Tue.Dec 12, 2023

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Europe names hundreds of critical medicines in quest to counter drug shortages

Fierce Pharma

Over the past several years, drug shortages have vexed doctors and patients on both sides of the Atlantic, prompting lawmakers and government agencies to take action in both Europe and the U.S. | Tuesday, the European Medicines Agency laid out a list of more than 300 critical generic drugs that could fall prey to future shortages. Inclusion in the list doesn’t mean a particular drug is likely to experience a shortage anytime soon, the EMA said.

Medicine 358
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NK cell immunotherapy: what’s next in clinical development?

European Pharmaceutical Review

Yannis Morel, Executive Vice President of product portfolio strategy and business development of Innate Pharma SA, offers insight on engineering antibodies to develop antibody-based NK cell therapeutics. He discusses why NK cell therapy’s ability to generate ‘synthetic immunity’ in the body means this modality holds potential as an anti-cancer treatment.

Pharma 124
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Pfizer reveals reorganization, executive departure as it gets ready to close $43B Seagen buyout

Fierce Pharma

To complete its acquisition of Seagen, what did Pfizer need to do to satisfy antitrust concerns of the Federal Trade Commission? | By agreeing to donate royalties on its U.S. sales of bladder cancer drug Bavencio, Pfizer has received the go-ahead to finalize its $43 billion buyout of Seagen, the company said on Tuesday. Pfizer expects to close the merger on Thursday.

Sales 310
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Sanofi Abandons Deal for Rare Disease Drug Amid FTC’s Monopoly Concerns

MedCity News

Sanofi, which markets the two primary treatments for Pompe disease, was trying to add a third one by licensing rights to a Maze Therapeutics drug candidate with a different therapeutic approach. A Federal Trade Commission complaint alleges the deal amounts to a monopoly player taking out its competition.

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AI Strategies for Sales Managers: How to Cut Down on Tedious Admin Work

What if you could help your sellers stop wasting 72% of their day on non-selling activities and focus on bringing in revenue? Incorporating AI in your enablement workflows can help you cut down on busy work, get projects done faster, and let your team (and you!) focus on making a bigger impact. We put together this guide to show you how to use AI to cut time and costs for projects, including collateral creation, development of training videos, and automating tedious processes.

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Ferring trims US workforce by 134 with layoffs in New Jersey, Minnesota

Fierce Pharma

As waves of layoffs continue to hit the biopharma industry, Ferring Pharmaceuticals is trimming its headcount by 134 across its two U.S. locations. | The drugmaker will lay off 79 at its New Jersey headquarters and 55 at its microbiome subsidiary Rebiotix in Minnesota as a result of a "revised business strategy.

Biopharma 260
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Bipartisan Price Transparency Bill Passes in House

MedCity News

The Lower Costs, More Transparency Act has passed in the House with bipartisan support. The action is being applauded from several advocacy organizations.

More Trending

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AI Enhances Workflows; It Doesn’t Replace Physicians.

MedCity News

The integration of AI into cardiology workflows can help triage care automatically, ensuring the right physicians weigh in on patient data at the right time which may potentially improve clinical outcomes for all patients in need.

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National Resilience lines up 440 new jobs at former AstraZeneca plant in Ohio

Fierce Pharma

After multiple expansion forays overseas this year, biomanufacturing outfit National Resilience is returning to its American roots with plans to beef up production and add hundreds of new jobs at a | Resilience is expanding operations at the West Chester, Ohio, facility it bought from AstraZeneca in January, the technology-focused contract manufacturer said Monday.

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Americans’ Healthcare Costs Are Rising With the Pace of Inflation, Report Says

MedCity News

During the first three quarters of 2023, the prices for CMS’ 500 shoppable services increased by 2.0%, according to a new report. This figure is in alignment with the 1.9% U.S. inflation measured by the Personal Consumption Expenditures Price Index and below the overall U.S. inflation rate measured by the Consumer Price Index.

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Troubled Evofem, marketer of contraceptive gel Phexxi, sells itself to Aditxt in $100M deal

Fierce Pharma

Evofem has struggled to gain commercial traction with Phexxi. Now, it's selling itself after shares crashed dramatically over the last few years.

Marketing 254
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Construction starts on $400m biosimilars production centre in Slovenia

European Pharmaceutical Review

The first stage of construction has officially begun on Lek Pharmaceuticals’ new biologics and biosimilars production centre in Lendava, north eastern Slovenia. Representing the largest foreign direct investment in Slovenia, the launch of the $400 million centre was attended by key Slovenian representatives, including the Prime Minister, Robert Golob.

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ASH: J&J, Sanofi square off in newly diagnosed multiple myeloma, with one med showing 'unprecedented' efficacy

Fierce Pharma

Another data face-off between the two anti-CD38 multiple myeloma drugs—Johnson & Johnson’s Darzalex and Sanofi’s Sarclisa—took place at the 65th American Society of Hematology meeting. | Another data face-off between the two anti-CD38 multiple myeloma drugs—J&J's Darzalex and Sanofi's Sarclisa—took place at the ASH conference. Both regimens showed strong efficacy in newly diagnosed patients, but only one result is considered practice-changing right now.

Patients 215
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FDA approves first cell-based gene therapies for sickle cell disease

European Pharmaceutical Review

The US Food and Drug Administration (FDA) has approved two landmark cell-based gene therapies for treatment of inherited blood disorder sickle cell disease. Casgevy (exagamglogene autotemcel) a cell-based gene therapy, is approved for the treatment of sickle cell disease in patients 12 years of age and older with recurrent vaso-occlusive crises (VOCs).

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ASH: After Imbruvica's stumble in mantle cell lymphoma, AbbVie and J&J eye possible combo comeback

Fierce Pharma

With the initial shock of AbbVie and Johnson & Johnson's disease-specific approval pull for Imbruvica now fading into the rearview, the partners are making the case for the BTK inhibitor to sta | With the initial shock of AbbVie and Johnson & Johnson's disease-specific approval pull for Imbruvica now fading into the rearview, the partners are making the case for the BTK inhibitor to stage a comeback in mantle cell lymphoma.

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How to Prove Marketing Value: Demonstrate Content ROI and Contribution to Sales

Every marketer knows how important it is to prove their efforts drive sales opportunities, but that’s easier said than done. When problems like sales and marketing misalignment, lack of data, and wasted efforts persist, marketers can’t measure, prove, or increase their impact on revenue at a time when demonstrating marketing value is critical. Using analyst and expert data, this guide to marketing impact and content attribution explains: How B2B buyers use content The most common types of conten

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Remote Reliance: The Rise of Oncology Home Care

PharmExec

While hurdles remain, home healthcare could deliver better patient-centered cancer care—providing improved outcomes, enhanced quality of life, and reduced strain on resources.

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MedCity Pivot: How a Health Center Serving Low Income Patients Engaged Them In Their Own Health

MedCity News

In the last episode of the year, Wrobel, CEO of an Indiana-based federally qualified health center, describes how a survey helped her and her community workers understand exactly how confident her patients are in managing their own care and the best way to help them with the ultimate goal of improving overall health equity.

Patients 108
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Clearing Away the Clutter: Implementing Value-Based Contracting in Pharma

PharmExec

Experts gauge whether the needle is finally moving on the effective structuring of outcomes centered payment agreements—from operational, technology, and acceptance standpoints.

Pharma 103
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Zocdoc CEO Predicts 5 Ways Patient Behavior Will Change in 2024

MedCity News

Zocdoc Founder and CEO Oliver Kharraz gave five predictions about how patient preferences will evolve in 2024. Some of them include Americans increasingly seeking cash-pay care options and an uptick in patients seeking mental health appointments before and after the presidential election.

Patients 108
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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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Trade & Channel Strategies 2023: An Interview with Cheryl Allen of Curatio Scientia

Pharmaceutical Commerce

Founding Partner of Curatio Scientia speaks on her upcoming panel at Trade & Channel Strategies 2023.

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AstraZeneca’s Icosavax M&A Deal Helps It Stand Out in Multivalent Vaccines Chase

MedCity News

AstraZeneca is acquiring Icosavax, which has technology well-suited for multivalent vaccines. Icosavax’s pipeline includes a Phase 3-ready program that protects against two pathogens that cause severe respiratory infections in older adults.

Biopharma 107
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Babies born early have an increased risk of developmental disorders

PharmaTimes

Around 240 million children worldwide are living with these types of disorders - News - PharmaTimes

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Talkspace, Evernow Partner To Advance Mental Health, Menopause Care

MedCity News

Talkspace is offering free self-guided mental health content to some female Evernow customers over the age of 40, while Evernow is offering discounted menopause care to Talkspace patients.

Patients 106
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Increase Revenue With Better, Faster Sales Onboarding

Quotas need to be hit. Revenue goals need to be met. This reality makes shortening sales onboarding time a top priority. Organizations with a standard onboarding process boost employee retention by 58% and increase productivity by 50%. Unfortunately, many companies struggle with inefficient processes that lead to high turnover and missed revenue opportunities.

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Trade & Channel Strategies 2023: An Interview with Bayer's Spencer Miller

Pharmaceutical Commerce

Bayer executive talks Enable Holistic Hub and Provider Services panel.

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Navigating a Successful M&A Integration Process

MedCity News

Integrations are incredibly destabilizing and stressful for impacted employees, as well as for those who “survive.” Organizations that are worth acquiring are successful and attractive because they are comprised of smart, talented people who have created that success.

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BMS bolts on SystImmune bispecific ADC in $8.4bn deal

pharmaphorum

BMS bolts on SystImmune bispecific ADC in $8.4bn deal Phil.

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How Organizations Can Lower Their Risks of Diversion

MedCity News

While there will never be a perfect solution to preventing drug diversion 100% of the time, leveraging the right people, processes and technology is our best chance of keeping patients safe.

Patients 101
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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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Innovating IP management: Making FoundationIP even better

Clarivate

At Clarivate, we understand that IP professionals are under constant pressure to deliver more value to clients and stakeholders with greater speed and efficiency. That’s why we continue to invest in advanced tools that help IP attorneys, paralegals and legal operations teams work smarter, not harder. Case in point: FoundationIP , the first SaaS-based IP management solution, purpose built to increase IP team efficiency by leveraging automation and best in class country rules.

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Nitrosamines analysis with LC/MS-MS

European Pharmaceutical Review

In recent years, nitrosamines have been detected in various medicines, leading to voluntary product recalls from the market. Nitrosamines analysis is, thus, key to ensuring safety and quality in the pharmaceutical industry. Global regulatory bodies now require pharmaceutical manufacturers to control and strive to mitigate the presence of N- nitrosamines in their products.

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Digitised pathology resource will speed HIV cancer R&D

pharmaphorum

Digitised pathology resource will speed HIV cancer R&D Phil.

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New study finds heathy cells ‘push’ cancer cells to resist treatment

PharmaTimes

Slow-growing cancer cells become more resistant to chemotherapy treatment - News - PharmaTimes

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Using Generative AI in Sales: Pros, Cons, and Considerations According to Sellers

Are your sellers unsure about using AI in their day-to-day workflows? Or are they eager to try but uncertain where to start? They might be asking: Which tasks are best suited for AI? How will using AI affect my relationship with my customers? With so many tools available, which ones are the most useful to me? To help answer these and other common questions about using AI during the sales cycle, we surveyed B2B sellers who were early adopters to get their insight and advice about how to use gen A