Sat.Sep 17, 2022 - Fri.Sep 23, 2022

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First patient dosed with HIV gene therapy

European Pharmaceutical Review

A breakthrough gene-editing therapy for human immunodeficiency virus type 1 (HIV) infection has entered first-in-human testing in what is being called “a major milestone in the search for a cure for HIV/AIDS”. EBT-101, a CRISPR-Cas9 gene editing system delivered by adenovirus-associated virus vector serotype 9 (AAV9) has been administered to the first individual in a Phase I/II trial designed to establish its safety and efficacy.

Patients 145
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Micro-robots, smart toilets, and 3D bioprinted organs: the future of healthcare

Pharmaceutical Technology

It is the year 2030. You have just received the results from your whole genome sequencing test, offered through your public health provider, and discovered that you have a 75% chance of developing a rare form of cancer. But you are not panicking; your genomic data was automatically uploaded, with your permission, to your electronic health record (EHR), which is fully secured with blockchain technology.

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Med-tech and health facilities: A cybersecurity house of mirrors

MedCity News

Much like a house of mirrors, responsibility for understanding and mitigating cyber risk in healthcare is difficult to distinguish and often depends on who you ask, especially when it comes to non-enterprise systems and devices.

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Customer engagement and content strategies for pharma’s commercial operations

Dominic Tyer

Moving from the ‘new normal’ to the ‘next normal’ and beyond, the landscape for pharma’s commercial operations continues to shift, with all stakeholders beginning to adjust to a post-pandemic world

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AI Strategies for Sales Managers: How to Cut Down on Tedious Admin Work

What if you could help your sellers stop wasting 72% of their day on non-selling activities and focus on bringing in revenue? Incorporating AI in your enablement workflows can help you cut down on busy work, get projects done faster, and let your team (and you!) focus on making a bigger impact. We put together this guide to show you how to use AI to cut time and costs for projects, including collateral creation, development of training videos, and automating tedious processes.

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Genetically modified herpes combats advanced cancers

PharmaTimes

A new genetically engineered virus has delivered a one-two punch in initial phase 1 trial

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Sales Leadership Skills That Will Help Your Team Soar to New Heights

Integrity Solutions

Growing a sales team isn’t hard. Growing a sales team that’s confident, comfortable and successful in their role… now that’s a challenge. The effectiveness of any sales team starts with the sales leaders. It’s why many experts say any L&D spending should start (not end) with investing in your leaders. Simply adding more people to the team won’t deliver the scalability and dividends you’re looking for if your sales leaders aren’t willing to put

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Pfizer to deliver up to six million courses of Paxlovid to Global Fund

Pharmaceutical Technology

Pfizer has entered an agreement with Global Fund to deliver up to six million courses of its oral therapy, Paxlovid (nirmatrelvir tablets and ritonavir tablets), under the Covid-19 Response Mechanism (C19RM). The C19RM has been the main channel to support low- and middle-income nations in procuring Covid-19 therapies, personal protective equipment, tests and vital elements to bolster health systems.

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AstraZeneca’s Tezspire for severe asthma gets green light in EU

pharmaphorum

The European Commission has followed the lead of the US FDA and approved AstraZeneca’s Tezspire as an add-on maintenance therapy for patients with severe asthma, becoming the first and only biologic that can be used in all patients, and not restricted to those with specific forms of the disease. Tezspire (tezepelumab) has been cleared for use in patients 12 years and older with severe asthma who are inadequately controlled with high dose inhaled corticosteroids plus another medicinal produ

Sales 111
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Citation Laureates 2022: Nobel class researchers who are changing the world

Clarivate

Clarivate draws on Web of Science publication and citation data to produce an annual list of Citation Laureates – researchers of Nobel class whose high-impact contributions have transformed their fields and changed our world for the better. Every October, the world watches as the Nobel Assembly votes to confer their prestigious prizes. While people around the globe can’t help but speculate about who will be chosen, Clarivate is the only organization to use quantitative data in addition to qualit

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Lab testing transparency will improve patient care and lower costs

MedCity News

As the U.S. healthcare industry continues to advance value-based care and population health, lab testing price transparency and payment integrity programs should be a priority.

Patients 126
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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EMA CHMP recommends authorisation of AstraZeneca’s Evusheld for Covid-19

Pharmaceutical Technology

The European Medicines Agency’s (EMA) Committee for Medicinal Products for Human Use (CHMP) has recommended granting marketing authorisation for AstraZeneca ’s Evusheld (formerly AZD7442) for Covid-19 in the European Union (EU). This therapy is intended to treat adult and adolescent Covid-19 patients aged 12 years and above, who do not need additional oxygen and are at greater disease progression risk.

Medicine 111
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Hope for lupus sufferers with Feinstein Institutes-led phase 2 trial

pharmaphorum

Findings from the litifilimab trial, undertaken by Northwell Health’s Division of Rheumatology and The Feinstein Institutes for Medical Research, have been published in the New England Journal of Medicine and show promise for those who have been diagnosed with systemic lupus erythematosus (SLE). Sponsored by Biogen Inc., data from the phase 2 LILAC (Part A) clinical trial published this month shows that the experimental lupus therapy could reduce disease activity in the joints of patients, globa

Medicine 111
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LumiraDx Partners with British In Vitro Diagnostics Association

PharmaTimes

Link up will involve reporting on role of rapid diagnostics in taking on antimicrobial resistance

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Humanizing the digital experience in healthcare

MedCity News

These are the three changes health-tech needs to make to recreate Amazon, Uber or Venmo-like experiences in healthcare that will most accurately help to digitally replicate the humanized interactions that patients want:

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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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Face Mask Detects Respiratory Viruses, Alerts User

Medgadget

Scientists at Shanghai Tongji University in China have created a face mask that can alert the wearer to the presence of respiratory viruses in the surrounding environment, including the viruses behind COVID-19 and influenza. The mask includes aptamers, which are short sequences of DNA or RNA that can bind to protein targets. When viral particles bind to the aptamers, ion-gated transistors boost the signal so that the mask can sensitively detect small amounts of virus.

Media 108
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GSK requires supplier sustainability compliance from 2023

European Pharmaceutical Review

At Climate Week NYC GSK presented its new Sustainable Procurement Programme, announcing a fresh agenda, outlining how they will support their suppliers to succeed in their bold environmental objectives: have a net zero climate impact and a net positive impact on nature. This is an important move, as many GSK suppliers do not have easy geographical access to green infrastructure or green financing.

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10 Ways to Attract New Patients from Key Local Employers

Healthcare Success

Help Providers Win New Patients from Large Local Businesses with These Tactics. Large or dominant employers in your local communities are excellent targets of opportunity for new patients and cases. Most healthcare providers have local businesses that are (or could be) a source of new business. Whether it’s a company that's conveniently located across the street, or a dominant employer in the community, your providers want their business—here’s how you can help them win it.

Patients 104
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Biogen bolsters case for ALS drug under FDA review with new published data

MedCity News

A Biogen drug designed for a genetically defined form of amyotrophic lateral sclerosis led to patient improvement at a 12- month analysis, according to data now published in the New England Journal of Medicine. Biogen had already filed an application seeking FDA approval of the ALS drug, tofersen; a regulatory decision is expected by January.

FDA 124
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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MSD’s pembrolizumab therapy gets NICE approval

PharmaTimes

1,500 people set to receive new skin cancer treatment that reduces the risk of it returning

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Green HPLC method enables antipsychotic determination

European Pharmaceutical Review

In a recent paper, researchers demonstrated the comparability of a green high performance liquid chromatography (HPLC) for the determination and screening of typical antipsychotic drugs both in bulk and pharmaceutical formulation. Antipsychotics are used to treat a variety of serious mental disorders including schizophrenia and bipolar disorder, in which manic states may require management with multiple drugs.

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PM360 Announces Winners of 2022 Trailblazer Awards

PM360

NEW YORK, NY, September 23, 2022: PM360 , a leading life sciences marketing industry trade publication, announced the winners of their 14 th annual Trailblazer Awards during an event held at Gotham Hall in New York City on Thursday, September 22, 2022. The awards recognize outstanding companies, CEOs, products, marketers, brand managers, and cutting-edge initiatives within the pharmaceutical, biotech, medical device, and diagnostics industries.

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M&A mania: Employers are concerned about constant healthcare consolidation, expert says

MedCity News

Cheryl Larson, president and CEO of Midwest Business Group on Health, said employers are worried that the consolidation of healthcare companies will lead to higher costs for employers and patients. She made her comments following McKesson’s announcement that it has agreed to acquire Rx Savings Solutions, but declined to speak specifically about the deal.

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How to Prove Marketing Value: Demonstrate Content ROI and Contribution to Sales

Every marketer knows how important it is to prove their efforts drive sales opportunities, but that’s easier said than done. When problems like sales and marketing misalignment, lack of data, and wasted efforts persist, marketers can’t measure, prove, or increase their impact on revenue at a time when demonstrating marketing value is critical. Using analyst and expert data, this guide to marketing impact and content attribution explains: How B2B buyers use content The most common types of conten

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For Banned Books Week 2022, A Record Year

Copyright Clearance Center

The post For Banned Books Week 2022, A Record Year appeared first on Copyright Clearance Center.

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NICE says yes to BeiGene’s Brukinsa after Scottish nay

pharmaphorum

BeiGene’s BTK inhibitor Brukinsa (zanubrutinib) has become the first drug in the class to be recommended for routine NHS use in England and Wales to treat Waldenström macroglobulinaemia (WM) – a rare form of non-Hodgkin lymphoma (NHL). The final appraisal document from health technology assessment (HTA) agency NICE says that Brukinsa can be used to treat WM in adults who have had at least one prior treatment, and only if bendamustine plus rituximab therapy is also suitable.

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EMA human medicines committee (CHMP) highlights, September 2022

European Pharmaceutical Review

In its first meeting since July, the European Medicines Agency (EMA)’s Committee for Medicinal Products for Human Use (CHMP) recommended these 12 medicines for approval: Beyfortus (nirsevimab) for the prevention of respiratory syncytial virus (RSV) lower respiratory tract disease in newborns and infants during their first RSV season (when there is a risk of RSV infection in the community).

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Cigna extends coverage for Brainsway’s brain stimulation device to treat OCD

MedCity News

Israeli medical device company Brainsway earned a positive coverage policy from Cigna for its deep transcranial magnetic stimulation to treat adult patients with OCD. Cigna joins the ranks of other major insurers who cover the device for OCD treatment — including Centene, Highmark, Blue Cross Blue Shield, Tricare and Palmetto GBA.

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How to Stay Competitive in the Evolving State of Martech

Marketing technology is essential for B2B marketers to stay competitive in a rapidly changing digital landscape — and with 53% of marketers experiencing legacy technology issues and limitations, they’re researching innovations to expand and refine their technology stacks. To help practitioners keep up with the rapidly evolving martech landscape, this special report will discuss: How practitioners are integrating technologies and systems to encourage information-sharing between departments and pr

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Research Results, Replicability, & Retractions

Copyright Clearance Center

As with my earlier post in this series on the overall role of peer review in the scholarly and scientific publishing process, for Peer Review Week 2022 we are reposting our pieces in this series. And little bit of updated information on the topics we covered: * Psychology, in particular, seems to have a replicability problem ; even outside of psych, everyone knows that bad papers are still getting published (and they may even have a discoverability advantage ). * Retraction Watch is still engage

Doctors 98
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Is Your Demand Side Platform (DSP) Ready for the Cookieless Future?

PharmExec

A cookieless future is on the horizon, so marketers across all industries are being forced to rethink their strategies and plan for the future. What does that entail?

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Patient centricity is becoming business critical for pharma

pharmaphorum

New book sets the pharmaceutical industry on a course for bridging the patient centricity optimism gap. Bridging the gulf between patient centricity ambition and reality has never been more important for pharma – luckily, this seemingly insurmountable goal isn’t as far out of reach as many envision. That’s according to Sharon Suchotliff, patient centricity lead at consultancy firm ZS Associates, which has just published a book on the art of patient involvement.

Pharma 98
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Healthcare investor shares what he wishes more startups did

MedCity News

Parth Desai, a principal with Flare Capital Partners, is one of three investor judges taking part in the Pitch Perfect competition at the INVEST Digital Health conference in Dallas September 28. He shares his perspective on the firm’s investment strategy, collaborating with startups, and more. Register today!

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time