Mon.Jul 22, 2024

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Sinking prices for generic meds a major factor in US shortage crisis: report

Fierce Pharma

As lawmakers and industry groups seek to get a handle on U.S. | As lawmakers and industry groups seek to get a handle on U.S. drug shortages, a new white paper from German market analytics firm QYOBO supports the thesis that disproportionately low prices for generic medicines can make it difficult for drugmakers to keep supplies afloat.

Medicine 266
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How NVIDIA grew with the healthcare market instead of pushing into it

Pharmaceutical Technology

As the use of AI soared across healthcare, NVIDIA fit the bill in providing the necessary technology – and its stock tells the same story.

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Agilent Technologies lays out $925M to acquire Canadian specialty CDMO Biovectra

Fierce Pharma

After changing hands several times throughout the 2010s, Canadian specialty contract development and manufacturing organization (CDMO) Biovectra has agreed to fly the Agilent flag. | Agilent has revealed that it’s signed a definitive agreement to acquire Biovectra for $925 million through a mix of cash and debt financing. The deal is expected to close this year.

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In This Round, Humans 1, AI LLMs 0

MedCity News

Anthropic’s Claude3-Opus performed better than GPT-4, but both fell short of humans on a test of objective medical knowledge. The study was conducted by a firm developing LLMs specifically for healthcare that claim to be incorporating peer-reviewed sources of information. The post In This Round, Humans 1, AI LLMs 0 appeared first on MedCity News.

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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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President Biden touts drug pricing achievements as he steps down from re-election campaign

Fierce Pharma

At his vacation home in Delaware, President Joe Biden made the striking announcement that he is dropping out of the 2024 | While President Joe Biden is officially out for the 2024 election, his term has certainly made a mark in the healthcare realm.

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Neuro Drug Passed Up by Biogen Posts Positive Data for Ionis, Setting Stage for Phase 3 Test

MedCity News

Ionis Pharmaceuticals is looking ahead to a Phase 3 study for an antisense medicine it is developing to treat Angelman syndrome, a rare neurodevelopmental disorder with no FDA-approved therapies. Its main competition is an Ultragenyx Pharmaceutical drug set to begin pivotal testing later this year. The post Neuro Drug Passed Up by Biogen Posts Positive Data for Ionis, Setting Stage for Phase 3 Test appeared first on MedCity News.

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Home Dialysis Advances Will Make Transplant Wait a Little Easier

MedCity News

For folks on the transplant waiting list, the wait from now on should be less disruptive. Life should be more pleasant. And all things being equal, one’s condition going into a transplant should be better. The post Home Dialysis Advances Will Make Transplant Wait a Little Easier appeared first on MedCity News.

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Bluebird bio's gene therapy fertility support program gets thumbs down from HHS inspector general

Fierce Pharma

The door is closing on bluebird bio’s attempt to secure Medicaid coverage for its fertility support program, which is already offered to patients with commercial insurance who receive its gene ther | The door is closing on bluebird bio’s attempt to secure Medicaid coverage for its fertility support program, which is already offered to patients with commercial insurance who receive its gene therapies.

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10 Proven Sales Appointment Setting Tips (With Script)

Spotio

In both inside and outside sales environments, a lot of emphasis is placed on nurturing leads and closing deals. And while those steps are crucial when it comes to locking down new clients, improving your team’s activity-to-appointment ratio should also be a priority. The first step toward closing a deal is getting a prospect to commit to that first appointment, after all.

Sales 98
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Vitable Secures $16M To Provide Primary Care to Small Employers

MedCity News

Vitable’s $16 million Series A funding round was led by Cherryrock Capital and included participation from newark venture partners, Citi Impact Fund, First Round Capital, Commerce Ventures and Y Combinator. In total, Vitable has raised more than $25 million. The post Vitable Secures $16M To Provide Primary Care to Small Employers appeared first on MedCity News.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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How a potential Harris presidency could influence US healthcare

Pharmaceutical Technology

As VP Kamala Harris enters the presidential race, her strong stances for reproductive rights and drug access offer insights into future actions.

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The Pediatric Innovation Landscape

MedCity News

Pediatric mental health is the theme of the Pitch Perfect contest at the INVEST Digital Health conference at Pegasus Park in Dallas on September 18. Here’s a look at some of the pediatric mental health companies to watch. The post The Pediatric Innovation Landscape appeared first on MedCity News.

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How NIVIDIA grew with the healthcare market instead of pushing into it

Pharmaceutical Technology

As the use of AI soared across healthcare, NVIDIA fit the bill in providing the necessary technology – and its stock tells the same story.

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The Future of Birth Control: No Hormones, More Options for Men

MedCity News

The advancement, adoption of, and access to these options – regardless of age, geography, and financial considerations – requires the support of the scientific community, drug developers, funders, regulatory agencies, insurers, and lawmakers to make the concept of a hormone-free future a reality. The post The Future of Birth Control: No Hormones, More Options for Men appeared first on MedCity News.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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Study finds wearables deliver key insights in heart disease

pharmaphorum

Consumer wearables have shown a benefit when used to monitor treatment responses in patients with atrial fibrillation and heart failure.

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Best Practices in Achieving Revenue Cycle Excellence 

MedCity News

Discover the best practices in revenue cycle management to enhance financial health and streamline administrative processes in healthcare. The post Best Practices in Achieving Revenue Cycle Excellence appeared first on MedCity News.

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New study shows wearable trackers provide clinical use for heart disease patients

PharmaTimes

Cardiovascular disease, including coronary heart disease, currently affects around seven million people in the UK

Patients 103
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Implementing Inclusivity: Putting Clinical Trial Equity Into Practice

MedCity News

In the realm of inclusivity and equity, planning early and engaging key stakeholders throughout the process makes it possible to make these changes while also safeguarding participants. How can researchers put clinical trial equity into practice? The post Implementing Inclusivity: Putting Clinical Trial Equity Into Practice appeared first on MedCity News.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Study points to route for 'one and done' flu vaccine

pharmaphorum

Scientists at OHSU in the US have developed a universal form of influenza vaccine that they say could protect against all strains of the virus

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EMA accepts GSK’s Blenrep MAA for multiple myeloma for review

Pharmaceutical Technology

The EMA has accepted for review GSK’s MAA for Blenrep for relapsed or refractory multiple myeloma (r/r MM).

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Valneva gets $41m grant to roll out chikungunya vaccine

pharmaphorum

Valneva has been awarded funding from the Coalition for Epidemic Preparedness Innovations (CEPI) and EU to expand access to its recently approved vaccine for chikungunya, a potentially life-threatening mosquito-borne disease.

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Trial investigates faecal microbiota transplantation to treat rare liver disease

PharmaTimes

Primary sclerosing cholangitis is estimated to affect one in 100,000 people worldwide annually

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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Grünenthal buys Valinor and constipation drug for $250m

pharmaphorum

Pain medicine specialist Grünenthal has agreed to buy Valinor Pharma for $250m, getting control of Movantik for opioid-induced constipation

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Pharma Pulse 7/22/24: Global Diabetes & Obesity Therapeutics Study, Is There a Correlation Between Medical Debt and Delayed Mental Health Care? & more

Pharmaceutical Commerce

The latest news for pharma industry insiders.

Pharma 105
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Innovent throws its hat further into China's GLP-1 ring

pharmaphorum

Innovent Biologics is planning a second filing for its dual GLP-1/glucagon agonist mazdutide in China, as it tries to carve out a share of a market currently dominated by Novo Nordisk and Eli Lilly.Mazdutide – a once-weekly injectable Innovent licensed from Lilly – was submitted to China's National Medical Products Administration (NMPA) earlier this year for weight management in overweight and obesity, and will soon be submitted for type 2 diabetes as well after a second positive phase 3 trial,

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Medical Sales Targeting (Part 4) 

Cesare Ferrari

One of the challenges in medical sales is disseminating the right messages to the right doctors at the right time. Previously, I discussed how to identify the right customer and pass the right message ; today’s post will focus on when to pass the message, knowing fully well that timing is critical. This is equally because the degree of difficulty of the “targeting at right time” challenge is unique to each specific message, campaign and customer.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Micro-Dosing: The Powder in Capsule Technology Pathway from Development to Commercialization

PharmaTech

Accelerating a drug’s journey through early-phase development to commercialization can be made easy with precision equipment. Precision micro-dosing and powder-in-capsule (PIC) technology can help accelerate clinical trials supply and seamless scaling up from clinical to commercial manufacturing.

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How Legal Teams Enforce HIPAA Compliant Digital Ads

Penrod

Make sure your marketing team complies with the Ad Platform’s internal policies Apart from government regulations like HIPAA, the first barrier to risk are the guidelines of your ad platforms. Most digital ad platforms have internal policies specifically written for healthcare-based advertising. Restrictions are particularly stringent when it comes to pharmaceutical companies, but each platform has its own policies that must be adhered to.

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Demystifying the 5G standard essential patent landscape: Phase 5

Clarivate

A new report [1] from Clarivate patent experts provides an update on 5G standards-essential patent declarations. In our Demystifying the 5G standard essential patent landscape: Phase 4 report published in June 2023, we presented the statistics of patents declared as essential to 5G standards as of December 31, 2022. In this new report, we present statistics that capture new declarations, new 5G standards, new patent applications and new grants within the patent families.

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Braeburn on BRIXADI® Research and Addressing Fentanyl's Impact on OUD

PharmExec

In this part of his Pharmaceutical Executive video interview, Joshua M. Cohen, MD, MPH, FAHS, Chief Medical Officer, Braeburn discusses data from the Phase III trial recently published in JAMA and how confident they are in the generalizability of these findings to a real-world treatment setting.

Medical 52
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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.