Wed.Feb 07, 2024

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Gilead plots long-term cell therapy growth, maintains confidence in Trodelvy despite trial miss

Fierce Pharma

Despite markedly slower cell therapy growth from the third to the fourth quarter of 2023—and a recent setback for Trodelvy—historically HIV-focused Gilead Sciences is not discouraged amid its | Despite a tame level of fourth-quarter growth, recent advances should drive long-term cell therapy sustainability, Gilead execs said. Overall, the company is pushing to generate 30% of its revenues from oncology by 2030.

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Increasing the Impact of Opioid Settlement Funds by Investing in Health IT Infrastructure

MedCity News

Strengthening health IT infrastructure is a critical and necessary step toward abating the opioid crisis and evaluating the impact of how opioid settlement dollars are allocated across communities.

Pharma 127
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Eisai, Biogen likely to miss early launch goal for Alzheimer's drug Leqembi

Fierce Pharma

Even with Leqembi now sporting a full FDA approval and benefiting from the simpler Medicare coverage that distinction brings, Eisai and Biogen’s latest Alzheimer’s disease med appears to be moving | While Japan’s Eisai had set the goal to reach 10,000 patients with Leqembi by the end of its 2024 fiscal year, which wraps up in March, only 2,000 patients in the U.S. were receiving the amyloid-busting antibody as of Jan. 26, Eisai explained in a third-quarter earnings presentation.

FDA 220
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Why Are Hospitals Fighting Site-Neutral Payments So Fervently?

MedCity News

Establishing site-neutral payments for outpatient services is a hot issue in Capitol Hill right now. Advocates say that such policy would lower healthcare costs, saving both patients and taxpayers money. Opponents say that it would put hospitals’ financial security at risk and jeopardize access to care.

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How to Create Sales Email Sequences That Convert

Modern go-to-market teams know it takes more than one email to break through the noise. Multiple touchpoints means more ways to get your pitch right — and, potentially, more ways to be wrong. The good news? Once you know how to write compelling, one-off emails to entice prospective customers, you can easily do the same across a short sequence of emails.

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Catalent receives another regulatory wrist slap at Indiana plant included in Novo buyout

Fierce Pharma

As part of the acquisition of manufacturing giant Catalent, Novo Nordisk will fork over $11 billion for three of the CDMO’s plants. | While Catalent’s Bloomington, Indiana, site is no stranger to FDA reprimands, its latest write-up is notable given that the site forms part of the $16.5 billion deal Novo Holdings struck to acquire Catalent earlier this week.

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Brainomix’s AI-enabled stroke software endorsed by NICE

PharmaTimes

The HTA reported that Brainomix 360 improved access to treatment for stroke patients

Patients 107

More Trending

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AstraZeneca to boost cell therapy operations with $300m manufacturing investment

European Pharmaceutical Review

AstraZeneca has announced a $300 million investment in a US-based manufacturing facility in Rockville, Maryland, which will focus initially on T-cell therapies for oncology indications. The site will launch the company’ s cell therapy platforms in the US for critical cancer trials and future commercial supply. The site may widen its focus to support other disease areas, according to AstraZeneca.

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Eli Lilly’s Verzenio fails prostate cancer test as possible Novartis showdown nears

Fierce Pharma

Despite reaching new heights in breast cancer, Eli Lilly’s Verzenio has been sent packing in prostate cancer. | Despite reaching new heights in breast cancer, Eli Lilly’s Verzenio has been sent packing in prostate cancer. Meanwhile, the Indianapolis pharma has another phase 3 prostate cancer program in the works.

Pharma 200
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Gilead Sciences posts $5.61bn net income in FY 2023

Pharmaceutical Technology

Gilead Sciences has announced a 22.9% increase in net income of $5.61bn for FY23 as against $4.56bn in FY22.

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Amgen makes progress with its Horizon prize Tepezza, but there's much work left to do

Fierce Pharma

After Amgen completed its $27.8 billion buyout of Horizon Therapeutics in October, executives at the California biotech made it a priority to right the course of thyroid eye disease treatment Tepez | After Amgen completed its $27.8 billion buyout of Horizon Therapeutics in October, executives at the California biotech made it a priority to right the course of thyroid eye disease treatment Tepezza—an instant blockbuster that saw a perplexing slide in just its third full year on the market.

Sales 197
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AI Strategies for Sales Managers: How to Cut Down on Tedious Admin Work

What if you could help your sellers stop wasting 72% of their day on non-selling activities and focus on bringing in revenue? Incorporating AI in your enablement workflows can help you cut down on busy work, get projects done faster, and let your team (and you!) focus on making a bigger impact. We put together this guide to show you how to use AI to cut time and costs for projects, including collateral creation, development of training videos, and automating tedious processes.

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Jazz buys KRAS inhibitors from Redx in $880m deal

pharmaphorum

Jazz Pharmaceuticals has agreed another pipeline-building deal, this time paying $10 million upfront for rights to a KRAS inhibitor programme from UK biotech Redx Pharma, continuing a move into targeted cancer therapies. Under the terms of the deal, Jazz will acquire Redx’s KRAS inhibitor programme outright, including multiple preclinical-stage drug candidates, and will take responsibility for ushering the most promising compounds through clinical trials and onto the market.

Pharma 97
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Kyowa Kirin pays $100M to partner with BridgeBio on potential dwarfism drug

Fierce Pharma

With an upfront payment of $100 million, Kyowa Kirin has bought into a partnership with BridgeBio to develop and commercialize infigratinib in Japan.

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How will automation shape deviation management in continuous bioprocessing?

European Pharmaceutical Review

A paper published in Biotechnology Progress has explored real-time deviation management for integrated continuous bioprocesses and highlighted the role of automation. The discussion was based on a case study produced by the National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL). Specifically, the case study discussed a control strategy in the context of integrated continuous bioprocesses ( ICB ) for monoclonal antibodies (mAbs).

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AstraZeneca invests $300m to build new facility in US

Pharmaceutical Technology

AstraZeneca is investing $300m in a facility in Rockville, US - a significant step in launching its cell therapy platforms in the country.

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Foundational ABM Building Blocks

Account-based marketing (ABM) is a key strategy for driving sustainable growth. Today, many B2B companies use ABM teams or technologies to make sales. But getting a program off the ground successfully doesn’t have to be a daunting task. Watch this webinar with Rachael Foster, Director of Account-Based Experience at ZoomInfo, and Dan Dolph, Manager of Account-Based Experience at ZoomInfo.

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Safety Risks and FDA Hold Lead Gilead to Stop Work on Drug in Blood Cancers

MedCity News

Gilead Sciences said an independent review of interim Phase 3 data found the immunotherapy, magrolimab, led to a higher risk of death. Though Gilead is discontinuing further development of the drug in blood cancers, a review is ongoing in solid tumors.

Safety 95
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ALTURiX acquires exclusive UK rights to three new products

PharmaTimes

The new products are in the areas of gastrointestinal and respiratory medicines

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NHS England pushes BRCA testing for Jewish community

pharmaphorum

Jewish people in England are being asked to have gene testing for BRCA mutations that elevate their risk of breast cancer

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Empowering Patient Healthcare Decision-Making: How Resource Sheets Support Patient Understanding of Clinical Trial Data

MedCity News

Providing patients with comprehensive patient resource sheets on clinical trials can alleviate worry, support dialog with family members and clinical care providers and empower informed decision-making.

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How to Prove Marketing Value: Demonstrate Content ROI and Contribution to Sales

Every marketer knows how important it is to prove their efforts drive sales opportunities, but that’s easier said than done. When problems like sales and marketing misalignment, lack of data, and wasted efforts persist, marketers can’t measure, prove, or increase their impact on revenue at a time when demonstrating marketing value is critical. Using analyst and expert data, this guide to marketing impact and content attribution explains: How B2B buyers use content The most common types of conten

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GSK backs up its Blenrep rehab bid with survival data

pharmaphorum

GSK has revealed the data it hopes will allow a return to the US market for Blenrep, which was the first BCMA-targeting drug to launch there but was withdrawn from sale after it failed a confirmatory trial.

Sales 88
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Believing Amazon’s Job Cuts Signal an Exit From Healthcare Would Be ‘Overly Simplistic,’ Expert Says

MedCity News

Amazon has eliminated “a few hundred” jobs across Amazon Pharmacy and One Medical, the company confirmed to MedCity News Wednesday. While some may believe this could lead to Amazon leaving healthcare, one industry expert said that would be an “overly simplistic” takeaway.

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Could Novo-Catalent deal face antitrust hurdles?

pharmaphorum

Eli Lilly has called on financial regulators to look into the antitrust implications of Novo Holdings purchase of Catalent and the sale of three manufacturing facilities to Novo Nordisk.

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Avadomide hydrochloride by Bristol-Myers Squibb for Follicular Lymphoma: Likelihood of Approval

Pharmaceutical Technology

Avadomide hydrochloride is under clinical development by Bristol-Myers Squibb and currently in Phase I for Follicular Lymphoma.

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AI in Sales: How AI is Transforming Go-to-Market

How will generative AI transform sales? It’s a question that promises to drive billions of dollars in revenue opportunities over the next five to 10 years. And if you’re not leveraging AI solutions in your go-to-market motions, you’re already behind. In this eBook, we’ll cover: How today’s top sales leaders are incorporating AI into their go-to-market motions.

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Pharma has a misinformation problem — and execs could be on the hook

PharmaVoice

Investment heavyweights BlackRock and Glass Lewis want compensation clawbacks on execs who don’t protect a company’s reputation.

Pharma 64
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Ligelizumab by Novartis for Food Allergy: Likelihood of Approval

Pharmaceutical Technology

Ligelizumab is under clinical development by Novartis and currently in Phase III for Food Allergy.

Food 75
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Real Chemistry grows in med comms with Avant buy

pharmaphorum

Life sciences communications agency Real Chemistry has more than doubled its medical team through the acquisition of Avant Healthcare. The takeover – which was completed earlier this month for an undisclosed sum – will bolster Real Chemistry’s medical education, medical affairs, and healthcare provider (HCP) communications capabilities, said the company in a statement.

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(Sacubitril + valsartan) by Novartis for Hypertrophic Cardiomyopathy: Likelihood of Approval

Pharmaceutical Technology

(Sacubitril + valsartan) is under clinical development by Novartis and currently in Phase II for Hypertrophic Cardiomyopathy.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Safety Analysis Shows PPSV23 Is Not Associated With Higher Risk of Serious Outcomes

Pharmacy Times

The 23-valent pneumococcal polysaccharide vaccine was most likely associated with a higher risk of immunological events for those who were immunocompromised, but the events were low.

Safety 55
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Enfortumab vedotin by Astellas Pharma for Esophageal Squamous Cell Carcinoma (ESCC): Likelihood of Approval

Pharmaceutical Technology

Enfortumab vedotin is under clinical development by Astellas Pharma and currently in Phase II for Esophageal Squamous Cell Carcinoma (ESCC).

Pharma 71
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Cardiovascular Mortality Rates Increased From 2020 to 2022, Correlating With Pandemic

Pharmacy Times

Investigators also found that the mortality rates for cardiovascular disease from 2020 to 2022 reversed the improvements of reduced mortalities in the preceding decades.

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Irinotecan hydrochloride by Ipsen for Neuroendocrine Carcinoma: Likelihood of Approval

Pharmaceutical Technology

Irinotecan hydrochloride is under clinical development by Ipsen and currently in Phase II for Neuroendocrine Carcinoma.

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Marketing Operations Efficiency: The Essential Checklist

As marketing becomes more tech-driven, the role of marketing operations (MOps) is getting more complex. Today, the discipline is increasingly interwoven with other vital go-to-market motions — including sales and customer support — and is responsible for all business elements associated with marketing, including the tech stack. In this eBook, we’ll show you how marketing operations can create efficiencies in your tech stack, reporting, and budget that will not just improve internal processes, bu