Tue.Jan 02, 2024

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Millions of doses of Pfizer's Paxlovid will go to waste in UK, EU as COVID demand plummets

Fierce Pharma

On the heels of a major Paxlovid inventory write-off in the United States, many more doses of Pfizer's COVID-fighting antiviral are going to waste overseas. | At the end of November, more than 1.5 million courses of Pfizer’s Paxlovid had expired unused in European countries, analysts at Airfinity said in a new report. The total tally of expired doses in Europe is expected to hit 3.1 million by the end of next month, representing a value of $2.2 billion.

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Report: Improving Health Equity is a Top-10 Goal for Most Healthcare Execs in 2024

MedCity News

A recent Deloitte report found that improving health equity is a top-10 goal for 83% of life sciences and healthcare C-suite executives in 2024. The report also laid out factors that will likely influence health equity in 2024, including AI.

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Inside AbbVie's $10B buyout of ImmunoGen—and the bidding war it swooped in on

Fierce Pharma

AbbVie is entering 2024 with a foothold in the antibody-drug conjugate (ADC) field thanks to its late-2023 buyout of ImmunoGen worth more than $10 billion. | According to a recent securities filing, AbbVie only entered the ImmunoGen bidding war after other buyout interest led the ADC specialist to widen its pool of potential purchasers. When it came down to the final three players, AbbVie's offer blew the others out of the water.

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Longboard Pharma Trial Data Show How It Could Stand Out in the Epilepsy Field

MedCity News

Longboard Pharmaceuticals’ epilepsy drug candidate bexicaserin met the main efficacy goal of its Phase 1b/2a study along with safety data suggesting a potential edge over current treatments. With Longboard now preparing to advance to Phase 3 testing, its stock price soared more than 300%.

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AI Strategies for Sales Managers: How to Cut Down on Tedious Admin Work

What if you could help your sellers stop wasting 72% of their day on non-selling activities and focus on bringing in revenue? Incorporating AI in your enablement workflows can help you cut down on busy work, get projects done faster, and let your team (and you!) focus on making a bigger impact. We put together this guide to show you how to use AI to cut time and costs for projects, including collateral creation, development of training videos, and automating tedious processes.

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AstraZeneca, Sanofi win nod in China for RSV antibody Beyfortus

Fierce Pharma

AstraZeneca and Sanofi have scored first in | AstraZeneca and Sanofi have scored first in China with an approval for their respiratory syncytial virus (RSV) immunization Beyfortus for infants, with the companies expecting the shot to be available there for the 2024-25 season. Beyfortus is the only immunization approved for babies entering their first RSV season to protect them against lower respiratory tract infection.

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STOP SETTLING: How Playing it Safe is Killing Your Medical Rep Career in 2024

Medical Sales Guru

The role of a medical sales representative involves navigating intricate dynamics with healthcare professionals. These professionals hold significant authority in determining a salesperson’s access and the fate of a product. Consequently, many representatives opt to play it safe , fearing potential alienation that might hinder future sales opportunities.

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Verona cuts $400m loan deal as it preps COPD drug for market

pharmaphorum

Verona Pharma has agreed a new $400 million debt facility with Oxford Finance and Hercules Capital designed to help the company navigate the possible approval and launch of ensifentrine, its therapy for chronic obstructive pulmonary disease (COPD). The Anglo-US company has already tapped $50 million of the funding and can take another $100 million if an ongoing review of ensifentrine by the US FDA results in regulatory approval.

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Are Rare Brain Diseases the Next Commercial Frontier for Gene Therapy?

MedCity News

The biggest trend in gene therapy development is the potential of several treatments for rare neurological diseases to move from the bench to the bedside.

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Novo Nordisk will open AI hub in London

pharmaphorum

Novo Nordisk is planning to open an AI research facility in London, UK, as part of a drive to place the technology at the heart of its drug discovery operations

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Private Equity Ownership Leads to Worse Patient Outcomes at Hospitals, Study Shows

MedCity News

Yet another study has been published showing that patients receiving care at PE-owned hospitals experienced a higher rate of hospital-acquired adverse events, like infections and falls, than patients receiving care at hospitals that are not PE-owned. The research comes as concerns about PE-owned hospitals are intensifying — from leaders both within and outside of the healthcare industry.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Astellas strikes $1.7bn SIRP drug deal with Elpiscience

pharmaphorum

Astellas has licensed up to four macrophage enhancer drugs with potential as cancer immunotherapies from Elpiscience in a $1.

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Novartis Returns to Voyager Therapeutics to Reach New Gene Therapy Destinations

MedCity News

Novartis is paying Voyager Therapeutics $100 million up front to collaborate on gene therapies for Huntington’s disease and spinal muscular atrophy. The deal builds on a relationship the companies started in 2022.

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Driving QbD as a quality standard in drug development

European Pharmaceutical Review

A paper published in the European Journal of Pharmaceutics and Biopharmaceutics has reviewed the current application status of Quality by Design (QbD) within the framework of the ICH guidelines (ICH Q8(R2) – Q14 and ICH Q2(R2)). Over the past several years, the pharmaceutical industry has faced challenges regarding quality assurance in drug development, the author asserted.

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AstraZeneca Reaches Agreement to Acquire Cell Therapy Specialist Gracell Biotechnologies

Pharmaceutical Commerce

Agreement includes novel cell therapy for hematology that has the opportunity to bring a potential best-in-class treatment to patients with blood cancers.

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How to Prove Marketing Value: Demonstrate Content ROI and Contribution to Sales

Every marketer knows how important it is to prove their efforts drive sales opportunities, but that’s easier said than done. When problems like sales and marketing misalignment, lack of data, and wasted efforts persist, marketers can’t measure, prove, or increase their impact on revenue at a time when demonstrating marketing value is critical. Using analyst and expert data, this guide to marketing impact and content attribution explains: How B2B buyers use content The most common types of conten

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Anavex hit as Rett syndrome drug flunks test

pharmaphorum

Shares in US biotech Anavex Life Sciences fell sharply this morning after Rett syndrome candidate Anavex 2-73 failed a phase 2/3 trial

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Financial factors to support and challenge Pharma in 2024

European Pharmaceutical Review

According to results from a survey by GlobalData, the top challenges for the pharmaceutical industry in 2024 will be inflation, geopolitical conflict and drug pricing pressures. Data outcomes revealed that most respondents from Pharma considered that drug pricing and reimbursement constraints will have a negative impact in 2024. Inflation and geopolitical pressure The second biggest negative impact was thought to be geopolitical conflicts and inflation.

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Novartis opens new frontier in Voyager gene therapy alliance

pharmaphorum

Novartis has doubled down on its gene therapy collaboration with Voyager Therapeutics, licensing candidates for Huntington's disease and SMA

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Proving It’s Clean with Analytics

PharmaTech

Analytical methods and tools play a pivotal role in cleaning validation.

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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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What New Year’s Resolutions and Organizational Change Have in Common

ALULA

Despite our best intentions, it’s widely known that over 75% of new year’s resolutions fail by the second week of February. While it’s hard enough to keep one’s own resolutions, advancing organizational change can be even more daunting. The very fundamentals of such work – securing effective sponsorship, supporting impacted employees, clearly articulating the finish line, etc. – are tricky to align and execute.

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'Faster, Please': Key Challenges in Chemicals and Materials R&D

PharmExec

Companies must address myriad challenges to improve upon issues such as data quality and transparency, process efficiency, and artificial intelligence/machine learning preparedness.

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AstraZeneca to advance haematology cell therapy

European Pharmaceutical Review

For an upfront price of $1.0 billion, AstraZeneca has agreed to acquire Gracell Biotechnologies, supporting the development of cell therapies in haematology and autoimmune diseases. Gracell’s FasTCAR-enabled B-cell maturation antigen (BCMA)/CD19 dual-targeting autologous CAR-T cell therapy GC012F, is an asset AstraZeneca will gain access to as part of the new acquisition agreement announced on 26 December 2023.

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AstraZeneca Bolsters Cellular Therapy Pipeline With Acquisition of Gracell Biotechnologies

PharmExec

Merger agreement includes the Gracell FasTCAR platform, which could significantly improve the efficacy of CAR T-cell therapies.

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Increase Revenue With Better, Faster Sales Onboarding

Quotas need to be hit. Revenue goals need to be met. This reality makes shortening sales onboarding time a top priority. Organizations with a standard onboarding process boost employee retention by 58% and increase productivity by 50%. Unfortunately, many companies struggle with inefficient processes that lead to high turnover and missed revenue opportunities.

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Choosing the Right Excipients for MSC and iPSC Therapies

PharmaTech

Buffers, stabilizers, and cryoprotectants play major roles in cell therapy formulations.

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Nearly three million people received urgent NHS cancer checks in 2023

PharmaTimes

The number of people getting tested over the last decade has increased by 133%

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Are You Ready for Inspection?

PharmaTech

Reviewing regulatory documents, such as 483 forms and Warning Letters, can aid in determining a facility’s inspection readiness, says Siegfried Schmitt, vice president, Technical at Parexel.

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Digital training programme improves quality of life for dementia patients living in care

PharmaTimes

The programme is the only remote, digital delivery nursing home training programme for dementia

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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Healthcare Marketing Trends in 2024: How to StayAhead

Healthcare Success

We hope your holiday season was filled with good cheer and plenty of new business opportunities. Now that the holidays have drawn to a close, it’s time to return to your 2024 marketing plan and make adjustments that ensure your business is taking advantage of the latest trends in healthcare marketing to reach patients and HCPs more effectively and make a lasting impression.

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Deep Brain Stimulation May Benefit Patients With Alzheimer Disease, But More Research Is Needed

Pharmacy Times

Patients who receive stimulation at different parts of the brain may reap benefits.

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The Monthly Marathon of a Sales Superstar

Contrarian Sales Techniques

Embarking on a new month in the sales world is like setting off on an exciting journey, with each phase offering its own unique challenges and opportunities. Let's map out the monthly routine of a sales superstar, broken down into early, mid, and end-of-month rituals. This isn't just about hitting targets. It's about creating a rhythm that keeps our sales champ at the top of their game.

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Immune Cells Shape Lung Development and Growth, Allow Developments for Treatment of Asthma, COPD

Pharmacy Times

The new understanding of immune cells could not only contribute to the development of lung disease treatments, but treatments for other organ systems as well.

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Using Generative AI in Sales: Pros, Cons, and Considerations According to Sellers

Are your sellers unsure about using AI in their day-to-day workflows? Or are they eager to try but uncertain where to start? They might be asking: Which tasks are best suited for AI? How will using AI affect my relationship with my customers? With so many tools available, which ones are the most useful to me? To help answer these and other common questions about using AI during the sales cycle, we surveyed B2B sellers who were early adopters to get their insight and advice about how to use gen A