europe, Milanova said. The company will also expand research in gynecological health, focusing on conditions like endometriosis, PCOS and menopause. .

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Aelix and Gilead announce results of HIV infection candidate

PharmaTimes

The study evaluated the safety, efficacy and immunogenicity of AELIX’s HIV vaccine

Safety 108
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Lilly says Mounjaro launch is “viral in nature”

pharmaphorum

One of the highlights of Eli Lilly’s third-quarter results was the rapid uptake of new type 2 diabetes therapy Mounjaro, which added more than $97 million in US sales alone in what has been described as “viral” take-up by the drugmaker. Lilly’s head of diabetes, Mike Mason, said on the company’s results call that the rollout of Mounjaro (tirzepatide) was “really unprecedented” for a new diabetes therapy in the US, and had been driven by “tremendous

Sales 105
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How to Prove Marketing Value: Demonstrate Content ROI and Contribution to Sales

Every marketer knows how important it is to prove their efforts drive sales opportunities, but that’s easier said than done. When problems like sales and marketing misalignment, lack of data, and wasted efforts persist, marketers can’t measure, prove, or increase their impact on revenue at a time when demonstrating marketing value is critical. Using analyst and expert data, this guide to marketing impact and content attribution explains: How B2B buyers use content The most common types of conten

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First virtual clinical trial examines two promising Alzheimer’s drugs

European Pharmaceutical Review

A new computer model has successfully simulated a clinical trial evaluating the efficacy of aducanumab and donanemab for Alzheimer’s disease (AD), establishing a gradual increase in dosage up to the maximum dose helps to minimise cognitive decline and limit side effects. . The US-based researchers modelled personalised treatments for each virtual patient, assessing US Food and Drug Administration-approved aducanumab and donanemab, a therapy currently being evaluated and other potential AD

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AstraZeneca & Sanofi Win European Nod for RSV-Preventing Drug for Infants

MedCity News

AstraZeneca already has a respiratory syncytial virus antibody drug on the market for premature babies. But the approval of Beyfortus, which was developed with Sanofi, covers all infants broadly and it protects during the entire RSV season with just a single shot.

Marketing 129
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New evidence review uncovers ‘significant’ link between particulate matter and dementia

PharmaTimes

Information from 17 existing studies was reviewed, involving 91 million people

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While DCTs get all the hype, some industry insiders say the future is a digital hybrid

PharmaVoice

Leaders at Veeva believe the wording around decentralized trials has been exaggerated, and that a bigger-picture outlook is important as the pandemic winds down.

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How to Stay Competitive in the Evolving State of Martech

Marketing technology is essential for B2B marketers to stay competitive in a rapidly changing digital landscape — and with 53% of marketers experiencing legacy technology issues and limitations, they’re researching innovations to expand and refine their technology stacks. To help practitioners keep up with the rapidly evolving martech landscape, this special report will discuss: How practitioners are integrating technologies and systems to encourage information-sharing between departments and pr

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New therapy for anaemic myelodysplastic cancer patients

European Pharmaceutical Review

Bristol Myers Squibb (BMS) has announced Reblozyl ® (luspatercept-aamt), the first erythroid maturation agent, showed improvement in red blood cell transfusion independence (RBC-TI) and haemoglobin (Hb) increase in severely anaemic adults with very low, low or intermediate-risk myelodysplastic syndromes (MDS). Reblozyl is a first-line therapy that promotes late-stage red blood cell maturation in animal models.

Patients 105
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AMA: CMS’ 2023 Physician Fee Schedule Would Create ‘Financial Instability’

MedCity News

The 2023 Physician Fee Schedule conversion factor — which calculates how much a physician is reimbursed by Medicare for services — changed to $33.06, a $1.55 decrease from 2022 at $34.61. The American Medical Association strongly opposes the cuts.

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Roche’s Actemra gets Health Canada approval for Covid-19 treatment

Pharmaceutical Technology

Hoffmann-La Roche (Roche Canada) has received approval from Health Canada for Actemra IV (tocilizumab for injection) vials to treat Covid-19 patients. The treatment is indicated for adult Covid-19 patients who are on systemic corticosteroids and need additional oxygen, non-invasive or invasive mechanical ventilation, or extracorporeal membrane oxygenation.

Patients 105
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Streamlining Equipment Quality and Flexibility

PharmaTech

Data analytics, modular equipment, digital tools, and risk-based validation improve speed, flexibility, and quality.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time