Sat.Feb 11, 2023 - Fri.Feb 17, 2023

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GSK was warned repeatedly about Zantac impurity but played down risks: Bloomberg

Fierce Pharma

GSK was warned repeatedly about Zantac impurity but played down risks: Bloomberg esagonowsky Wed, 02/15/2023 - 09:02

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Virtual reality training in pharma: just a headset away?

European Pharmaceutical Review

The COVID-19 pandemic led to an unparalleled paradigm shift in the use of and the incorporation of new technologies into our workflows. This was particularly apparent in academia and the pharmaceutical industry, where we have seen words such as Teams and Zoom becoming part of our new lexicon of language for meetings. Now we reach for these types of online meetings without a second thought, due to the clear productivity benefits they provide over real in-person meetings. 1 However, notwithstandin

Training 144
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Healthcare and Gen X: 4 Things Marketers Need to Get Right

MedCity News

Gen X is at the height of its spending potential. Its U.S. population of 65 million has saved a collective $13 trillion and owns 29% of the nation’s household wealth (versus just 6.4% owned by millennials).

Marketing 142
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3D Bioengineered Skin Grafts Fit Complex Anatomy

Medgadget

Researchers at Columbia University’s Irving Medical Center have developed a method to create three-dimensional bioengineered skin grafts. To date, bioengineered skin is typically created in flat sheets. However, these are difficult to fit to complex anatomy, such as the hand, and so these researchers have designed a more sophisticated technique that combines laser scanning, 3D printing, and cell culture to create seamless three dimensional skin grafts.

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AI Strategies for Sales Managers: How to Cut Down on Tedious Admin Work

What if you could help your sellers stop wasting 72% of their day on non-selling activities and focus on bringing in revenue? Incorporating AI in your enablement workflows can help you cut down on busy work, get projects done faster, and let your team (and you!) focus on making a bigger impact. We put together this guide to show you how to use AI to cut time and costs for projects, including collateral creation, development of training videos, and automating tedious processes.

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Pfizer CEO's texts with European Commission chief trigger new NYT lawsuit

Fierce Pharma

Pfizer CEO's texts with European Commission chief trigger new NYT lawsuit kdunleavy Tue, 02/14/2023 - 10:29

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European Commission awards €7.7 million to mechanochemistry project

European Pharmaceutical Review

The European Commission (EC) has awarded IMPACTIVE almost €7.7 million to study the possibilities of mechanochemistry in the synthesis of active pharmaceutical ingredients (APIs). The ‘green’ project is a collaboration led by the University of Montpellier, in France. It is anticipated to reinvent and reinforce the pharmaceutical supply chain. The mechanochemistry initiative is funded by Horizon Europe and works with 17 partners in academia and industry working together towards greener chemistry.

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Ingestible Sensor Reveals Gastric Motility

Medgadget

Researchers at MIT have developed an ingestible sensor that can reveal gastrointestinal motility issues, such as gastroparesis and gastroesophageal reflux disease. The technology is intended for use as an easy at-home method to diagnose such issues, which typically require more invasive and inconvenient procedures, such as endoscopy or X-ray imaging.

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ASCO: Takeda's Iclusig shows potential to become standard of care in acute lymphoblastic leukemia subtype

Fierce Pharma

ASCO: Takeda's Iclusig shows potential to become standard of care in acute lymphoblastic leukemia subtype kdunleavy Tue, 02/14/2023 - 14:33

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How epilepsy researchers are moving the needle past anti-seizure treatments

Pharmaceutical Technology

While several therapeutics are available for treating symptoms associated with epilepsy, researchers and patients have strongly called out the need for more holistic treatments that would address the condition as a whole. Although recently approved drugs can treat seizures more safely, they do not treat the comorbidities that patients experience. Several biotech companies and researchers are now exploring medical devices and gene therapies to address not just common forms of epilepsy, but also r

Patients 105
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Decline of Telehealth During the Pandemic and After

MedCity News

Telehealth has been an essential tool during the pandemic but recent data shows that its utilization is decreasing as we move into 2021 and beyond. This decrease could lead to increased costs and decreased efficiency for healthcare systems as well as decreased access and poorer health outcomes for patients if nothing is done about it soon.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Automated Feeding Platform to Study Mosquito Disease Transmission

Medgadget

A team at Rice University has developed an automated feeding platform for mosquitoes that allows researchers to test different types of repellent and investigate mosquito-borne disease transmission. Traditionally, such mosquito research would require human volunteers or animal subjects for the mosquitos to feed on, but this is obviously inconvenient and a little distasteful.

Medicine 107
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Merck, Glenmark headed to trial after judge scraps early dismissal bid in Zetia antitrust case

Fierce Pharma

Merck, Glenmark headed to trial after judge scraps early dismissal bid in Zetia antitrust case fkansteiner Tue, 02/14/2023 - 10:38

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Analytical platform could advance mRNA medicine QC

European Pharmaceutical Review

Tokyo researchers have developed a new analytical platform based on liquid chromatography, mass spectrometry and software analysis that quantifies the structure of messenger RNA (mRNA)-based medicines. The method is an important innovation for quality control ( QC) in production lines. The platform can elucidate mRNA sequences while quantifying ‘capping’ at one end of the molecule and the integrity of the tail on the other, all vital in mRNA pharmaceuticals.

Medicine 105
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Is Interoperability Tech Worth the Investment? Experts Say Yes for 3 Reasons

MedCity News

Panelists at a recent healthcare conference expressed optimism about the automation technology that health plans, pharmacy benefit managers and providers can adopt to facilitate real-time data sharing. They said that such technology has potential to improve medication adherence, reduce costs and save time for both providers and payers.

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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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Brian Fox is bringing ‘fresh eyes’ to ad agency Klick

PharmaVoice

Why the recently appointed president of commercial solutions sees near limitless potential to expand Klick’s footprint across the life sciences — and how generative AI is playing a role.

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Apellis wins FDA approval for first geographic atrophy drug

Fierce Pharma

Apellis wins FDA approval for first geographic atrophy drug fkansteiner Fri, 02/17/2023 - 18:06

FDA 284
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Pfizer and BioNTech mRNA shingles vaccine study begins

European Pharmaceutical Review

Pfizer Inc. and BioNTech SE have announced the start of a Phase I/II trial for the companies’ mRNA vaccines for shingles (Herpes Zoster), for which there is no currently approved vaccine. Without vaccination, about half of the people who live to age 85 are expected to develop shingles, stated BioNTech. Both the incidence and severity of shingles rise with age, the company acknowledged.

Safety 105
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Rising Costs Are Keeping Healthcare CFOs Up a Night — Can Data Help?

MedCity News

The increasing costs of labor and supplies are the top issues keeping healthcare CFOs up at night, according to a new report. Even though providers’ margins are currently quite tight, the report recommended that healthcare organizations adopt data analytics software to remedy these concerns and help with important decisions like how to effectively manage their existing workforce and where to shift care delivery models.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Leading innovators in kidney disorder treatment compositions for the pharmaceutical industry

Pharmaceutical Technology

The pharmaceutical industry continues to be a hotbed of innovation, with activity driven by the evolution of new treatment paradigms, and the gravity of unmet needs, as well as the growing importance of technologies such as pharmacogenomics, digital therapeutics, and artificial intelligence. In the last three years alone, there have been over 633,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Innovation in Pharmaceuticals: Kidney disorder treatm

Leads 105
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Ahead of next month's FDA decision, Emergent aces AdComm for over-the-counter Narcan nod

Fierce Pharma

Ahead of next month's FDA decision, Emergent aces AdComm for over-the-counter Narcan nod fkansteiner Thu, 02/16/2023 - 14:12

FDA 265
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Key developments: mRNA vaccines and therapeutics

European Pharmaceutical Review

Recently there have been several key advances in the clinical development of messenger RNA (mRNA) vaccines, including vaccines for RSV and a personalised cancer vaccine. Since the COVID-19 pandemic, the industry has seen a spike in interest in mRNA therapeutics, due to the success of mRNA vaccines treating the virus, observed GlobalData. Initially developed to treat viral infections, mRNA vaccines deliver a piece of genetic material that instructs the body to make a protein fragment of a target

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How to Rein in Unpredictability During High-Traffic Respiratory Illness Season

MedCity News

Making operational changes to ease the unpredictable nature of respiratory season is the right thing to do for staff, for patients, and for the business. Digital solutions and better processes allow staff to work smarter and faster and prepare them for high-volume days ahead of time so they feel in control.

Patients 116
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How to Prove Marketing Value: Demonstrate Content ROI and Contribution to Sales

Every marketer knows how important it is to prove their efforts drive sales opportunities, but that’s easier said than done. When problems like sales and marketing misalignment, lack of data, and wasted efforts persist, marketers can’t measure, prove, or increase their impact on revenue at a time when demonstrating marketing value is critical. Using analyst and expert data, this guide to marketing impact and content attribution explains: How B2B buyers use content The most common types of conten

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Innovation in immuno-oncology: Leading companies in cancer monoclonal antibody therapy

Pharmaceutical Technology

The pharmaceutical industry continues to be a hotbed of innovation, with activity driven by the evolution of new treatment paradigms and the gravity of unmet need, as well as the growing importance of technologies such as pharmacogenomics, digital therapeutics, and artificial intelligence. In the last three years alone, there have been over 633,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Immuno-oncology: Leading companies in cancer monoclonal

Leads 104
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After J&J's Texas two-step stumble, another talc plaintiff heads to trial: report

Fierce Pharma

After J&J's Texas two-step stumble, another talc plaintiff heads to trial: report fkansteiner Wed, 02/15/2023 - 11:10

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Enzyme replacement therapy for alpha-mannosidosis gets FDA approval

European Pharmaceutical Review

The US Food and Drug Administration (FDA) has approved Lamzede ® (velmanase alfa-tycv) for non-central nervous system manifestations of alpha-mannosidosis (AM) in adult and paediatric patients. AM is an ultra-rare, progressive lysosomal storage disorder caused by deficiency in the enzyme α-mannosidase. Giacomo Chiesi, Head of Chiesi Global Rare Diseases stated that symptoms of the disorder include “impaired hearing, speech and mobility that progress from childhood into adulthood.

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Chiesi Wins FDA Approval for First Drug to Treat Ultra-Rare Enzyme Deficiency

MedCity News

Chiesi drug Lamzede is an engineered version of an enzyme that’s lacking in patients with the rare disease alpha-mannosidosis. FDA approval of the Chiesi drug comes about five years after European regulators authorized the product.

FDA 113
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How to Stay Competitive in the Evolving State of Martech

Marketing technology is essential for B2B marketers to stay competitive in a rapidly changing digital landscape — and with 53% of marketers experiencing legacy technology issues and limitations, they’re researching innovations to expand and refine their technology stacks. To help practitioners keep up with the rapidly evolving martech landscape, this special report will discuss: How practitioners are integrating technologies and systems to encourage information-sharing between departments and pr

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Acoustic Stimulation for Insomnia

Medgadget

Researchers at Wake Forest University School of Medicine have tested a closed-loop acoustic stimulation neurotechnology in its ability to treat insomnia. The device in question has been developed by Cereset , a medtech company headquartered in Arizona. Insomnia is not just unpleasant, but can have significant long-term health consequences, including an increased risk of cardiovascular disease, obesity, and diabetes.

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As HQ move nears completion, Merck finds a buyer for its sprawling Kenilworth campus

Fierce Pharma

As HQ move nears completion, Merck finds a buyer for its sprawling Kenilworth campus fkansteiner Fri, 02/17/2023 - 14:41

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Neoadjuvant nivolumab improves long-term survival for lung cancer

European Pharmaceutical Review

Final analyses of a Phase II trial for resectable non-small cell lung cancer (NSCLC) has concluded that 60 percent of patients treated with neoadjuvant nivolumab remained recurrence-free five years after surgery. Improved overall survival rates compared with historical outcomes were also observed. The results suggest “that neoadjuvant nivolumab was safe in long-term follow-up,” commented Patrick Forde, MBBCh, an Associate Professor of oncology and Director of the Thoracic Oncology Clinical Resea

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Elation Health Buys Medical Billing Company to Create All-in-One Tech Platform for Primary Care Providers

MedCity News

Elation Health announced its acquisition of medical billing company Lightning MD — a deal the company made to help it become an all-in-one technology platform for primary care providers. Lighting MD stood out from other medical billing startups because of its ease of use, Elation CEO Kyna Fong said.

Medical 115
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European Clinical Supply Planning: Balancing Cost, Flexibility and Time