Mon.Apr 15, 2024

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Pfizer, BioNTech win pause in patent infringement case from rival Moderna

Fierce Pharma

After nearly two years of legal back and forth, Pfizer and its German partner BioNTech have won a brief reprieve in their patent fight against mRNA rival Moderna. | In a docket entry dated Friday, Massachusetts federal judge Richard G. Stearns granted a stay on Moderna's COVID-19 vaccine patent infringement lawsuit against Pfizer and BioNTech. The move will give the Patent Trial and Appeal Board more time to review challenges against two of the three relevant patents in the litigation.

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Traditional gene therapies are uber-niche. Ocugen hopes to change that.

PharmaVoice

The biotech is developing a ‘gene-agnostic’ approach to expand the patient pool for gene therapies.

Patients 145
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Novartis touts surrogate endpoint win, nabs priority review for Fabhalta in IgAN

Fierce Pharma

A Novartis drug with "pipeline in a pill" potential, according to one analyst group, has delivered on that promise once again. | In a phase 3 trial, treatment with Fabhalta led to a statistically significant 38.3% reduction of proteinuria (protein in the urine) in patients with IgA nephropathy, Novartis said on Monday.

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Two CVS Locations Make Moves To Join National Pharmacy Union Movement

MedCity News

Two CVS stores in Rhode Island have filed petitions to join the Pharmacy Guild, which is building a national pharmacy union. The locations are close to CVS Health’s headquarters in Woonsocket, Rhode Island. The post Two CVS Locations Make Moves To Join National Pharmacy Union Movement appeared first on MedCity News.

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AI Strategies for Sales Managers: How to Cut Down on Tedious Admin Work

What if you could help your sellers stop wasting 72% of their day on non-selling activities and focus on bringing in revenue? Incorporating AI in your enablement workflows can help you cut down on busy work, get projects done faster, and let your team (and you!) focus on making a bigger impact. We put together this guide to show you how to use AI to cut time and costs for projects, including collateral creation, development of training videos, and automating tedious processes.

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Boehringer Ingelheim leans on late-stage pipeline, plots 25 new launches over the next decade

Fierce Pharma

Boehringer Ingelheim’s 2023 was largely marked by the highly anticipated launch of its Cyltezo, the first interchangeable biosimilar to AbbVie’s Humira. | The company's late-stage pipeline focuses on oncology, cardiorespiratory diseases, mental health and cardiovascular-renal-metabolic conditions. Boehringer looks to kick off ten new phase 2 and 3 trials in the next 12-18 months, it said in its earnings release.

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Preclinical Safety Signal Prompts FDA Clinical Hold on Neumora Schizophrenia Drug

MedCity News

The FDA clinical hold keeps Neumora Therapeutics from catching up to the field of biopharmaceutical companies pursuing the same target for schizophrenia. But Neumora remains on track with its lead program, a different drug in late-stage clinical testing for major depressive disorder. The post Preclinical Safety Signal Prompts FDA Clinical Hold on Neumora Schizophrenia Drug appeared first on MedCity News.

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Regeneron launches $500m venture capital arm

pharmaphorum

Regeneron has formed a corporate venture capital unit with $100 million a year to invest over the next five years in “biopharmaceutical, healthcare, and health technology” start-ups.

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Marinus faces share-price collapse, weighs 'cost-saving strategies' after IV seizure med comes up short

Fierce Pharma

Marinus Pharmaceuticals’ attempt to expand the use of its seizure medicine in a new formulation has hit a pothole. | Marinus Pharmaceuticals’ attempt to expand the use of its seizure medicine in a new formulation has hit a pothole. As a result, the company is “evaluating potential cost-saving strategies,” CEO Scott Braunstein, M.D., said in a release.

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Francis Crick researchers reveal pathways linking intestinal inflammation and colitis

PharmaTimes

Affecting over 500,000 people in the UK, IBD comprises Crohn’s disease and ulcerative colitis

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Roche eyes earlier treatment nod after Columvi-chemo trial win in 2nd-line lymphoma

Fierce Pharma

As Genentech bolsters its hematology portfolio with new antibody drugs and bispecifics, the Roche unit has revealed a trial win that could push its recently approved T-cell engager Columvi int | The study paired Columvi, a CD20xCD3 bispecific T-cell engager, with the chemotherapy GemOx (glofitamab-gxbm) in patients who’d tried at least one prior line of therapy and did not qualify for autologous stem cell transplants.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Why Banner Health Is Scaling Automation Tech In Its Operating Rooms

MedCity News

Banner Health is deploying Qventus’ perioperative technology across the entire organization following the success of an initial pilot. The software integrates with EHRs and uses machine learning to automate operating room scheduling processes and maximize surgical caseloads. The post Why Banner Health Is Scaling Automation Tech In Its Operating Rooms appeared first on MedCity News.

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Activist hedge fund seeks big shake-up at Novavax

pharmaphorum

Shah Capital has fired a broadside at the management team of Novavax, seeking a change in leadership at the vaccine company and the appointment of two handpicked directors to the board. In an open letter, the hedge fund accuses Novavax’s leadership of squandering its “many significant competitive advantages and sizeable market opportunity” due to “self-inflicted problems” under the current team led by chief executive John Jacobs.

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How Technology Can Alleviate Dental Workforce Challenges

MedCity News

Current technology can’t single-handedly solve all dental workforce issues, but there is much it can do to lighten the burden. The post How Technology Can Alleviate Dental Workforce Challenges appeared first on MedCity News.

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After ph3 win, Roche eyes earlier use of Columvi in DLBCL

pharmaphorum

Roche’s CD20xCD3 bispecific antibody Columvi has improved survival when used as a second-line therapy for diffuse large B-cell lymphoma (DLBCL) in a phase 3 trial, setting up regulatory filings for earlier use of the drug in the treatment pathway.

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How to Prove Marketing Value: Demonstrate Content ROI and Contribution to Sales

Every marketer knows how important it is to prove their efforts drive sales opportunities, but that’s easier said than done. When problems like sales and marketing misalignment, lack of data, and wasted efforts persist, marketers can’t measure, prove, or increase their impact on revenue at a time when demonstrating marketing value is critical. Using analyst and expert data, this guide to marketing impact and content attribution explains: How B2B buyers use content The most common types of conten

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The New Authenticity: SXSW 2024 Insights, Part 2

Eversana Intouch

At SXSW 2024, amidst a confluence of marketing, technology, AI, and design, one word seemed to echo through every conversation, panel, and workshop: authenticity. It’s fascinating, isn’t it? The idea of being genuine, real, and true — qualities so deeply sought after in everything we do, yet so complex and rich when we pause to unpack them. Among the minds at EVERSANA INTOUCH, with leaders spanning the spectrum from Strategic Planning to Creative Direction, and from Experience Design to Customer

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Healthware re-launches as Eversana Intouch full service affiliate

pharmaphorum

Life sciences service provider (and pharmaphorum parent company) Eversana has completed the integration of Healthware Group, the Italy-based global agency and consultancy it acquired in October. The group will now be known as Eversana Intouch Healthware and will operate as Eversana’s sixth full-service affiliate.

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Trial Findings for Minimally Invasive Parafascicular Technology Show Promise for Intracerebral Hemorrhage Treatment

Pharmaceutical Commerce

Results of the trial suggest that early intervention for intracerebral hemorrhage using parafascicular surgery were safe.

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Study warns of chronic kidney disease timebomb

pharmaphorum

Up to one in six people in eight industrialised nations could be suffering from chronic kidney disease (CKD) by 2032, with dire consequences for “patients, [the] planet, and economies,” says a new study.

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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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Pharma Pulse 4/15/24: Increase in ransomware attacks to healthcare's remote access systems, The Health and Healthcare of Gen Xers & more

Pharmaceutical Commerce

The latest news for pharma industry insiders.

Pharma 105
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Nine UCL researchers secure £560m in research funding from ERC

PharmaTimes

Approximately 14% of the competition-submitted proposals were selected to receive funding

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Long-term data indicates “significant” potential of aGvHD microbiome treatment

European Pharmaceutical Review

Positive data from MaaT Pharma’s Microbiome Ecosystem Therapy TM (MET) MaaT013 as a treatment for acute graft-versus-host disease (aGvHD), is set to be presented at the 2024 European Society for Blood and Marrow Transplantation (EBMT) Annual Meeting. Based on the long-term survival data, at 18 months MaaT013 enabled 42 percent overall survival in all patients and 58 percent in responder patients.

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FDA Establishes Center for Clinical Trial Innovation

PharmaTech

C3TI will promote CDER’s clinical trial innovation activities both internally and externally.

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Increase Revenue With Better, Faster Sales Onboarding

Quotas need to be hit. Revenue goals need to be met. This reality makes shortening sales onboarding time a top priority. Organizations with a standard onboarding process boost employee retention by 58% and increase productivity by 50%. Unfortunately, many companies struggle with inefficient processes that lead to high turnover and missed revenue opportunities.

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Fujifilm plans $1.2 billion investment in major US manufacturing facility

European Pharmaceutical Review

FUJIFILM Corporation is planning to invest $1.2 billion to expand the planned FUJIFILM Diosynth Biotechnologies manufacturing facility in Holly Springs, North Carolina, US. This news follows the organisation’s announcement of a $2 billion investment in the facility in March 2021. This additional financial boost totals the investment to over $3.2 billion, FUJIFILM confirmed.

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From skepticism to strategy: How AI is transforming the IP practice

Clarivate

Artificial intelligence (AI) is evolving rapidly with new business use cases constantly emerging. So, how do law firms and in-house counsels ensure they don’t get left behind? Our research found that IP professionals are currently grappling with what AI could mean for them, their practice and their processes. They are keen to realize benefits but are largely skeptical about AI deployment with relatively low industry adoption.

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Seasonal variation of microbial contamination in pharmaceutical cleanrooms

European Pharmaceutical Review

Researchers investigating environmental microbial contamination found “no seasonal climatic influences were observed” in bacteria and fungi counts present in Grade D (ISO 8) Brazilian pharmaceutical cleanrooms. Samples were obtained via surface and air monitoring over a one-year period. While microbial levels were predicted to be higher during rainy periods compared to dry spells, “no statistically significant differences in bacteria and fungi counts were found between months or seasonal period

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ImmunityBio gets grant for cross-reactive SARS-COV2 vaccine composition for multiple coronaviruses

Pharmaceutical Technology

Discover ImmunityBio Inc's groundbreaking patent for a cross-reactive SARS-CoV2 vaccine targeting multiple variants. Learn how this innovative method boosts immune response and memory cells for enhanced protection.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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ebook: Twin-screw extrusion for pharmaceutical applications

European Pharmaceutical Review

Hot-melt extrusion can help overcome many pharmaceutical formulation challenges since it is a straightforward technique to compound all excipients on a molecular level. Various dosage forms can be produced with a twin-screw extruder and corresponding downstream equipment. These include solid oral dosage forms such as buccal and transdermal, as well as new delivery systems like subcutaneous implants and transmucosal applications.

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Empowering Oncology Pharmacists: Driving Innovation and Advancement Through Pharmacist-Led Research

Pharmacy Times

The impact pharmacist-led research on oncology pharmacy practice in the field of oncology is undeniable.

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Evaluating the Partnership between mRNA and LNPs

PharmaTech

The LNP success in mRNA vaccines leads to their establishment as a standard in mRNA delivery.

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The cutting-edge monitoring technology that is transforming the future of clinical trials

Pharmaceutical Technology

Pharmaceutical innovations require an extra layer of precision and care in the supply chain process.

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Using Generative AI in Sales: Pros, Cons, and Considerations According to Sellers

Are your sellers unsure about using AI in their day-to-day workflows? Or are they eager to try but uncertain where to start? They might be asking: Which tasks are best suited for AI? How will using AI affect my relationship with my customers? With so many tools available, which ones are the most useful to me? To help answer these and other common questions about using AI during the sales cycle, we surveyed B2B sellers who were early adopters to get their insight and advice about how to use gen A