Sat.Oct 08, 2022 - Fri.Oct 14, 2022

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Novel cancer therapeutic synthesised by Stanford researchers

European Pharmaceutical Review

Research published in the journal Nature Chemistry , shows how researchers from Stanford University in the US uncovered a promising new method to synthetically manufacture the compound tigilanol tiglate, named EBC-46, which could offer targeted medicine for cancer and other diseases. Natural sources of the compound can only be found in a small section of the Northeastern Australia rainforest, in fruit seeds from the blushwood tree ( Fontainea picrosperma ).

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How payers, employers can expedite healthcare’s transition to value-based care

MedCity News

Moving to value-based care models isn’t easy. But payers may be in the best position to make this change, according to the Business Group on Health. Employers, meanwhile, can encourage their employees to receive care from providers participating in value-based care.

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Janssen leads effort to cut waste in digital health devices

pharmaphorum

A consortium of industry and academic groups – led by Johnson & Johnson’s pharma division Janssen – has been set up to tackle the environmental impact of digital health products, specifically aimed at minimising waste that could end up in landfill. The Digital Health in a Circular Economy (DiCE) group was formed earlier this year with the aim of developing ways to “design, collect, directly reuse, refurbish, remanufacture, and recycle digital health devices.” The programme

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Patient recruitment completed in Tourette syndrome study

PharmaTimes

Research has demonstrated a strong safety prolife and reduced tics among participants

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AI Strategies for Sales Managers: How to Cut Down on Tedious Admin Work

What if you could help your sellers stop wasting 72% of their day on non-selling activities and focus on bringing in revenue? Incorporating AI in your enablement workflows can help you cut down on busy work, get projects done faster, and let your team (and you!) focus on making a bigger impact. We put together this guide to show you how to use AI to cut time and costs for projects, including collateral creation, development of training videos, and automating tedious processes.

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Robotic capsule could replace injected biologics

European Pharmaceutical Review

Scientists at MIT have demonstrated that a novel robotic capsule could potentially replace conventional biologic injection methods by tunnelling through the intestinal mucus barrier to deliver insulin. The research, published in the journal Science Robotics described how the new drug delivery system can transport large protein and small-molecule drugs, like vancomycin, an antibiotic peptide.

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Remote patient monitoring applications from cancer care to sleep [Sponsored]

MedCity News

In response to emailed questions, executives from Biofourmis, Force Therapeutics and Project Ronin shared products they’re developing in remote patient monitoring as part of the broader hospital at home trend.

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XBiotech enrols first patient in Natrunix study

PharmaTimes

Therapy involves patients with colorectal cancer at 20 medical centres

Patients 119
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RemeGen receives ODD for myasthenia gravis treatment

European Pharmaceutical Review

RemeGen has announced that the US Food and Drug Administration (FDA) has granted Orphan Drug Designation (ODD) for its proprietary novel fusion protein Telitacicept (RC18) for the treatment of myasthenia gravis (MG). Telitacicept is a proprietary novel fusion protein from RemeGen to treat autoimmune diseases. It is constructed with the extracellular domain of the human transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI) receptor and the fragment crystallisable

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Hackers are exploiting the very security tools providers use to protect themselves, HHS warns

MedCity News

Cybercriminals are weaponizing the same tools that healthcare providers use to operate and maintain secure IT systems, HHS warned in a recent report. Providers can protect themselves by having a firm grasp of what their IT environment looks like, as this may help them spot any suspicious security tool commands.

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Merck and Moderna partner to develop and sell cancer vaccine

Pharmaceutical Technology

German pharmaceutical firm Merck has extended its partnership with Moderna to jointly develop and sell mRNA-4157/V940, an investigational personalised cancer vaccine (PCV). In 2016, the companies entered a strategic partnership to develop novel messenger RNA (mRNA) based PCVs. They subsequently expanded the collaboration to include the development of antigen mRNA cancer vaccines in 2018.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Positive results from trial of Arecor’s insulin candidate AT247

PharmaTimes

Therapy demonstrates significantly accelerated insulin absorption and early exposure

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AstraZeneca’s intranasal COVID vaccine fails first clinical test

pharmaphorum

An intranasal formulation of AstraZeneca’s widely-used COVID-19 vaccine Vaxzevria has failed at the first hurdle, after results from a phase 1 trial found it was unable to stimulate a strong immune response to the virus. The 30-subject study – funded by AZ and published in the Lancet journal eBioMedicine – tested two strengths of the current formulation of the vaccine administered as a nasal spray, with half the group receiving a second intranasal dose 28 days later, and half getting a reg

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What you need to know about the New York State healthcare bonus program

MedCity News

While much of the world was quarantining and working from home during the Covid-19 pandemic, […].

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Video Games to Improve Cognition in Older Adults

Medgadget

Researchers at the University of California San Francisco have developed a suite of video games that have been designed to improve cognition in older adults who are otherwise healthy. The games aim to recreate common activities, such as banging a drum or driving a car. They also include a sophisticated algorithm that automatically adjusts the game difficulty depending on how well someone is playing, helping to stop less skilled players from becoming overwhelmed and more skilled players from beco

Training 115
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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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The digital therapeutics revolution is happening and Big Pharma is buying in — with caution

PharmaVoice

Companies like Pfizer, Novartis, Sanofi and BMS are diving into the world of digital therapeutics while recognizing the limitations of the young field.

Pharma 116
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PharmaLex?seals merger with UK’s NeoHealthHub

PharmaTimes

Agreement will be key to building a pan-European market access practice

Marketing 114
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5 steps to develop a dashboard to better manage your operations

MedCity News

How do organizations optimize and scale business intelligence? Here are five basic steps to consider when developing dashboards to assess your operational, financial and quality components within the care at home industry.

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Novel Devices to Help Surgeons Sculpt a New Ear

Medgadget

At Johns Hopkins, clinical researchers have developed a set of surgical tools that allow them to more easily create a replacement ear for those born with malformed or missing ears. Currently, using cartilage harvested from the ribs, surgeons can create a new ear, but the process is difficult and requires some artistic talent to sculpt the cartilage into the right shape.

Medicine 115
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Eureka Institute to show what translational medicine can do for digital health

pharmaphorum

It’s no secret that the healthcare system is made up of a panoply of diverse stakeholders, each with their own priorities, incentives, and motivations. Bringing those stakeholders together is an oft-lauded goal, but it’s proved easier said than done. The Eureka Institute, a Syracuse, Italy-based non-profit, is focused on addressing this disparity by providing education, research, and advocacy around the field of translational medicine.

Medicine 111
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AlzeCure demonstrates disease-modifying effects of NeuroRestore ACD856

PharmaTimes

Data from the study shows that ACD856 has a potential neuroprotective effect in a cellular mode

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Financing roundup: Neumora refuels, Ascidian ascends, Mablink’s moves & more

MedCity News

Odyssey Therapeutics raised $168 million in Series B financing, the largest round of funding for a biotech startup this week. Companies developing new technologies in genetic diseases, cancer, and drug research are represented also represented in this week’s recap of life science financings.

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FDA Expands Oversight of Cell and Gene Therapies

PharmaTech

CBER maps modernization plan to handle surge in research and applications.

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How to Prove Marketing Value: Demonstrate Content ROI and Contribution to Sales

Every marketer knows how important it is to prove their efforts drive sales opportunities, but that’s easier said than done. When problems like sales and marketing misalignment, lack of data, and wasted efforts persist, marketers can’t measure, prove, or increase their impact on revenue at a time when demonstrating marketing value is critical. Using analyst and expert data, this guide to marketing impact and content attribution explains: How B2B buyers use content The most common types of conten

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How the food allergy sector is benefitting from health tech’s recent boom

pharmaphorum

For the 32 million individuals in the US with food allergies, more research into symptoms, causes, and treatments has been long sought after, but historically underfunded. The National Institutes of Health (NIH), which oversees disease research, has a total annual budget equivalent to $120 per person, with only $0.19 per person being spent on food allergy research.

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Brainomix in collaboration with UK Government-funded NCIMI

PharmaTimes

Partnership will evaluate AI-powered technology in lung cancer care

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Providence denies ‘disturbing’ debt collection practices alleged by senator

MedCity News

Providence issued a response to a letter sent by Sen. Patty Murray of Washington, in which she demanded the health system answer questions about its alleged efforts to aggressively bill patients who qualified for free or discounted care. The response denied that Providence aggressively pursued its poorest patients for medical debt, asserting that its “commitment to those in need has never been stronger.”.

Medical 126
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Woman of the Week: HBA’s Nikki Jones

PharmaVoice

As the Healthcare Businesswomen’s Association’s first chief people and DEI officer, Jones is poised to tackle pay gap inequity, systemic gender bias and leadership barriers impeding women of color.

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How to Stay Competitive in the Evolving State of Martech

Marketing technology is essential for B2B marketers to stay competitive in a rapidly changing digital landscape — and with 53% of marketers experiencing legacy technology issues and limitations, they’re researching innovations to expand and refine their technology stacks. To help practitioners keep up with the rapidly evolving martech landscape, this special report will discuss: How practitioners are integrating technologies and systems to encourage information-sharing between departments and pr

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First FDA pregnancy-approved Pertussis vaccine to protect newborns

European Pharmaceutical Review

The US Food and Drug Administration (FDA) has approved GlaxoSmithKline Biologicals’ Boostrix vaccine for use in pregnant woman in their third trimester, to prevent against whooping cough (pertussis) in infants up to two months of age. Boostrix (Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed [Tdap]) boosts antibodies in individuals administered with the vaccine, which are then transferred to the growing foetus.

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3.2m UK birds culled as record avian flu cases increase

PharmaTimes

Virus can be lethal to humans and its spread is likely to accelerate this winter

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3 things providers should do to prepare for a potential railroad strike

MedCity News

A nationwide railroad strike could be coming mid-November. There are some key considerations that healthcare providers should take note of while they anticipate the possibility of a this strike, including having proactive conversations with their suppliers and identifying product alternatives.

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Odyssey Therapeutics $168 million Series B financing oversubscribed

pharmaphorum

Biotech company Odyssey Therapeutics, Inc. has announced a $168 million Series B financing, led by global venture capital firm General Catalyst, an active investor in the healthcare sector. The proceeds are to advance Odyssey’s precision immunomodulator and oncology medicine portfolio. The latest funding announcement follows the company’s $218 million Series A financing in December 2021 and brings the total capital raised to $386 million – enabling continuance of Odyssey’s mission to devel

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time