Fri.Aug 02, 2024

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FDA signs off on Adaptimmune's Tecelra as the first engineered cell therapy for a solid tumor

Fierce Pharma

Adaptimmune has won accelerated FDA approval | Adaptimmune has won accelerated FDA approval for Tecelra (afami-cel), a treatment for metastatic or unresectable synovial sarcoma which becomes the first engineered cell therapy for a solid tumor and the first new treatment in the indication in more than a decade.

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Beyond Engineering: Integrating UX for Safer and More Efficient Medical Products

MedCity News

Many medtech products, very often too technical and scientific, emphasize features at the expense of processes and their interactions. While the approach to patient and treatment safety is crucial, there is a notable shift towards processes centered around patients and healthcare professionals. The post Beyond Engineering: Integrating UX for Safer and More Efficient Medical Products appeared first on MedCity News.

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Vertex lifts sales guidance as launch of gene therapy Casgevy picks up steam

Fierce Pharma

As growth in Vertex's cystic fibrosis portfolio buoys the company amid the launch of gene therapy Casgevy, the company is feeling confident enough to boost its revenue outlook for the year. | As of mid-July, around 20 patients completed the first step of Casgevy treatment by having their cells collected, up from five patients during the first quarter.

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Disrupting Trajectory of Chronic Kidney Disease Mortality Rates Through Digital Health Platforms

MedCity News

Digital solutions are changing the way CKD is managed. Through enhanced connectivity and personalized care plans tailored to individual patient needs, digital technologies allow patients to take proactive steps in managing CKD. The post Disrupting Trajectory of Chronic Kidney Disease Mortality Rates Through Digital Health Platforms appeared first on MedCity News.

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AI Strategies for Sales Managers: How to Cut Down on Tedious Admin Work

What if you could help your sellers stop wasting 72% of their day on non-selling activities and focus on bringing in revenue? Incorporating AI in your enablement workflows can help you cut down on busy work, get projects done faster, and let your team (and you!) focus on making a bigger impact. We put together this guide to show you how to use AI to cut time and costs for projects, including collateral creation, development of training videos, and automating tedious processes.

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Fierce Pharma Asia—Merck's surprise hiccup in China; Leqembi's slow ramp; Lawmakers' new biosecurity target

Fierce Pharma

Merck is trying to determine the reasons behind the surprise decline of Gardasil in China. Eisai and Biogen's Leqembi was rejected by European authorities amid a continued slow sales ramp. | Merck is trying to determine the reasons behind the surprise decline of Gardasil in China. Eisai and Biogen's Leqembi was rejected by European authorities amid a continued slow sales ramp.

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Lilly gets first heart outcomes readout with tirzepatide

pharmaphorum

Eli Lilly's dual GLP-1/GIP agonist tirzepatide has been shown to reduce the risk of worsening disease in people with heart failure and obesity in a phase 3 trial, the first to show a benefit on cardiovascular outcomes with the drug.

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FDA approves innovative engineered cell therapy

European Pharmaceutical Review

For the first time in over a decade, there is a new treatment option for patients with synovial sarcoma, a rare soft tissue cancer. The US Food and Drug Administration (FDA) has granted accelerated approval for the cell therapy TECELRA ® (afamitresgene autoleucel) to treat adults with unresectable or metastatic forms of the disease. Adaptimmune Therapeutics highlighted that TECELRA is a melanoma-associated antigen A4 (MAGE-A4)-directed genetically modified autologous T cell immunotherapy.

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Otsuka Pharmaceutical to Purchase Jnana Therapeutics

Pharmaceutical Commerce

In deal that has the potential to reach $1.1 billion, Otsuka aims to grow its drug pipeline, specifically in the field of rare and autoimmune diseases.

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Top-10 ways for Pharma to leverage AI according to…AI

Impetus Digital

A version of this article was previously published on PharmaPhorum. Like most people these days, I have been experimenting with various artificial intelligence (AI) tools this past year. It’s remarkable to see the progress made in the technology compared to only a few months ago and there are no signs of the progress slowing down. The pharmaceutical industry has numerous use cases for AI.

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Why Hospitals Are Decrying CMS’ New Inpatient Payment Rule

MedCity News

CMS finalized a rule this week that will boost hospitals’ inpatient payment rates by 2.9%. Hospitals groups are unhappy with this payment update, arguing that it is insufficient and will exacerbate hospitals’ financial challenges. The post Why Hospitals Are Decrying CMS’ New Inpatient Payment Rule appeared first on MedCity News.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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What pharma has learned from AI

PharmaVoice

As AI tools move from hype to a daily reality at pharma companies, here are the insights users are gaining.

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Adaptimmune’s FDA Approval Marks the First for an Engineered Cell Therapy for Solid Tumors

MedCity News

The FDA approved Adaptimmune Therapeutics’ Tecelra as a treatment for advanced cases of synovial sarcoma. It’s the first engineered cell therapy approved for treating a solid tumor. The post Adaptimmune’s FDA Approval Marks the First for an Engineered Cell Therapy for Solid Tumors appeared first on MedCity News.

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GSK bags sought-after Jemperli okay in endometrial cancer

pharmaphorum

FDA clears GSK's Jemperli as first-line therapy for all endometrial cancer patients, seen as key to driving sales above the $1bn threshold

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Researchers reveal CAR-enhancer therapy could help overcome cancer relapse

PharmaTimes

Cancer is estimated to affect more than three million people living in the UK, according to Macmillan Cancer Support

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How to Prove Marketing Value: Demonstrate Content ROI and Contribution to Sales

Every marketer knows how important it is to prove their efforts drive sales opportunities, but that’s easier said than done. When problems like sales and marketing misalignment, lack of data, and wasted efforts persist, marketers can’t measure, prove, or increase their impact on revenue at a time when demonstrating marketing value is critical. Using analyst and expert data, this guide to marketing impact and content attribution explains: How B2B buyers use content The most common types of conten

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AbbVie acquires Cerevel Therapeutics for $8.7bn

Pharmaceutical Technology

AbbVie has completed its acquisition of all outstanding shares of Cerevel Therapeutics in a deal valued at $8.7bn.

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FDA clears Adaptimmune T-cell therapy for soft tissue cancer

pharmaphorum

FDA has approved Adaptimmune's Tecelra for synovial sarcoma, the first engineered T-cell therapy for solid tumours

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Study reveals non-statin cholesterol drugs could reduce liver cancer risk

PharmaTimes

The third leading cause of cancer mortality accounts for over 700,000 deaths every year

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Sonde Health launches voice-based cognitive fitness tracker

pharmaphorum

Sonde Health has made a name for itself with the development of software that can detect illness from the sound of a patient's voice. Now, it has launched a dedicated app for tracking cognitive fitness, which it hopes may be able to spot signs of decline early.The app – Sonde Cognitive Fitness – allows users to monitor brain exertion in real-time by analysing vocal biomarkers using machine learning, an approach that is analogous to the use of fitness trackers to monitor physical and heart health

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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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Pharma Pulse 8/2/24: Overcoming Challenges to Drive Digital Customer Engagement, Mental Health Leaves of Absence Continue to Proliferate & more

Pharmaceutical Commerce

The latest news for pharma industry insiders.

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FDA Expands Approval of GSK’s Jemperli in Combination with Chemotherapy for Adults with Primary Advanced or Recurrent Endometrial Cancer

PharmExec

Approval marks the first time an immuno-oncology regimen has demonstrated a survival benefit for all adults with primary advanced or recurrent endometrial cancer, company says.

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Optimizing HCP Engagement: The Power of Timely, Precise, and Actionable Patient Alerts

Prognos Health

Effective HCP engagement is a cornerstone of successful pharmaceutical marketing. The right information, delivered at the right moment to the right HCP with a brand eligible patient, can significantly influence treatment decisions and drive brand growth. However, many pharmaceutical marketing teams grapple with patient alert solutions that are limited in scope, accuracy, or geographic reach.

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Obstacles Facing Biologics Preservation

Pharmaceutical Commerce

In this part of his Pharma Commerce video interview, Dan Gagnon, UPS Healthcare’s VP of Global Strategy & Acquisition Integration, dives into the challenges of safeguarding these products, while also sharing his keys to sustaining stability in the ‘recession resistant’ healthcare industry.

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Increase Revenue With Better, Faster Sales Onboarding

Quotas need to be hit. Revenue goals need to be met. This reality makes shortening sales onboarding time a top priority. Organizations with a standard onboarding process boost employee retention by 58% and increase productivity by 50%. Unfortunately, many companies struggle with inefficient processes that lead to high turnover and missed revenue opportunities.

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Informing Organon’s Strategic Approach From an OB-GYN POV

PharmExec

In this part of her Pharmaceutical Executive video interview, Charlotte Owens, MD, FACOG, Head of Medical Affairs and Outcomes Research at Organon, discusses how she's using her in-practice experience as an OB-GYN to inform Organon's strategic approach to addressing maternal health challenges.

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Going Green: Updating Your Filings

PharmaTech

The implementation of new quality control methods must be reported to regulators, says Susan J. Schniepp, distinguished fellow at Regulatory Compliance Associates.

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Casgevy: Launch sequence and price analysis of the first marketed CRISPR therapy

Pharmaceutical Technology

In 2023, Casgevy was approved in the US to treat sickle cell disease (SCD), making it the first FDA-approved gene therapy to use CRISPR-based gene editing.

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Understanding IDNs and What They Mean to the Pharmaceutical Industry–Q&A with Greg Skalicky

PharmExec

OncLive serves as the connection to oncology, including groundbreaking cancer news and interviews with top oncologists in multimedia formats.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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Merck buys Mirus Bio to boost viral vector bioprocessing capacity

Pharmaceutical Technology

Merck KGaA has concluded the acquisition of Mirus Bio for €500m ($600m), enhancing its viral vector bioprocessing capabilities.

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FDA Grants Accelerated Approval to Adaptimmune Therapeutics’ Tecelra for Adults with Synovial Sarcoma Who Have Undergone Prior Chemotherapy

PharmExec

OncLive serves as the connection to oncology, including groundbreaking cancer news and interviews with top oncologists in multimedia formats.

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Adaptimmune’s Tecelra gains accelerated approval for synovial sarcoma

Pharmaceutical Technology

The MAGE-A4-targeted genetically modified T cell therapy is indicated for the treatment of synovial sarcoma.

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Blue Shield of California Offers Blue Zones Challenge App to Members

PharmExec

OncLive serves as the connection to oncology, including groundbreaking cancer news and interviews with top oncologists in multimedia formats.

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Using Generative AI in Sales: Pros, Cons, and Considerations According to Sellers

Are your sellers unsure about using AI in their day-to-day workflows? Or are they eager to try but uncertain where to start? They might be asking: Which tasks are best suited for AI? How will using AI affect my relationship with my customers? With so many tools available, which ones are the most useful to me? To help answer these and other common questions about using AI during the sales cycle, we surveyed B2B sellers who were early adopters to get their insight and advice about how to use gen A