Tue.Dec 05, 2023

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As Stelara cliff looms, J&J expects 25 blockbuster drugs to drive future sales growth

Fierce Pharma

As Johnson & Johnson places a magnifying glass on its pharmaceutical business, the focus for the remainder of the decade rests on the shoulders of some 25 new and upcoming drugs.

Sales 312
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Moving Beyond Medicine To Treat Chronic Pain

MedCity News

I look at non-pharmacological approaches like digital therapeutics as having the potential to give someone like me living with chronic pain everything I need to make a healthy recovery: access to digital treatments and clinicians, to community, coaching, and navigation services.

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Travere cuts workforce by 20% as Filspari's prospects are up in one rare kidney disease, down in another

Fierce Pharma

Travere Therapeutics will reduce its workforce by 20%, with the jo | Travere Therapeutics will reduce its workforce by 20%, with the job cuts focused on “non-field-based employees,” the company said on Tuesday. The layoffs are part of a shake-up of the San Diego-based company as it focuses on its launch of kidney drug Filspari and develops pegtibatinase as a potential treatment for the metabolic disorder homocystinuria (HCU).

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Expert: The Killer App of AI in Radiology Is Anything that Boosts Workflow Integration

MedCity News

The AI tools that radiologists need the most are ones that integrate their workflows and make it easier to access past images, said Dr. Jocelyn Chertoff, radiology chair at Dartmouth Health. When adopting AI to address their workforce shortage, hospitals need to involve clinicians early-on in decisions about what new tools to implement, she also noted.

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AI Strategies for Sales Managers: How to Cut Down on Tedious Admin Work

What if you could help your sellers stop wasting 72% of their day on non-selling activities and focus on bringing in revenue? Incorporating AI in your enablement workflows can help you cut down on busy work, get projects done faster, and let your team (and you!) focus on making a bigger impact. We put together this guide to show you how to use AI to cut time and costs for projects, including collateral creation, development of training videos, and automating tedious processes.

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SABCS: Seagen outlines Tukysa's value alongside Roche's ADC in breast cancer. But FDA path remains unclear

Fierce Pharma

As antibody-drug conjugates (ADCs) grow their importance in the oncology treatment space, efforts are underway to combine them with other agents. Enter Seagen. | Seagen unveiled detailed data showing its Tukysa could offer additional tumor progression benefit on top of Roche’s ADC Kadcyla. But with a negative early trend in overall survival, Seagen seems not ready to knock on the FDA’s door.

FDA 259
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After Data Miss in Lead Cancer Indication, Replimune Maps Path for Oncolytic Virus

MedCity News

Replimune’s lead therapeutic candidate did not meet the two main goals of a study intended to support an FDA submission in cutaneous squamous cell carcinoma. But Replimune’s therapy, an oncolytic virus, has better data in melanoma, and the company plans a 2024 FDA submission in this skin cancer.

Leads 119

More Trending

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Hims & Hers Gets Into Weight Loss Treatment

MedCity News

Hims & Hers unveiled a new weight loss program on Monday that includes access to medications, educational content and digital tracking tools.

Education 119
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Pharma group blasts UK's drug rebate scheme shortly after lauding 'landmark' spending deal

Fierce Pharma

Despite what was presented as a “landmark” deal between the pharmaceutical companies and the government, the U.K.’s pharma association has not stopped pressuring the government for more industry-fr | Despite what was presented as a “landmark” deal between the pharmaceutical companies and the government, the U.K.’s pharma association has not stopped pressuring the government for more industry-friendly spending policies.

Pharma 147
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How the Patient Perspective Can Drive Powerful Clinical Study Designs in Oncology

MedCity News

Regulators and experts consider patient-reported outcomes (PROs) as the gold standard when assessing a patient’s subjective treatment experience. As such, ePROs can be the key to product differentiation for sponsors seeking to highlight their product’s ease of administration, tolerability, or compatibility in combination with other components of a treatment regimen.

Patients 119
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FDA Grants Breakthrough Designation to Johnson & Johnson’s Novel Treatment for HR-NMIBC

PharmExec

TAR-200 has a novel targeted releasing system for the treatment of patients with Bacillus Calmette-Guérin-unresponsive high-risk non-muscle-invasive bladder cancer who are ineligible for bladder removal surgery.

FDA 116
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Amicus Leader, BIO Board Member John Crowley Named Trade Group’s New CEO

MedCity News

BIO’s new president and CEO is a familiar face. John Crowley, a longtime BIO board member, was named the life sciences industry trade group’s new leader, starting in March.

Biopharma 118
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Phase III data for novel telomerase inhibitor released

European Pharmaceutical Review

Results from Geron’s Phase III IMerge trial evaluating its first-in-class investigational telomerase inhibitor imetelstat, have shown long-term and durable response in participants with a rare haematologic malignancy. Efficacy of the treatment was compared to placebo in patients with lower risk myelodysplastic syndromes (MDS) relapsed/refractory or ineligible for erythropoiesis stimulating agents (ESAs).

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Ketryx Rakes In $14M to Speed Up Medical Device Development & Quality Assurance

MedCity News

Ketryx raised $14 million in Series A funds. The startups sells a platform — designed around FDA regulations and quality standards — that automates much of the work required from medical device companies’ development and quality teams.

Medical 116
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Q&A: Tackling the rise of fake anti-obesity drugs on the market

Pharmaceutical Technology

Professor Timothy Mackey talks about the recent reports of fraudulent Ozempic pens and the challenges in chasing drug counterfeiters.

Marketing 111
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How to Prove Marketing Value: Demonstrate Content ROI and Contribution to Sales

Every marketer knows how important it is to prove their efforts drive sales opportunities, but that’s easier said than done. When problems like sales and marketing misalignment, lack of data, and wasted efforts persist, marketers can’t measure, prove, or increase their impact on revenue at a time when demonstrating marketing value is critical. Using analyst and expert data, this guide to marketing impact and content attribution explains: How B2B buyers use content The most common types of conten

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BMS chases MSD/Seagen with first-line bladder cancer filing

pharmaphorum

BMS chases MSD/Seagen with first-line bladder cancer filing Phil.

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Roche to advance novel obesity and diabetes treatments

European Pharmaceutical Review

Roche has agreed to acquire biotech Carmot Therapeutics for an upfront purchase price of $2.7 billion, enabling the Swiss pharma company to add a range of incretin treatments for obesity and diabetes to its portfolio. Incretins are “gut hormones that are secreted after food intake and play a role in modulating blood glucose by stimulating insulin secretion and suppressing appetite,” Roche highlighted.

Food 110
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Roche bounces back in PIK3 with inavolisib data

pharmaphorum

Roche bounces back in PIK3 with inavolisib data Phil.

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KCL molecular communication system to revolutionise drug delivery

PharmaTimes

The platform safely and effectively replicates the electric signalling process compounds - News - PharmaTimes

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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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UK’s entrance into Horizon Europe finalised

European Pharmaceutical Review

With the UK set to become an associated country to Horizon Europe on 1 January 2024, the political agreement on UK’s association to Horizon Europe has been adopted. Now, this final step in the process has been implemented by the EU-UK Specialised Committee on Participation in Union Programmes (SCPUP), the European Commission (EC) has announced. The programme is the EU’s key funding initiative for research and innovation with a budget of €95.5 billion for 2021-27.

Education 105
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Pharma accuses UK of ‘mixed messages’ on rebate schemes

pharmaphorum

The pharma industry and the UK government may have reached an accord on the voluntary scheme of rebates used to limit rises in medicines spending in the UK, but the alternative statutory scheme remains a prickly subject.

Pharma 105
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NIHR invests £55m to tackle health inequalities and outcomes

PharmaTimes

Millions of people in the UK are set to benefit from the second wave of funding - News - PharmaTimes

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Alto hits a high note with AI-driven depression therapy

pharmaphorum

Alto hits a high note with AI-driven depression therapy Phil.

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Increase Revenue With Better, Faster Sales Onboarding

Quotas need to be hit. Revenue goals need to be met. This reality makes shortening sales onboarding time a top priority. Organizations with a standard onboarding process boost employee retention by 58% and increase productivity by 50%. Unfortunately, many companies struggle with inefficient processes that lead to high turnover and missed revenue opportunities.

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Drug Solutions Podcast: Staying on Track with Formulation of Cell Culture Media

PharmaTech

Tom Fletcher, director of Research and Development at FUJIFILM Irvine Scientific; and Bob Newman, PhD, chief scientific director at FUJIFILM Irvine Scientific, discuss formulation, specifically with how to prepare culture media for use, single use technologies, and automations to create closed systems in cell/gene therapies with former Pharmaceutical Technology editor Jill Murphy.

Media 98
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Oxford Biomedica agrees to acquire ABL Europe

Pharmaceutical Technology

Oxford Biomedica has signed an agreement to acquire CDMO ABL Europe from Institut Mérieux subsidiary TSGH SAS in a deal worth €15m ($16.27m).

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Eli Lilly Announces Availability of Obesity Drug Zepbound at US Pharmacies

PharmExec

Patients with obesity are now able to access Zepbound (tirzepatide) with a prescription at retail and mail-order pharmacies across six dose strengths.

Retail 64
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A Day In The Life Of A Cardiac Rhythm Clinical Specialist With Crystal Sobande

Evolve Your Success

Being present is not just a strategy; it’s the heartbeat of professional evolution. In this episode, Crystal Sobande , Cardiac Rhythm Clinical Specialist, openly discusses her transition from selling cosmetic dermatology treatments to navigating the ever-changing world of medical devices. Discover the behind-the-scenes hustle and unpredictability as Crystal walks us through the typical day in her life.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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FDA accepts Vanda Pharmaceuticals’ NDA for gastroparesis treatment

Pharmaceutical Technology

The US FDA has accepted the NDA filed by Vanda Pharmaceuticals for its drug tradipitant to treat gastroparesis symptoms.

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New Risk Factor Found for Future Cardiovascular Disease in Patients With Systemic Lupus Erythematosus

Pharmacy Times

Investigators found that positive antiphospholipid antibodies and traditional risk factors were associated with atherosclerotic cardiovascular disease.

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Changes to hospital price transparency requirements address data availability and quality

Clarify Health

Since January 2021, U.S. hospitals must share clear, accessible information online about the standard charges for the services provided to improve healthcare price transparency. Unfortunately, however, compliance with CMS regulations has been lacking. As of last summer, and more than two and a half years after the enforcement date, only about a third of hospitals fully complied with hospital price transparency requirements.

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Long-term Chia Seed Supplementation May Significantly Lower Systolic Blood Pressure

Pharmacy Times

Chia seeds are a nutrient dense product that are rich in fiber and omega-3 fatty acids, and could have a hypocholesterolemic effect when ingested.

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Using Generative AI in Sales: Pros, Cons, and Considerations According to Sellers

Are your sellers unsure about using AI in their day-to-day workflows? Or are they eager to try but uncertain where to start? They might be asking: Which tasks are best suited for AI? How will using AI affect my relationship with my customers? With so many tools available, which ones are the most useful to me? To help answer these and other common questions about using AI during the sales cycle, we surveyed B2B sellers who were early adopters to get their insight and advice about how to use gen A