Tue.May 14, 2024

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With 4-year data, Novo bolsters star power of obesity blockbuster Wegovy

Fierce Pharma

With new four-year data in hand, Novo Nordisk can make a case for its popular obesity med Wegovy to be used as a long-term treatment. | An analysis unveiled at the European Congress on Obesity showed that Wegovy patients lost 10% of their weight, on average, over a 4-year span.

Patients 284
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SmarterDx Rakes In $50M For Its AI That Helps Hospitals Capture More Revenue

MedCity News

SmarterDx — an AI startup that provides clinical review and quality audits for medical claims — closed a $50 million Series B funding round, bringing its total funding to date to $71 million. The post SmarterDx Rakes In $50M For Its AI That Helps Hospitals Capture More Revenue appeared first on MedCity News.

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Lonza, busy with capacity upgrades and exec turnover, hints at CDMO industry rebound

Fierce Pharma

A tough biotech funding environment and a downturn in COVID-related contracts has weighed heavily on CDMOs of all stripes in recent years. | With a new CEO waiting in the wings, Swiss manufacturing juggernaut Lonza is attempting to reassure the market that a CDMO industry stabilization is playing out.

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Right-to-Repair Laws Could Threaten Healthcare Safety

MedCity News

Healthcare devices must be exempted from general right to repair legislation. The post Right-to-Repair Laws Could Threaten Healthcare Safety appeared first on MedCity News.

Safety 121
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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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Bayer slashed 1,500 roles in Q1 as simpler organization takes shape

Fierce Pharma

When Bayer unveiled a restructuring in January, the company didn’t provide specifics on the number of planned job cuts. | When Bayer unveiled a restructuring in January, the company didn't provide specifics on the number of planned job cuts. Now, the size of the initial round of cuts shows that CEO Bill Anderson means business.

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ICER raps conduct of Lykos’ psychedelic trial for PTSD

pharmaphorum

The Institute for Clinical and Economic Review (ICER) typically focuses on the cost-effectiveness of new therapies, but in an unusual move has sharply criticised the design and conduct of clinical trials of Lykos Therapeutics psychedelic therapy for post-traumatic stress disorder (PTSD).

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Quantum Health Launches New Pharmacy Navigation Solution for Employers

MedCity News

Quantum Health launched its Premier Pharmacy navigation solution on Tuesday. The solution helps members find safe and effective therapeutic alternatives to expensive medications. The post Quantum Health Launches New Pharmacy Navigation Solution for Employers appeared first on MedCity News.

Medical 104
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After filing hitch, Eisai and Biogen begin rolling FDA submission for subcutaneous Leqembi

Fierce Pharma

After suffering a setback with U.S. regulators last month, Eisai and Biogen’s effort to deploy a more convenient version of their Alzheimer’s disease drug Leqembi appears to be back on track. | Late Tuesday, Biogen and Eisai said they kicked off a rolling FDA submission for the subcutaneous version of Leqembi—which is currently infused—after winning a fast track tag from the agency.

FDA 233
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Bayer cutbacks start to be felt with 1,500 jobs shed in Q1

pharmaphorum

Bayer's first-quarter results update shows its headcount has shrunk by around 1,500 since the start of the year, suggesting promised job cuts are starting to take hold

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Unlike Regeneron, Bayer doesn't feel as much of a pinch from Roche's Vabysmo

Fierce Pharma

Roche’s Vabysmo has taken a chunk of the market from Regeneron and Bayer’s Eylea. But Bayer hasn’t taken quite the same hit as its U.S. partner.

Marketing 219
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Sanofi adds to biomanufacturing investment in France

European Pharmaceutical Review

Using an investment of over €1 billion, Sanofi plans to generate new bioproduction capacity at three sites in France, focusing on biologic medicines. The sites are in Vitry-sur-Seine (Val de Marne), Le Trait (Seine-Maritime) and Lyon Gerland (Rhône). This cash injection will create more than 500 jobs and “significantly strengthen” France’s present and future ability to control the full production process of essential medicines, the company stated.

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Sales Negotiation Skills That Deliver Success

Integrity Solutions

For many in sales, negotiation is one of the most challenging aspects of the job. More often than not, these salespeople approach negotiation as a win-or-lose endurance game, a contentious battle that pits two opposing sides against each other. “Winning” means convincing the customer to accept your point of view—even if the outcome isn’t necessarily in the customer’s best interest.

Sales 96
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Takeda agrees to develop active immunotherapy for Alzheimer’s

European Pharmaceutical Review

Takeda and AC Immune SA have agreed a global option and license agreement for a potential first-in-class Abeta-targeting active immunotherapy for Alzheimer’s. AC Immune’s related immunotherapies targeting Abeta are part of the deal, including the Alzheimer’s treatment ACI-24.060. According to Takeda, based on blinded data, immunogenicity of this immunotherapy is “very encouraging with clear evidence of anti-Abeta antibody responses”.

Safety 97
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Cytokinetics prepares to take on BMS’ Camzyos in HCM

pharmaphorum

Cytokinetics has revealed the results from a phase 3 trial of its hypertrophic cardiomyopathy (HCM) drug aficamten that it hopes will allow it to compete with Bristol-Myers Squibb’s first-to-market Camzyos.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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Big Pharma’s most improved drugs: a new generation of blockbusters

PharmaVoice

The old guard of pharma bestsellers is seeing more competition, but newer drugs demonstrating sales and revenue growth can build up the coffers in years to come.

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AbbVie makes psychedelic play with $2bn Gilgamesh collaboration

Pharmaceutical Technology

The two companies will develop neuroplastogens for psychiatric disorders as psychedelic market activity ramps up.

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Study reveals heart failure device could monitor patients and prevent hospitalisation

PharmaTimes

Heart failure is a cardiovascular disease that affects more than 64 million people worldwide

Patients 103
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AbbVie Expands Psychiatric Drug Prospects, Inking R&D Pact With Neuroscience Startup

MedCity News

AbbVie’s alliance with Gilgamesh Pharmaceuticals is pursuing next-generation psychiatric medications. The companies aim to bring patients drugs that offer the benefit of psychedelics but with a better side effect profile. The post AbbVie Expands Psychiatric Drug Prospects, Inking R&D Pact With Neuroscience Startup appeared first on MedCity News.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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UKHSA and ICL confirm variant which plays key role in global surge of Strep A infections

PharmaTimes

More than 3,000 people in England were affected by Strep A between September 2022 and May 2023

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Cresset to Open New Headquarters in Bangalore, India

PharmaTech

The drug discovery company intends for this new site to increase its reach in the region, supporting growing demands from its Asia-Pacific consumers.

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Semaglutide heart benefits may go beyond weight loss

pharmaphorum

New data suggests that the benefits of Novo Nordisk’s GLP-1 agonist semaglutide in preventing cardiovascular diseases may not simply be a result of weight loss.

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Pharma Pulse 5/14/24: The Impact of Medicare Advantage Employer Group Waiver Plans, The Need for Stepped-Up Patient Support & more

Pharmaceutical Commerce

The latest news for pharma industry insiders.

Pharma 105
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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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Unveiling the Power of Targeted Marketing with Dentist Directories

Scott’s Directories

Imagine having a treasure trove of information at your fingertips, a comprehensive database filled with valuable insights about dentists across Canada. This includes a dedicated dentist directory in Ontario , providing a wealth of details to streamline your marketing efforts and reach the perfect audience. As one of the leading names in dentist database solutions, MD Select understands the challenges businesses face.

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The Role of VR in Medical Device Marketing

Infuse Medical

Definition of VR Virtual Reality (VR) refers to a computer-generated simulation of an environment or experience that immerses users in a three-dimensional, interactive world. Through the use of specialized hardware, such as VR headsets or goggles, and software applications, users can perceive and interact with this digital environment as if they were physically present within it.

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9 Ways to Get Qualified Manufacturing Sales Leads

Spotio

You’re here because you want more manufacturing sales leads—and you’re not alone. Recent research shows that 63% of manufacturers consider marketing a “high priority” It makes sense: good marketing produces quality leads, who can then be sold to by sales teams. The question is, how do you market your manufacturing business effectively?

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Expert Perspectives on Boosting Sales Growth with AI in Life Sciences

Quantified

How fast – and how far – is the pharmaceutical industry going in adopting AI? To get a pulse on that question, we had a series of conversations with experts from Viatris, the National Institute for Health and Care Excellence at Health Innovation Manchester, Asklepios BioPharmaceutical, Roche, Harvard Business School, Ipsen, and EPAM Systems.

Sales 52
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Healthcare Marketing Strategies for Reaching Diverse Audiences

PharmExec

Amanda Powers-Han, Chief Marketing Officer, Greater Than One, and Pharmaceutical Executive Editorial Advisory Board member, discusses how improved DE&I in healthcare marketing strategies can not only reach diverse audiences more effectively but also contribute to improved patient care outcomes, challenges faced in crafting culturally sensitive messages, and much more.

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What a string of semaglutide biosimilars could mean for Mainland China

Clarivate

GLP-1 (Glucagon like peptide 1) receptor agonists, a commonly prescribed drug class in the treatment of type 2 diabetes (T2D), successfully mimic a natural gut hormone, increasing production of insulin in the human body. While initially developed to help regulate blood sugar levels, they have also been found to promote appetite suppression, leading to weight loss in patients.

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Cencora VP of Emerging Therapies Talks Innovative Order-to-Cash Solutions for Cell and Gene Therapies

PharmExec

In an interview with Pharm Exec Associate Editor Don Tracy, Melissa Melissa Lattanzi, VP, Emerging Therapies, Cencora discusses the process of coming up with can innovative order-to-cash solutions help to maximize market reach.

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Walden Biosciences teams up with Primula for kidney disease study 

Pharmaceutical Technology

Walden reported positive topline data from a Phase I clinical trial of its lead candidate WAL0921, a humanised mAb to treat kidney disease.

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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.