Tue.Jul 30, 2024

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Pfizer tacks on $1B to 2024 revenue outlook amid cost-cutting drive

Fierce Pharma

For more than a year after Pfizer’s COVID product sales peaked at the end of 2022, the company’s quarterly revenues showed year-over-year declines. | For the first time since its sales peaked during the pandemic, Pfizer registered year-over-year revenue growth during the second quarter of 2024. And while the busy has been busy trimming operating expenses, it did add $1 billion to its total revenue projection for the year.

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Analysis: Humana is Boldly Going Where Walmart Stumbled

MedCity News

Humana is leasing clinical space at 23 Walmart Supercenter retail stores. The move is logical for the insurer as it builds out its senior primary care business, experts say. The post Analysis: Humana is Boldly Going Where Walmart Stumbled appeared first on MedCity News.

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Sanofi sues Sarepta, claiming Duchenne gene therapy Elevidys infringes 2 manufacturing patents

Fierce Pharma

Six months after surviving a patent challenge involving its $3.2 million gene therapy, Sarepta faces a new lawsuit from another gene therapy developer claiming the approved treatment infringes its | Six months after surviving a patent challenge involving its $3.2 million gene therapy, Sarepta faces a new lawsuit from another gene therapy developer claiming the approved treatment infringes active patents.

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Eco HPLC-based method shows promise for Z-alkene synthesis

European Pharmaceutical Review

Japanese researchers have developed a new method for photoisomerisation of E -cinnamamides to Z -cinnamamides. The approach uses a recycling photoreactor coupled with a high-performance liquid chromatography (HPLC) system. As organic compounds, many Z -alkenes “cannot be prepared through conventional methods involving thermodynamic methods”. On the other hand, “photoisomerisation can offer good yields”, they noted.

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Increase Revenue With Better, Faster Sales Onboarding

Quotas need to be hit. Revenue goals need to be met. This reality makes shortening sales onboarding time a top priority. Organizations with a standard onboarding process boost employee retention by 58% and increase productivity by 50%. Unfortunately, many companies struggle with inefficient processes that lead to high turnover and missed revenue opportunities.

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Incyte touts 2 trial wins for PD-1 drug Zynyz, eyes comeback in anal cancer

Fierce Pharma

Incyte is gunning for a first-in-class nod for PD-1 inhibitor Zynyz in anal cancer again after being turned away by the FDA in 2021. | Incyte is gunning for a first-in-class nod for its PD-1 inhibitor Zynyz in anal cancer again after being turned away by the FDA in 2021. But regulatory uncertainties remain.

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Spinal Surgery in The Setting of Complex Medical Conditions

MedCity News

Empathy gets rationed when a high-volume practice is valued over a high-quality practice by administrators who aren’t seeing the patients in clinic — but patients rely on surgeons who can embrace the complex conditions. The post Spinal Surgery in The Setting of Complex Medical Conditions appeared first on MedCity News.

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More Trending

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The Science of Stories: Leveraging Storytelling to Enhance Sales

Quantified

The Power of Storytelling in Sales When was the last time you got lost in a story? Whether in a book, podcast, or movie, a well-told story has a powerful impact on its audience. When messages delivered as stories can be up to 22 times more memorable than mere facts. Stories engage multiple parts of our brains, enhancing focus and retention. Your Brain on Stories Neurological Engagement: Stories activate multiple brain areas, including motor cortexes, emotion, and visual processing centers, makin

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MedCity Moves Podcast: Recent Hires, Layoffs & an Interview with Aneesh Chopra, Chief Strategy Officer at Arcadia

MedCity News

In this month’s episode, Senior Reporter Katie Adams discussed some executive moves and layoffs that recently occurred in the healthcare sector. She also interviewed Aneesh Chopra, who transitioned to the role chief strategy officer at Arcadia following the company’s recent merger with his startup, CareJourney. The post MedCity Moves Podcast: Recent Hires, Layoffs & an Interview with Aneesh Chopra, Chief Strategy Officer at Arcadia appeared first on MedCity News.

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Approaching the regulatory world with passion: CERs and EU MDR processes

pharmaphorum

In a new pharmaphorum podcast, web editor Nicole Raleigh speaks with Ethan Drower, co-founder and CEO of Cite Medical Solutions, a company providing full Clinical Evaluation Report (CER) services and industry literature review for European Union Medical Device Regulation (or EU MDR) processes.

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Why One Physical Therapy Provider Thinks Hybrid Care is Key

MedCity News

Band Connect’s founders believe their startup’s unique hybrid physical therapy model is helpful in boosting both compliance and outcomes. The post Why One Physical Therapy Provider Thinks Hybrid Care is Key appeared first on MedCity News.

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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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GSK and Flagship Pioneering link for new medicines and vaccines

Pharmaceutical Technology

GSK has announced a strategic collaboration with Flagship Pioneering for the discovery and development of medicines and vaccines.

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Thwarting The Next Surge: A Tactical Plan to Improve Covid-19 Vaccination Uptake

MedCity News

In the face of new variants and lower public acceptance of vaccination, it’s imperative that we take stock of lessons learned from previous seasons and examine key barriers to uptake as we prepare for this fall and winter – from adjusting approval timelines at the federal level, to implementing programs to address vaccine complacency, convenience and confidence.

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Study finds semaglutide decreases tobacco-related healthcare

Pharmaceutical Technology

Semaglutide, marketed as Ozempic and Wegovy, decreased tobacco-related healthcare encounters compared to other medications.

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With FDA Nod for Colorectal Cancer Screening, How Much Market Share Can Guardant’s Blood Test Get?

MedCity News

Guardant Health’s Shield, a liquid biopsy that screens for colorectal cancer by analyzing a patient blood sample, will compete against stool-based tests already established in the market. Shield could also face new competition from other liquid biopsy companies. The post With FDA Nod for Colorectal Cancer Screening, How Much Market Share Can Guardant’s Blood Test Get?

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Using Generative AI in Sales: Pros, Cons, and Considerations According to Sellers

Are your sellers unsure about using AI in their day-to-day workflows? Or are they eager to try but uncertain where to start? They might be asking: Which tasks are best suited for AI? How will using AI affect my relationship with my customers? With so many tools available, which ones are the most useful to me? To help answer these and other common questions about using AI during the sales cycle, we surveyed B2B sellers who were early adopters to get their insight and advice about how to use gen A

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BioNTech cancer vaccine hits the spot in melanoma

pharmaphorum

mRNA specialist BioNTech has chalked up an important win in its cancer pipeline, showing efficacy with its BNT111 vaccine candidate in a phase 2 trial in advanced melanoma.The study is looking at the combination of BNT111 with Regeneron's PD-1 inhibitor Libtayo (cemiplimab) in 184 patients with advanced melanoma who have relapsed after or not responded to treatment with a PD-1/PD-L1 inhibitor, or the two therapies given alone.

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Pharma Pulse 7/30/24: The Doctor Will See You Now, But AI May Be Listening In.The Importance of Genomic Sequencing in the Battle Against HIV in South Africa & more

Pharmaceutical Commerce

The latest news for pharma industry insiders.

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Older GLP-1 drug shows glimmer of benefit in Alzheimer's

pharmaphorum

A small study of Novo Nordisk's once-daily injectable GLP-1 agonist liraglutide shows a benefit in patients with Alzheimer's disease

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HDR UK and DPUK granted £2m for new motor neurone disease research initiative

PharmaTimes

The rapidly progressive neurological condition affects around 5,000 people in the UK

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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Cognition's SHINE data for Alzheimer's drug dulls prospects

pharmaphorum

Cognition Therapeutics has reported phase 2 data with its Alzheimer's disease candidate, claiming the results show proof-of-concept for the drug, although the study missed its main endpoint.Cognition's stock lost more than 40% of its value in trading after the data was presented yesterday, and slipped another 20% after hours, despite assertions by the New York biotech that its CT182 drug showed "consistent" improvements in cognitive outcomes compared to placebo in the SHINE study.

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FDA Approves Luye Pharma Group’s Erzofri for Adults with Schizophrenia, Schizoaffective Disorder

PharmExec

Erzofri is the first patented paliperidone palmitate long-acting injectable developed in China to receive FDA approval for treating schizophrenia and schizoaffective disorder, company says.

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10 Ways to Improve Video Calls with Prospects

Quantified

Selling in a virtual world is challenging. For reps who thrive in person, gone are the days of meeting prospects at conferences, dinners, and golf outings. Now, high-value solutions are sold over video calls. Even for reps accustomed to virtual sales, the very real phenomenon of Zoom fatigue means the competition for the buyer’s attention is higher than ever as tech-tired prospects juggle browser tabs, Slack notifications, and their newly merged home and work lives.

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FDA Grants Priority Review to Novartis’ Scemblix for Newly Diagnosed Patients with Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase

PharmExec

Results from the ASC4FIRST study lead to FDA priority review designation of Scemblix in newly diagnosed patients with Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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It’s Time for My Summer Break

Cesare Ferrari

As the summer season approaches, it’s time for my usual break. For a few weeks, I will pause my postings and plan to return to my regular schedule of bi-weekly updates in September. Before I go, I’d like to share a summary of some series I’ve published over the years: Cultural Factors in International Medical Sales Selling medical products (devices or drugs) internationally involves understanding and managing cultural differences.

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The Broader Societal Implications of Maternal Health Issues

PharmExec

In this part of her Pharmaceutical Executive video interview, Charlotte Owens, MD, FACOG, Head of Medical Affairs and Outcomes Research at Organon, discusses the societal implications of maternal health issues both short and long term.

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7 years after launch, Sanofi’s Dupixent is set for a megablockbuster run

PharmaVoice

Dupixent hasn’t generated as much buzz as top-sellers like Keytruda or Ozempic, but the drug is boosting Sanofi’s earnings into the future.

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Study reveals new insights into ‘gene misbehaviour’ in healthy populations

PharmaTimes

The findings could support investigations into human genetics and various complex diseases

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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Ventyx scraps TYK2 inhibitor after Phase II Crohn’s defeat 

Pharmaceutical Technology

Ventyx no longer plans to conduct additional clinical trials of VTX958 with internal resources after the Phase II trial missed its primary endpoint.

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AvaSure Acquires Ouva and Adds Smart Room Solutions to its Platform

PharmExec

OncLive serves as the connection to oncology, including groundbreaking cancer news and interviews with top oncologists in multimedia formats.

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First Approved Stelara Biosimilar Launched in Europe by STADA and Alvotech

PharmaTech

STADA and Alvotech have launched Uzpruvo in Europe, making it the first approved biosimilar to Stelara (ustekinumab) in the European market.

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NRx Receives Response From FDA Over Testing Use of Ketamine for Suicidal Depression in Adolescents

PharmExec

OncLive serves as the connection to oncology, including groundbreaking cancer news and interviews with top oncologists in multimedia formats.

FDA 52
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.