Sat.Apr 15, 2023 - Fri.Apr 21, 2023

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Goodbye, original COVID-19 vaccines: FDA updates shot guidance, pulls monovalent authorizations

Fierce Pharma

Goodbye, original COVID-19 vaccines: FDA updates shot guidance, pulls monovalent authorizations zbecker Wed, 04/19/2023 - 11:04

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A CMO’s quest to tackle infectious diseases leads him to an eye condition that’s often overlooked

PharmaVoice

How an “international” childhood sent Dr. José Trevejo, Tarsus’s chief medical officer, on a mission to fight infectious diseases.

Leads 98
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Nanoparticles Deliver mRNA Therapy to the Lungs

Medgadget

Researchers at MIT have developed lipid nanoparticles that are highly efficient at delivering mRNA therapies to lung cells. Getting therapeutic agents into the lungs can be challenging, but there are a variety of medical challenges that could be addressed by efficiently targeting lung cells with nanoparticle technologies. These latest particles are highly efficient at delivering mRNA which can then encode therapeutically useful proteins in the lungs.

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Innovaccer Launches Conversational AI Assistant to Help Health System, Payer Execs

MedCity News

Innovaccer launched a new product called Sara, a conversational AI assistant designed to help executives at health systems and payers make better use of their data. It allows executives can ask complex questions about their organization’s patients or members and get immediate answers on clinical, financial or operational metrics.

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AI Strategies for Sales Managers: How to Cut Down on Tedious Admin Work

What if you could help your sellers stop wasting 72% of their day on non-selling activities and focus on bringing in revenue? Incorporating AI in your enablement workflows can help you cut down on busy work, get projects done faster, and let your team (and you!) focus on making a bigger impact. We put together this guide to show you how to use AI to cut time and costs for projects, including collateral creation, development of training videos, and automating tedious processes.

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In heavyweight obesity fight, Eli Lilly launches Mounjaro head-to-head trial against Novo Nordisk's Wegovy

Fierce Pharma

In heavyweight obesity fight, Eli Lilly launches Mounjaro head-to-head trial against Novo Nordisk's Wegovy aliu Fri, 04/21/2023 - 22:35

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US FDA makes EUA changes to Pfizer-BioNTech and Moderna Covid-19 vaccines

Pharmaceutical Technology

The US Food and Drug Administration (FDA) has made changes to the emergency use authorisations (EUAs) of the Pfizer -BioNTech and Moderna bivalent mRNA Covid-19 vaccines. The latest amendment aims to simplify the vaccination schedule for most people. The changes mean that the current bivalent vaccines for the original and Omicron BA.4/BA.5 strains can now be utilised for all doses administered to those aged six months and above.

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More Trending

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Tech Is Changing Physical Therapy Treatment, but We Still Need a Human Touch

MedCity News

By combining in-home and virtual care, we can meet patients literally where they are. More importantly, we can improve outcomes, reduce costs and help patients get back to a normal life while giving therapists the flexibility and opportunity to provide more customized care for their patients.

Patients 137
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'The Top Line': How Pfizer became the first in Big Pharma history to break $100B in sales, plus this week's headlines

Fierce Pharma

'The Top Line': How Pfizer became the first in Big Pharma history to break $100B in sales, plus this week's headlines tcarey Thu, 04/20/2023 - 14:46

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The 99 seconds that changed this CEO’s life

PharmaVoice

Peter Kirk’s marathon story of inspiration and perseverance.

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SAB secures FDA breakthrough therapy status for influenza immunotherapy

Pharmaceutical Technology

SAB Biotherapeutics has received breakthrough therapy designation (BTD) from the US Food and Drug Administration (FDA) for SAB-176, an investigational immunotherapy to treat influenza. The newly granted status allows SAB to speed up the development and review of SAB-176, which is currently being studied for use in post-exposure prophylaxis for Type A and Type B influenza in high-risk patients, including those with anti-viral resistant strains.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Glen Tullman’s 5 Predictions for Healthcare’s Future

MedCity News

Glen Tullman — CEO of care navigation company Transcarent, as well as former CEO of Allscripts and Livongo — discussed what he thinks the future of healthcare will look like during the HIMSS conference in Chicago. He laid out five predictions, including an increased focus on consumer expectations and more investment in AI.

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In Pfizer's $43B acquisition of Seagen, the biotech's patience paid off

Fierce Pharma

In Pfizer's $43B acquisition of Seagen, the biotech's patience paid off kdunleavy Mon, 04/17/2023 - 11:34

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Merck to develop mAb through $10.8b acquisition

European Pharmaceutical Review

Merck & Co. Inc has agreed to acquire Prometheus Biosciences for $10.8 billion. The agreement is set to help advance PRA023, a novel humanised monoclonal antibody (mAb), developed by Prometheus. Its chosen indications are ulcerative colitis (UC) and Crohn’s disease (CD) and other autoimmune conditions. Prometheus is a clinical-stage biotechnology company.

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Twist Bioscience and Astellas team up for antibody discovery

Pharmaceutical Technology

Twist Bioscience and Astellas Pharma have entered a collaboration to help the latter to discover antibodies for immunotherapies. This is the third collaboration between the two companies. In May 2022, they signed a research partnership and exclusive option licence agreement for the development of antibodies to reduce tumour microenvironment-mediated immunosuppression.

Sales 105
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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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Why Is Health Tech Still Not Personalized?

MedCity News

Health technologies are often built based on the “reference man” and frequently don’t take other demographics into account. It shouldn’t be this way, experts argued on a panel Thursday at the HIMSS 2023 conference.

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Double whammy: Supreme Court slaps down separate bids from Novartis, Sanofi

Fierce Pharma

Double whammy: Supreme Court slaps down separate bids from Novartis, Sanofi esagonowsky Tue, 04/18/2023 - 08:25

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J&J Launches $50M Multiple Sclerosis Collaboration with Pipeline Therapeutics

PharmExec

J&J's Janssen Pharmaceutica NV collaborates with Pipeline Therapeutics in a $50 million licensing deal for oral MS drug PIPE-307, with potential earnings of up to $1 billion for Pipeline.

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Merck agrees to acquire Prometheus Biosciences for $10.8bn

Pharmaceutical Technology

Merck has signed a definitive agreement to buy clinical-stage biotechnology firm Prometheus Biosciences for $10.8bn, strengthening its immunology pipeline. The company will buy all of Prometheus Biosciences’ outstanding shares for $200 a share through a subsidiary. Prometheus Biosciences uses precision medicine to discover, develop and commercialise new therapeutic and companion diagnostic products to treat immune-mediated diseases.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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What is the Next Chapter for FDA’s Accelerated Approval’s in Oncology?

MedCity News

Over the past 2 years, concerted efforts have been undertaken by policymakers and FDA’s Oncology Center of Excellence to mitigate risks and improve the transparency of the accelerated approval program. These actions are crucial to restoring public trust – trust that has suffered considerable erosion.

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As Bayer's CEO switch nears, activist investor pushes harder for breakup, board changes

Fierce Pharma

As Bayer's CEO switch nears, activist investor pushes harder for breakup, board changes fkansteiner Fri, 04/21/2023 - 10:25

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Touchlight and 20Med partner on vaccine platform

PharmaTimes

Link-up has already delivered data showing the promise of nanoparticle-formulated doggybone DNA

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NICE recommends therapy duo for advanced leukaemia

European Pharmaceutical Review

Imbruvica ® (ibrutinib) plus venetoclax has been recommended as an option for untreated chronic lymphocytic leukaemia (CLL) in adults by the National Institute for Health and Care Excellence (NICE). Ibrutinib is a tyrosine kinase inhibitor (TKI) therapy. By blocking Bruton’s tyrosine kinase (BTK), which is needed by cancer cells to multiply and spread, ibrutinib could help stop them from growing and dividing.

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How to Prove Marketing Value: Demonstrate Content ROI and Contribution to Sales

Every marketer knows how important it is to prove their efforts drive sales opportunities, but that’s easier said than done. When problems like sales and marketing misalignment, lack of data, and wasted efforts persist, marketers can’t measure, prove, or increase their impact on revenue at a time when demonstrating marketing value is critical. Using analyst and expert data, this guide to marketing impact and content attribution explains: How B2B buyers use content The most common types of conten

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We Need to Work Across Sectors to Advance Health Equity, Global Health Leaders Say

MedCity News

Health disparities are often a result of other socioeconomic factors like housing and nutrition. Because of this, the healthcare industry needs to work with other sectors to improve health equity, said Hans Kluge, regional director for Europe of the World Health Organization, at the HIMSS 2023 conference.

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What spurred Lilly, Novo and Sanofi to slash insulin prices? Expert gives her take

Fierce Pharma

What spurred Lilly, Novo and Sanofi to slash insulin prices?

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FDA pushes Daiichi Sankyo’s quizartinib approval date by three months

Pharmaceutical Technology

The US Food and Drug Administration (FDA) has pushed quizartinib’s Prescription Drug User Fee Act (PDUFA) date in newly diagnosed FLT3-ITD positive acute myeloid leukemia (AML) for the review of updates of Risk Evaluation and Mitigation Strategies (REMS) included in the application. The PDUFA date was extended by three months to July 24, based on an April 20 company announcement.

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In London, Publishing Confronts AI

Copyright Clearance Center

The post In London, Publishing Confronts AI appeared first on Copyright Clearance Center.

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How to Stay Competitive in the Evolving State of Martech

Marketing technology is essential for B2B marketers to stay competitive in a rapidly changing digital landscape — and with 53% of marketers experiencing legacy technology issues and limitations, they’re researching innovations to expand and refine their technology stacks. To help practitioners keep up with the rapidly evolving martech landscape, this special report will discuss: How practitioners are integrating technologies and systems to encourage information-sharing between departments and pr

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What Are the Best Practices in Implementing AI in Healthcare?

MedCity News

With AI being so new, there are some best practices for companies to follow when bringing it into healthcare. This includes partnerships and understanding the shortcomings of AI, several experts said during a session at the HIMSS 2023 conference.

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Fierce Pharma Asia—Carvykti's massive myeloma win; BeiGene's PD-1 comeback

Fierce Pharma

Fierce Pharma Asia—Carvykti's massive myeloma win; BeiGene's PD-1 comeback aliu Thu, 04/20/2023 - 15:00

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Hasten Biopharmaceutic raises $315m for pipeline assets development

Pharmaceutical Technology

Chinese firm Hasten Biopharmaceutic has raised $315m for business development of its pipeline assets in a financing round co-led by Singapore-based CBC Group and Abu Dhabi sovereign wealth fund Mubadala Investment, The funding round was supported by additional institutional investors. Hasten will also use the proceeds from the round to fund future acquisitions.

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10 Questions to Ask When Searching for a Corporate Literature Management Solution

Copyright Clearance Center

The post 10 Questions to Ask When Searching for a Corporate Literature Management Solution appeared first on Copyright Clearance Center.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time