Tue.Oct 22, 2024

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Pfizer lays off 75 more workers in North Carolina in wake of late-stage DMD trial fail

Fierce Pharma

Pfizer has told 75 employees in Sanford, North Carolina, that their positions have been eliminated. | Pfizer has told 75 employees in Sanford, North Carolina, that their positions have been eliminated. The layoffs come three months after the company axed 150 positions in Sanford following a high-profile phase 3 trial failure for its Duchenne muscular dystrophy gene therapy candidate.

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Avandra Imaging Emerges from Stealth to Solve a Last-Mile Problem in Medical Research

MedCity News

Avandra Imaging, a federated network for de-identified imaging data, emerged from stealth at HLTH — as well as announced a partnership with Datavant. The post Avandra Imaging Emerges from Stealth to Solve a Last-Mile Problem in Medical Research appeared first on MedCity News.

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Starboard wants to hold Pfizer leadership 'accountable' for overpaid M&A deals, poor return on R&D investment

Fierce Pharma

Activist investor Starboard Value is baring its teeth at Pfizer management, more openly going after CEO Albert Bourla’s job. | Activist investor Starboard Value is baring its teeth at Pfizer management, more openly going after CEO Albert Bourla’s job in a new presentation.

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Otsuka eyes early filing of IgAN drug after phase 3 readout

pharmaphorum

Otsuka is hoping to file for approval of its anti-APRIL antibody sibeprenlimab as a treatment for kidney disorder IgA nephropathy (IgAN) after the drug hit the target in a phase 3 trial.The Japanese drugmaker said that interim results from the 530-patient VISIONARY study showed that sibeprenlimab achieved a statistically significant and clinically meaningful reduction in 24-hour urine protein-to-creatine ratio (uPCR) – a measure of how well the kidneys are working – after nine months of treatmen

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AI Strategies for Sales Managers: How to Cut Down on Tedious Admin Work

What if you could help your sellers stop wasting 72% of their day on non-selling activities and focus on bringing in revenue? Incorporating AI in your enablement workflows can help you cut down on busy work, get projects done faster, and let your team (and you!) focus on making a bigger impact. We put together this guide to show you how to use AI to cut time and costs for projects, including collateral creation, development of training videos, and automating tedious processes.

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DOJ challenges Johnson & Johnson's talc bankruptcy attempt in Texas

Fierce Pharma

With Johnson & Johnson sweetening the pot and mustering up the support of 83% of those who claim that the company’s talc products caused their cancer, it had

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Analyzing the Medicare Advantage Terminations: Concerns, Drivers, and Solutions

MedCity News

Both providers and payers face challenges and understanding the requirements and needs of each stakeholder has the potential to lower the temperature of the current rhetoric. The post Analyzing the Medicare Advantage Terminations: Concerns, Drivers, and Solutions appeared first on MedCity News.

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AZ, Ionis get CHMP backing for ATTR polyneuropathy drug

pharmaphorum

AstraZeneca and Ionis are on track for EU approval of ATTR polyneuropathy therapy Wainzua after the CHMP backs the drug

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CDMO Samsung Biologics bags $1.2B production contract, bringing total 2024 deal value to $3.3B+

Fierce Pharma

With multiple high-profile production pacts already in the books for 2024, CDMO Samsung Biologics has hooked another big one. | Following a string of high-profile deals, Samsung Biologics has locked down a $1.2 billion contract with an unnamed Asia-based pharmaceutical company that’s expected to run through December 2037. Samsung did not elaborate on the identity of its new partner or the types of drugs it will help produce under the accord.

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The Case for Prioritizing the Number One Killer: Cardiovascular Disease

MedCity News

Highly preventable if diagnosed and managed early, CAD should be a healthcare priority. Both patients and providers have pivotal roles in driving this change. The post The Case for Prioritizing the Number One Killer: Cardiovascular Disease appeared first on MedCity News.

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Telix unveils radiopharmaceutical spinoff Rhine Pharma following string of nuclear medicine acquisitions

Fierce Pharma

There’s no denying it: the radiopharmaceuticals boom is here to stay. | Telix on Tuesday unveiled the spin-off of Rhine Pharma—a new entity born from a collaboration between Telix and Germany’s Heidelberg University Hospital—which is setting out on a mission to expand access to radiopharmaceuticals for cancer treatment and imaging.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Editas Medicine Seeks Partner for Ex Vivo Gene-Editing Program as Focus Turns to In Vivo R&D

MedCity News

Editas Medicine says its in vivo gene-editing therapy for hemoglobinopathies has best-in-class potential, but the company plans to out-license or partner that program. Editas is shifting focusing to in vivo gene-editing therapies. The post Editas Medicine Seeks Partner for Ex Vivo Gene-Editing Program as Focus Turns to In Vivo R&D appeared first on MedCity News.

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Amid geopolitical risk, Legend sheds Genscript as majority shareholder

Fierce Pharma

Legend Biotech has managed to remove Genscript Biotech as its majority shareholder, just as the former parent’s Chinese background falls under a U.S. biosecurity microscope. | Legend Biotech has managed to remove Genscript Biotech as its majority shareholder, just as the former parent’s Chinese background falls under a U.S. biosecurity microscope.

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Chelsea Clinton on Reproductive Rights: 3 Things to Know

MedCity News

During a panel discussion at HLTH, Chelsea Clinton shared three things she wants healthcare leaders to know going into the election when it comes to reproductive health. The post Chelsea Clinton on Reproductive Rights: 3 Things to Know appeared first on MedCity News.

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The pulse of the medtech industry

Fierce Pharma

EY recently published their 18th annual Pulse of the MedTech Industry report, highlighting | This week on "The Top Line," Fierce Medtech's Conor Hale dives into EY's 18th annual Pulse of the MedTech Industry report and chats with EY's John Babbitt about the team's findings and the pace of M&A, venture capital funding and recent IPOs.

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How to Prove Marketing Value: Demonstrate Content ROI and Contribution to Sales

Every marketer knows how important it is to prove their efforts drive sales opportunities, but that’s easier said than done. When problems like sales and marketing misalignment, lack of data, and wasted efforts persist, marketers can’t measure, prove, or increase their impact on revenue at a time when demonstrating marketing value is critical. Using analyst and expert data, this guide to marketing impact and content attribution explains: How B2B buyers use content The most common types of conten

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EU CHMP recommends AstraZeneca and Ionis’ Wainzua for ATTRv-PN

Pharmaceutical Technology

The European Union's CHMP has recommended the approval of AstraZeneca and Ionis Pharmaceuticals’ Wainzua to treat ATTRv-PN.

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France warns of penalties if Opella production goes offshore

pharmaphorum

Sanofi is now in exclusive talks with private equity company Clayton Dubilier & Rice over the sale of a controlling stake in its consumer health business Opella, as the French government seeks guarantees it will keep production and jobs in France.

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CHMP Gives Positive Opinion to Novo Nordisk Hemophilia Treatment

PharmaTech

As many as 30% of people living with severe hemophilia A develop inhibitors such as TFPI, which can be produced by the body’s immune response to clotting factors in replacement therapy, often limiting the effectiveness of that therapy.

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Europe's share of clinical trials falling, with China rising

pharmaphorum

The proportion of commercially sponsored clinical trials run in Europe almost halved over the last 10 years and is now trailing China

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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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MangoRx hits back at Eli Lilly’s weight loss drug copycat claims

Pharmaceutical Technology

Eli Lilly sued three online vendors and medical spas earlier this week over improper copying of tirzepatide.

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Starboard spells out its concerns with Pfizer's direction

pharmaphorum

Starboard Value CEO Jeff Smith pulls no punches in his assessment of Pfizer failings, which he claims have resulted in at least $20bn in lost value

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Editas and Genevant team up to develop gene editing therapies

Pharmaceutical Technology

Editas is partnering its CRISPR platform with Genevant’s LNP technology to develop novel gene editing medicines in a deal worth $283m.

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World-first medicine manufacturing regulatory framework to be implemented

European Pharmaceutical Review

The UK is set to be the first country to introduce a new regulatory framework for innovative products manufactured at or close to the point of patient care, says the Medicines and Healthcare products Regulatory Agency (MHRA). This Statutory Instrument means that patients can access highly personalised medicines and medicines with a very short shelf life more quickly.

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Increase Revenue With Better, Faster Sales Onboarding

Quotas need to be hit. Revenue goals need to be met. This reality makes shortening sales onboarding time a top priority. Organizations with a standard onboarding process boost employee retention by 58% and increase productivity by 50%. Unfortunately, many companies struggle with inefficient processes that lead to high turnover and missed revenue opportunities.

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Valneva Scotland announces year-long support for local cancer charity Team Jak

PharmaTimes

The company’s workforce will volunteer and fundraise for Team Jak throughout the year

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2024 PharmaVoice 100s: Patient Champions

PharmaVoice

Leaders advancing health advocacy, DEI initiatives and better medicine access for patients.

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Novo Nordisk plans label expansion for Rybelsus following Phase III win

Pharmaceutical Technology

The oral semaglutide reduced the occurrence of major adverse cardiovascular events (MACE) by 14% in patients with type 2 diabetes.

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Access Insights 2024: The State of Retail Pharmacy

Pharmaceutical Commerce

Bill Roth, General Manager, Managing Partner, Blue Fin Group, discusses key takeaways of the breakout session.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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How pharma leaders are approaching digital transformation

Pharmaceutical Technology

For firms unsure about the digital transition, partnering with experienced providers like Controlant simplifies the process

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Elevating Patient Experiences by Breaking Down Internal Silos

PM360

In the pharmaceutical industry, patient support programs (PSPs) and brand teams often work in silos, despite their shared goal of helping patients achieve a certain health outcome. This division of labor is typical in complex and highly regulated industries, but departmental divides can come at a cost. These silos often act as a barrier to sharing important information and best practices.

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Cambridge University and GSK sign immunology R&D collaboration

Pharmaceutical Technology

GSK has announced a £50m ($54.3m) investment in a partnership with the University of Cambridge to expedite R&D in immune-related diseases.

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With activist investment rising, Pfizer’s battle with Starboard reflects the industry’s post-pandemic tumble

PharmaVoice

Pfizer’s proxy battle with Starboard has gotten messy. It’s the latest in a series of activist investor campaigns that have been on the rise in recent years.

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Using Generative AI in Sales: Pros, Cons, and Considerations According to Sellers

Are your sellers unsure about using AI in their day-to-day workflows? Or are they eager to try but uncertain where to start? They might be asking: Which tasks are best suited for AI? How will using AI affect my relationship with my customers? With so many tools available, which ones are the most useful to me? To help answer these and other common questions about using AI during the sales cycle, we surveyed B2B sellers who were early adopters to get their insight and advice about how to use gen A