Thu.Mar 21, 2024

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Despite positive trial, Roche says Enspryng fell short of expectations in myasthenia gravis

Fierce Pharma

Drug developers often try to spot tidbits of positive information from a failed clinical trial. | Drug developers often try to spot tidbits of positive information from a failed clinical trial. But Roche is doing the opposite for its positive Enspryng study in the competitive autoimmune disorder of myasthenia gravis.

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Capital Rx, Prime Therapeutics Form Strategic Alliance

MedCity News

Through a new strategic alliance, Prime Therapeutics will be the only PBM — aside from Capital Rx — to use Capital Rx’s JUDI platform.

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GSK joins AstraZeneca, Boehringer in capping US out-of-pocket inhaler prices at $35 per month

Fierce Pharma

Amid congressional scrutiny on U.S. | The drugmaker's commitment will start by January 1, 2025, and follows similar moves by peers Boehringer Ingelheim and AstraZeneca. Before the pledges, the companies—and Teva—caught Senate heat over high U.S. inhaler prices.

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Why Health System Execs Say You Can’t Separate ‘Patient’ from ‘Consumer’

MedCity News

Many people don’t take well to the term “healthcare consumer,” or have expressed that they prefer to be referred to as a patient rather than a consumer. But in the U.S., it’s a plain fact that people have choices when it comes to their healthcare. In this piece, three health system executives give their take on why “patient” and “consumer” are often one in the same — and why hospitals need to be mindful of this.

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AI Strategies for Sales Managers: How to Cut Down on Tedious Admin Work

What if you could help your sellers stop wasting 72% of their day on non-selling activities and focus on bringing in revenue? Incorporating AI in your enablement workflows can help you cut down on busy work, get projects done faster, and let your team (and you!) focus on making a bigger impact. We put together this guide to show you how to use AI to cut time and costs for projects, including collateral creation, development of training videos, and automating tedious processes.

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Fierce Pharma Asia—Plant expansions at Novo, Novartis, Merck KGaA; Kyowa Kirin's pricing record; BeiGene's PD-1 nod

Fierce Pharma

Three large pharma companies plan to expand their manufacturing footprints. Kyowa Kirin’s $4.25 million gene therapy set a new world pricing record. | Three large pharma companies plan to expand their manufacturing footprints. Kyowa Kirin’s $4.25 million gene therapy set a new world pricing record. BeiGene’s PD-1 inhibitor finally crossed the FDA finish line after a 20-month delay.

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Precision Medicine Startup Mirador Unveils $400M for R&D of New I&I Drugs

MedCity News

Mirador Therapeutics applies machine learning to human data to discover new immunology and inflammation drugs. The startup’s management includes several from the executive team of Prometheus Biosciences, an immunology biotech bought by Merck last year.

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Parkinson’s UK grants funding of up to nearly £450,000 to four new research projects

PharmaTimes

The globally fast-growing progressive neurological condition affects around 153,000 people in the UK

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Merck’s Lynparza-Keytruda combo sputters in 2nd lung cancer trial. Will an ADC pairing work instead?

Fierce Pharma

Merck’s attempt to use Lynparza to boost Keytruda in metastatic non-small cell lung cancer has come up short with a second pivotal trial failure. | Merck’s attempt to use Lynparza to boost Keytruda in metastatic non-small cell lung cancer has come up short with a second pivotal trial failure.

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MS research network taps Seqster for data sharing

pharmaphorum

Novartis-supported multiple research project will use Seqster's data-sharing platform to support R&D and evidence-based care

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In his swan song at Bristol Myers Squibb, former CEO Giovanni Caforio pulled down $19.7M

Fierce Pharma

In his final year as CEO at Bristol Myers Squibb, Giovanni Caforio took a slight dip in pay to $19.7 million, down from the $20.1 million he collected in 2022, according to the company’s | In his final year as CEO at Bristol Myers Squibb, Giovanni Caforio took a slight dip in pay to $19.7 million, down from the $20.1 million he collected in 2022.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Required: A Commitment to Funding State Child Psychiatry Access Programs

MedCity News

Surgeon General Vivek Murthy recently described mental health as “the defining public health crisis of our time.” No crisis can be tackled without the proper tools. As the burden of mental and behavioral illness continues to rise, now is the time to invest in the future well-being of our population.

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Clasp emerges with $150m for safer T cell engagers

pharmaphorum

Clasp Therapeutics has burst onto the T-cell engager (TCE) scene with $150 million in funding for a platform that aims to improve the safety of the class, which is currently gaining traction in cancer immunotherapy.

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Patient centricity for tailor-made healthcare

European Pharmaceutical Review

Can you tell us a bit about yourself and your role at Pfizer? I’m a pharmacist with an MBA and PhD. My PhD thesis is about considerations in the production and purchasing of drugs. I joined Pfizer in January 2023 as a health access specialist, after working at Clalit Health Services in Israel for almost 20 years. At Clalit, which is the second largest healthcare provider in the world, I worked in several management positions and gained a broad understanding of the needs and constraints of a heal

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Eisai backs Leqembi’s Japan rollout with insurance policy

pharmaphorum

A partnership between Eisai and Lifenet that aims to improve insurance cover for people with early dementia has generated its first policy, part of an effort by the pharma group to develop an ‘ecosystem’ to support patients.

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How to Prove Marketing Value: Demonstrate Content ROI and Contribution to Sales

Every marketer knows how important it is to prove their efforts drive sales opportunities, but that’s easier said than done. When problems like sales and marketing misalignment, lack of data, and wasted efforts persist, marketers can’t measure, prove, or increase their impact on revenue at a time when demonstrating marketing value is critical. Using analyst and expert data, this guide to marketing impact and content attribution explains: How B2B buyers use content The most common types of conten

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Bionomics to advance non-SSRI PTSD candidate to Phase III

Pharmaceutical Technology

Bionomics plans to meet with the FDA following positive topline data from the Phase IIb ATTUNE trial of the post-traumatic stress disorder (PTSD) drug BNC210.

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Scientists hail first pig-to-man kidney transplant

pharmaphorum

Surgeons in the US have carried out the world’s first transplant of a pig kidney into a human, a feat made possible by genetic modification of the organ and an experimental immunosuppressant drug regimen to prevent rejection. The recipient, 62-year-old Richard Slayman of Weymouth in Massachusetts, had end-stage renal disease and was dependent on dialysis.

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Merck to invest €300m in South Korean bioprocessing centre

Pharmaceutical Technology

Merck KGaA has announced an investment of over €300m ($326.1m) to establish a new bioprocessing production centre in Daejeon, South Korea.

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UK advanced therapies to get £17.9 million boost

European Pharmaceutical Review

A new £17.9 million strategic initiative is set to support UK advanced therapy medicinal product (ATMP) clinical trials, and help the region maintain its position as a leader in clinical research. An additional four years of funding for the Advanced Therapy Treatment Centre ( ATTC ) network is available through this programme. Collaborators include the National Institute for Health and Care Research (NIHR), Innovate UK, the ATTC network and the Cell and Gene Therapy Catapult (CGT Catapult).

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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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PAP 2024: The Glass is Half Full

Pharmaceutical Commerce

A multiple myeloma survivor shares his story, including how patient assistance made a positive impact.

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BMS’ cell therapy Abecma gains EC approval for multiple myeloma

Pharmaceutical Technology

The EC has approved BMS' Abecma (idecabtagene vicleucel; ide-cel) to treat adults with relapsed and refractory multiple myeloma (RRMM).

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Control strategy could facilitate faster bioburden detection

European Pharmaceutical Review

Biopharma and bioprocessing experts have proposed an approach that uses a two-tiered control strategy for rapid bioburden testing, that can beneficially, “leverage faster detection times”. It comprises of a “fast (but possibly less sensitive) test” for process monitoring which then initiates “action for a second, longer duration test which is used to confirm and quantify the presence of bioburden and identify the [ microbial ] organism.

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Delivery tech remains challenging with gene therapies for brain disorders

Pharmaceutical Technology

Biotech executives discuss why developing gene therapies for central nervous system disorders remains difficult at a recent conference.

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Increase Revenue With Better, Faster Sales Onboarding

Quotas need to be hit. Revenue goals need to be met. This reality makes shortening sales onboarding time a top priority. Organizations with a standard onboarding process boost employee retention by 58% and increase productivity by 50%. Unfortunately, many companies struggle with inefficient processes that lead to high turnover and missed revenue opportunities.

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An ocean of answers in a single cell — how proteomics can lead to better drugs

PharmaVoice

New tools that allow researchers to separate single cells can help map the complex web of proteins that lead to disease, providing new targets for biopharma.

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Capstan secures $175m Series B funds for CAR-T therapy

Pharmaceutical Technology

Capstan Therapeutics has secured $175m Series B financing to advance its lead in vivo CAR-T candidate, CPTX2309, for autoimmune disorders.

Leads 98
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UK Government Bans 15 Synthetic Opioids

PharmaTech

More synthetic opioids have been placed under the strictest controls in the United Kingdom.

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Researchers reveal protein found in human sweat could protect against Lyme disease

PharmaTimes

The bacterial infection transmitted by ticks affects nearly half a million people in the US every year

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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How Integrated Real-World Data Leads to More Meaningful Results

MedCity News

In order to understand the current state of the healthcare system it is essential to have comprehensive sources of real-world and integrated data linked with data from across the healthcare ecosystem.

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Nouscom extends Series C round to $82m for cancer vaccine trials

Pharmaceutical Technology

Nouscom is part of a cancer vaccine landscape that has recently jump-started following years of dormancy.

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Guth named COO as Bayer revamps top pharma team

pharmaphorum

Bayer cuts its pharma management, with Sebastian Guth promoted to chief operating officer and Christine Roth heading a new commercial unit

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Study Data Suggests Sustained Safety, Efficacy of Lanadelumab in Adolescents With HAE

Pharmacy Times

The data comes from 2 phase 4 trials, ENABLE and EMPOWER, which evaluated lanadelumab and the outcomes of treatment in adolescents with hereditary angioedema.

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Using Generative AI in Sales: Pros, Cons, and Considerations According to Sellers

Are your sellers unsure about using AI in their day-to-day workflows? Or are they eager to try but uncertain where to start? They might be asking: Which tasks are best suited for AI? How will using AI affect my relationship with my customers? With so many tools available, which ones are the most useful to me? To help answer these and other common questions about using AI during the sales cycle, we surveyed B2B sellers who were early adopters to get their insight and advice about how to use gen A