Sat.Oct 01, 2022 - Fri.Oct 07, 2022

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Healthcare’s entrance into the metaverse isn’t as intimidating as you may think

MedCity News

The metaverse holds promising potential to transform healthcare delivery for the better, according to a keynote talk delivered at MedCity’s Invest Digital Health conference. The speaker identified workforce training, patient experience, healthcare facilities and medical manufacturing as the main areas poised for disruption.

Training 145
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Meet Florence, WHO’s AI-powered digital health worker

pharmaphorum

An artificial intelligence-powered digital health worker has been unveiled by the World Health Organisation (WHO) as its latest tool for disseminating reliable health information to the public. Originally developed by New Zealand tech company Soul Machines with support of the Qatar Ministry of Health, the first version of the virtual health worker was used to combat misinformation about the pandemic.

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Provention and Sanofi enter deal to launch teplizumab for type 1 diabetes

Pharmaceutical Technology

Provention Bio and Sanofi US have signed a co-promotion agreement to launch the former’s lead investigational drug candidate, teplizumab for the delay in the onset of clinical type 1 diabetes (T1D). The agreement aids Provention in leveraging the capabilities and commercial resources of Sanofi to back teplizumab’s launch. The US Food and Drug Administration (FDA) is presently reviewing teplizumab for the delay of clinical T1D in people who are at risk.

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Growth in Cell and Gene Therapy Market

PharmaTech

Biopharma focuses on streamlining biomanufacturing and supply chain issues to drive uptake of cell and gene therapies.

Biopharma 143
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AI Strategies for Sales Managers: How to Cut Down on Tedious Admin Work

What if you could help your sellers stop wasting 72% of their day on non-selling activities and focus on bringing in revenue? Incorporating AI in your enablement workflows can help you cut down on busy work, get projects done faster, and let your team (and you!) focus on making a bigger impact. We put together this guide to show you how to use AI to cut time and costs for projects, including collateral creation, development of training videos, and automating tedious processes.

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CHESS Health launches substance use disorder recovery support app in Spanish

MedCity News

More than 7% of Hispanic Americans have a substance use disorder, but have less access to treatment than non-Hispanic Americans. The Spanish version of the app will provide the same services as English version, but with a focus on challenges experienced by the Latinx community.

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Merck’s Lagevrio ‘no better than placebo’ in COVID hospitalisations

pharmaphorum

A UK study has found that Merck & Co’s oral COVID-19 therapy Lagevrio was unable to reduce hospitalisations compared to placebo in patients at higher risk from the virus, adding fuel to assertions in some quarters that its authorisation was premature. The 25,000-subject PANORAMIC trial conducted by researchers at Oxford University looked at the addition of a five-day course of Lagevrio (molnupiravir) to standard care in people aged over 50, or adults aged 18 and over with conditions th

Patients 119

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How Novartis Sales Teams Drive Results with Personalized Videos to HCPs

Storyvine

CHALLENGE. In-person access to Health Care Providers (HCPs) was dramatically reduced due to COVID-19, and pharmaceutical sales reps struggled with gaining access and engagement even as things have “returned to normal.” This lack of face-to-face customer access had the potential to impact revenue, and Novartis wanted an innovative solution that would allow their Sales Associates to improve engagement and drive sales—and it needed to work in their highly-regulated environment.

Sales 111
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Google Cloud unveils medical imaging suite with Hologic, Hackensack Meridian as 1st customers

MedCity News

Google Cloud unveiled a new product suite to make medical imaging data more interoperable and useful via artificial intelligence. Hackensack Meridian Health has begun using it to detect metastasis in prostate cancer patients earlier, and Hologic is using it to strengthen its diagnostic platform that screens women for cervical cancer.

Medical 123
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Hollywood and the Metaverse’s effect on pharma’s content

pharmaphorum

Gaurav Kapoor, co-founder and executive vice president of Indegene, tells pharmaphorum how pharma can take lessons from the entertainment industry and prepare for the Metaverse to enhance content engagement. Pharma companies’ customer communication methods require reimagining as technology progresses. Kapoor says, now, pharma can learn from the on-demand nature of content distribution that Hollywood utilises and simultaneously prepare for future needs in content delivery. “One of our

Pharma 113
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High risk, high reward – the future of CAR-T therapy in CLL

Pharmaceutical Technology

In 2010, two patients with end-stage refractory chronic lymphocytic leukaemia (CLL) were administered Novartis’ autologous anti-CD19 chimeric antigen receptor T-cell (CAR-T) therapy, Kymriah (tisagenlecleucel), as part of a Phase I trial. In March this year, it was reported that these two patients were still in remission, making this the longest known CLL remission after CAR-T therapy and demonstrating to the industry that long-term remission is indeed possible.

Patients 111
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Conductive Cotton Thread for Wearable Sensors in Commercial Textiles

Medgadget

Imperial College London researchers created a conductive cotton thread that can undergo a computerized embroidery process for incorporation into commercially produced textiles, such as t-shirts and face masks. The thread, called PECOTEX, can be used to create wearable health sensors, such as heart rate monitors, breathing monitors and even gas sensors, including ammonia sensors for the breath, which can provide information on liver and kidney function.

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Zoom’s impact on intercontinental startup investment

MedCity News

An INVEST Digital Health panel discussion on investment beyond the traditional hubs of venture capital investment, touched on the role of Zoom in making it easier to maintain relationships with startups across the country in places like Indiana, Utah, Colorado and beyond.

Biopharma 131
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CAR-T therapy safe for relapsed or refractory T-cell malignancies, finds study

European Pharmaceutical Review

Bioheng Biotech , a biotechnology firm that develops cellular immunotherapies, have issued key Phase I clinical trial (NCT04538599) results for the drug RD13-01, an anti-CD7 universal CAR-T therapy, establishing that it is safe for use and has the potential to eliminate malignant tumours. It is the first trial to use healthy donor-derived CD7-targeting allogeneic CAR T cells to treat CD7-positive haematological tumours.

Safety 109
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Pfizer acquires biopharma firm Biohaven for $11.6bn

Pharmaceutical Technology

Pfizer has acquired commercial-stage biopharmaceutical firm Biohaven Pharmaceutical for $148.50 for each share or a total consideration of nearly $11.6bn in cash. In May, Pfizer entered a definitive agreement to acquire all outstanding shares of Biohaven which were not previously held by the former. . With the takeover, Biohaven became a wholly-owned Pfizer subsidiary.

Biopharma 106
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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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DNA Nets Capture Sars-CoV-2 for Detection and Inhibition

Medgadget

A team at the University of Illinois at Urbana-Champaign has developed a DNA net system that can ensnare Sars-CoV-2 and bind to the notorious spike protein. The nets contain aptamers that bind the spike protein and emit an intense fluorescent signal once they’re bound together to the protein. This signal can be easily measured using a handheld fluorimeter.

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Mental health startup for seniors rakes in $32M from General Catalyst, Mass General, others

MedCity News

There is a dearth of professionals with licenses and training to provide care for seniors’ mental and behavioral health challenges — such as Alzheimer’s and other dementias, anxiety and depression. Seattle-based Rippl Care is seeking to change this. The startup just closed a $32 million seed funding round led by ARCH Venture Partners and General Catalyst.

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Calcium Focuses on Race and Healthcare with “I DON’T HAVE A BOX” Campaign

PM360

Arising out of Calcium’s DEI initiatives, the healthcare marketing agency has launched the “I DON’T HAVE A BOX” campaign to drive awareness of the “race box” used in health data collection and its shortcomings in capturing true racial and ethnic diversity. Initially launched via website and social media, the campaign’s objective is to stimulate conversations around racial and ethnic “blind spots” in the healthcare system, ultimately translating into institutional change and improved health equit

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European Commission’s approval of Mounjaro provides hope within obesity space

Pharmaceutical Technology

The type 2 diabetes (T2D) space recently witnessed a new approval: on 15 September, the European Commission (EC) authorised Eli Lilly’s Mounjaro (tirzepatide) for T2D patients. Mounjaro is a dual gastric inhibitory polypeptide (GIP)/glucagon-like peptide 1 (GLP-1) receptor agonist. This event is of paramount interest, and not only for T2D patients, as it could address vital unmet needs for other GIP/GLP-1 receptor agonist–treated diseases, including obesity.

Safety 105
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Pilot to support ATMP research and development

European Pharmaceutical Review

The European Medicines Agency (EMA) is set to launch a pilot aimed at helping advanced therapy medicinal product (ATMP) scientists navigate the regulatory challenges throughout the research process: from initial investigation to the development of medicines, to support non-profit’s solve unmet clinical needs and progress ground-breaking research for EU patients.

Medicine 105
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Cybersecurity mesh: Healthcare’s foundation for a strong ZTA

MedCity News

One of the most popular analyst terms in 2022, cybersecurity mesh is a defense method for securing each device and critical access points with their own security perimeter. It builds a foundation of dynamic interoperability in the environment, rather than the traditional security protections of a single perimeter.

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Soft Robot Grows Like a Plant to Travel Through Tight Spaces

Medgadget

At the University of Minnesota, researchers have developed a soft robotic system that can ‘grow’ like a plant. The mechanism allows it to travel through difficult-to-access areas, such as the tortuous gastrointestinal tract or vasculature. The system works by extruding a liquid through an opening in the device, and at the same time a photopolymerization process results in the rapid solidification of the liquid into a solid structure.

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UK NICE recommends zanubrutinib for Waldenstrom’s macroglobulinaemia

Pharmaceutical Technology

The UK National Institute for Health and Care Excellence (NICE) has recommended zanubrutinib (Brukinsa) as an option to treat Waldenstrom’s macroglobulinaemia (WM) patients. With the latest development, zanubrutinib became the first WM drug to receive the recommendation for routine National Health Service (NHS) usage in England. The recommendation will also be applicable in Wales and Northern Ireland.

Patients 105
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How to Prove Marketing Value: Demonstrate Content ROI and Contribution to Sales

Every marketer knows how important it is to prove their efforts drive sales opportunities, but that’s easier said than done. When problems like sales and marketing misalignment, lack of data, and wasted efforts persist, marketers can’t measure, prove, or increase their impact on revenue at a time when demonstrating marketing value is critical. Using analyst and expert data, this guide to marketing impact and content attribution explains: How B2B buyers use content The most common types of conten

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Collaborations between pharma and academia increase

European Pharmaceutical Review

The Association of the British Pharmaceutical Industry (ABPI)’s survey identified that the sector is helping industry entrants by embracing hands-on training methods such as apprenticeships, degree placements, PhDs and post-doctoral researcher awards, with data showing that apprentices being trained by pharmaceutical companies is the highest on record.

Pharma 104
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Biotech IPO market slowdown continues as third quarter is weakest since 2011

MedCity News

Third Harmonic Bio’s stock market debut was the only biotech IPO that crossed the $100 million threshold in the third quarter as the slowdown in IPO activity showed little sign of changing. Small deals continue to represent most of the IPO activity.

Marketing 117
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Solid Biosciences acquires AavantiBio, conducts $75 million private placement

pharmaphorum

The life sciences company Solid Biosciences is merging with the privately-held gene therapy company AavantiBio in a deal which is expected to result in a combined sum of $215 million in cash and investments – projected to be enough for funding into 2025. AavantiBio, a precision genetic medicine company that was bankrolled by Solid’s rival Sarepta back in 2020, focuses on neuromuscular and cardiac rare diseases.

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US FDA grants Fast Track status for Lilly’s tirzepatide to treat obesity

Pharmaceutical Technology

The US Food and Drug Administration (FDA) has granted Fast Track designation for Eli Lilly and Company ’s tirzepatide to treat adults with obesity or overweight with weight-associated comorbidities. . On holding talks with the regulatory agency, the company intends to commence a rolling submission of a new drug application (NDA) for tirzepatide in adults for this indication this year.

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How to Stay Competitive in the Evolving State of Martech

Marketing technology is essential for B2B marketers to stay competitive in a rapidly changing digital landscape — and with 53% of marketers experiencing legacy technology issues and limitations, they’re researching innovations to expand and refine their technology stacks. To help practitioners keep up with the rapidly evolving martech landscape, this special report will discuss: How practitioners are integrating technologies and systems to encourage information-sharing between departments and pr

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Quantifying proteins en masse using coulometric mass spectrometry

European Pharmaceutical Review

Researchers from the New Jersey Institute of Technology (NJIT), US, have developed a pioneering technique to test and produce new protein-based drugs, like therapeutic monoclonal antibodies (mAbs), which could help scientists develop better solutions to globally problematic diseases such as cancers and infectious illnesses. . The electrochemistry-based technique, recorded in the journal Analytical Chemistry , actively monitors the efficacy and safety of therapeutic protein components throughout

Safety 103
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A preview of INVEST 2023: Themes and networking opportunities revealed

MedCity News

Save the date for INVEST 2023, which will take place on May 22-24 at the Ritz Carlton hotel in Chicago. The conference unites novel startups with active investors, highlights payer and provider perspectives, identifies challenges and opportunities in the life sciences, and describes healthcare’s overall transformation.

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Roche gets FDA approval for HER2 breast cancer diagnostic

pharmaphorum

The FDA has approved Swiss pharmaceutical company Roche’s first companion diagnostic for identifying those patients with HER2 low-metastatic breast cancer who are eligible for ENHERTU. The approval brings hope to many, with breast cancer having surpassed lung cancer to become the most commonly diagnosed cancer in the world: there are approximately 2.3 million new cases each year, and each year over 620,000 breast cancer patients will die.

FDA 103
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CCC Honored as Gold Winner in Customer Service Department of the Year Category From the Best in Biz Awards 2022 International

Copyright Clearance Center

The post CCC Honored as Gold Winner in Customer Service Department of the Year Category From the Best in Biz Awards 2022 International appeared first on Copyright Clearance Center.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time