Mon.Nov 06, 2023

article thumbnail

NICE's Trikafta snub could portend another pricing standoff between Vertex and UK officials

Fierce Pharma

History may repeat for Vertex Pharmaceuticals in the U.K., where a new decision by the country’s cost-effectiveness gatekeeper threatens to spark another dispute over the cost of lifesaving cystic | Last week, the U.K.'s National Institute for Health and Care Excellence unveiled draft guidance that acknowledged the effectiveness of Vertex’s cystic fibrosis drugs Trikafta, Symkevi and Orkambi.

Medicine 287
article thumbnail

Why GLP-1s Alone Cannot Solve the Obesity Crisis

MedCity News

People with obesity should be offered a range of suitable treatments as well: behavioral, nutrition, exercise, medication and surgery, through a coordinated and holistic approach under one roof, with a care coordinator. Like cancer, obesity is a heterogeneous disease and recommendations and responses to all treatment modalities will be heterogeneous as well.

Medical 115
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

Krystal's topical gene therapy gains steam, prompting analyst group to boost sales projection

Fierce Pharma

At the start of its first-ever conference call to present its quarterly numbers, Krystal Biotech CEO Krish Krishnan was quick to point out that the company’s positive earnings for the third quarter | Krystal Biotech's launch of Vyjuvek, the world's first topical gene therapy, has been so promising that analysts with Evercore ISI increased their 2024 sales projection to $273 million.

Sales 276
article thumbnail

Celldex Drug Flashes Potential to Compete With, Maybe Beat Rival Big Pharma Meds

MedCity News

Celldex drug barzolvolimab has mid-stage results in a chronic inflammatory skin disease that top those of an approved Genentech drug and two experimental Novartis therapies. The biotech is preparing to advance its drug to Phase 3 testing in 2024.

Pharma 115
article thumbnail

AI Strategies for Sales Managers: How to Cut Down on Tedious Admin Work

What if you could help your sellers stop wasting 72% of their day on non-selling activities and focus on bringing in revenue? Incorporating AI in your enablement workflows can help you cut down on busy work, get projects done faster, and let your team (and you!) focus on making a bigger impact. We put together this guide to show you how to use AI to cut time and costs for projects, including collateral creation, development of training videos, and automating tedious processes.

article thumbnail

As Vertex preps for exa-cel launch, exec touts 'very large' opportunity but tempers early expectations

Fierce Pharma

As Vertex preps for exa-cel launch, exec touts 'very large' opportunity but tempers early expectations zbecker Mon, 11/06/2023 - 20:59

294
294
article thumbnail

Global cell line development to surge in next decade

European Pharmaceutical Review

The global cell line development industry is expected to value $4,674.8 million by 2033, according to a report by Future Market Insights. Total cell line product sales are expected to reach $3,124.4 million in 2023, with a predicted compound annual growth rate (CAGR) of 4.1 percent through the next decade. Advancements in biotechnology, pharmaceutical research, and biomanufacturing processes are key factors in driving the market, the author acknowledged.

Marketing 105

More Trending

article thumbnail

Urban Institute: 400,000 Veterans Expected to be Uninsured in 2024

MedCity News

About half (47%) of nonelderly uninsured veterans will be eligible for Medicaid or subsidies through the ACA Marketplace in 2024, according to a new report from the Urban Institute.

111
111
article thumbnail

BioNTech cuts 2023 revenue guidance by 20%, but touts its financial position

Fierce Pharma

Following suit with other companies that produce COVID-19 vaccines, BioNTech has discovered demand for its Pfizer-partnered, omicron-adapted shot has not met expectations this fall and has had to a | BioNTech has slashed its estimate of 2023 revenue by 20%, now expecting it to reach 4 billion euros ($4.3 billion) versus its previous estimate of 5 billion euros ($5.4 billion).

Sales 240
article thumbnail

Report: Percentage of Workers Eligible for Employment-Based Coverage Increased 5% Since 2014

MedCity News

It was expected that the Affordable Care Act would lead to many employers dropping health benefits, but that did not happen, a new report from the Employee Benefit Research Institute found.

Leads 110
article thumbnail

Astellas touts 2-year results for $4.9B GA drug Izervay as it amps up Apellis rivalry

Fierce Pharma

When Astellas ponied up $4.9 billion for Iveric Bio earlier this year, the company had identified the promise of Iveric's geographic atrophy candidate, now approved as Izervay, as a future revenue | Astellas is counting on Izervay to deliver gains in a heated GA market clash against rival Apellis. Now, 2-year data show the drug's effects increase over time.

Marketing 167
article thumbnail

From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

article thumbnail

AAO 2023: intravitreal treatment shows benefit in geographic atrophy

European Pharmaceutical Review

IZERVAY ( avacincaptad pegol intravitreal solution) induced a year-over-year reductions in the rate of geographic atrophy lesion growth in patients with geographic atrophy secondary to age-related macular degeneration (AMD) in a Phase III trial, Astellas Pharma has announced. The findings presented at the American Academy of Ophthalmology (AAO) 2023 Annual Meeting, revealed that the treatment continued to reduce the rate of geographic atrophy lesion growth for both every month and every-other-mo

article thumbnail

Axsome expands sales force to support launch of fast-growing depression med Auvelity

Fierce Pharma

With revenue on the rise for its fast-working depression med Auvelity, Axsome Therapeutics is in the process of boosting its sales force with nearly 100 new hires. | The company plans to expand its Auvelity sales force from 162 to 260 reps by next quarter in an effort to reach some 18,000 new prescribers.

Sales 167
article thumbnail

BMS Pays $100M for Next-Gen Orum Therapeutics ADC for Blood Cancers

MedCity News

Bristol Myers Squibb is expanding its scope in cancer by acquiring rights to a Phase 1-ready Orum Therapeutics program that brings a new twist to antibody drug conjugates. The deal is the latest business development move in the hot field of ADCs.

Biopharma 109
article thumbnail

Increasing Solubility with Zerion Pharma at CPHI Barcelona

PharmaTech

Pharmaceutical Technology Europe® spoke with Ole Wiborg from Zerion Pharma, a Danish pharmaceutical development company, at the inaugural Start-Up Market on the show floor at CPHI Barcelona 2023.

Pharma 98
article thumbnail

How to Prove Marketing Value: Demonstrate Content ROI and Contribution to Sales

Every marketer knows how important it is to prove their efforts drive sales opportunities, but that’s easier said than done. When problems like sales and marketing misalignment, lack of data, and wasted efforts persist, marketers can’t measure, prove, or increase their impact on revenue at a time when demonstrating marketing value is critical. Using analyst and expert data, this guide to marketing impact and content attribution explains: How B2B buyers use content The most common types of conten

article thumbnail

MHRA authorises new treatment for rare lung cancer

European Pharmaceutical Review

A new medicine to treat adults with non-small cell lung cancer (NSCLC) with a rare mutation called KRAS G12C has been authorised by the UK Medicines and Healthcare products Regulatory Agency (MHRA). According to the MHRA, Mirati Therapeutics B.V.’s Krazati ® (adagrasib) can be used in this indication in individuals who have an advanced form of the disease, or it has spread to other parts of the body.

article thumbnail

Drug Diversion in Healthcare is a National Problem, but Recent Survey Shows a Promising Path Forward

PharmExec

Healthcare organizations can lower their risk of drug diversion by strengthening staffing, employee training, and technology.

article thumbnail

Samay’s AI-assisted wearable technology accurately diagnoses COPD

PharmaTimes

The device successfully diagnosed COPD in patients with 90% accuracy - News - PharmaTimes

Patients 122
article thumbnail

INVEST Digital Health Pitch Perfect Spotlight: Hera Is Building a Better Way to Diagnose Endometriosis

MedCity News

Hera Biotech, a San Antonio-based startup developing a nonsurgical diagnostic test for endometriosis, won the Pitch Perfect contest at MedCity News’ INVEST Digital Health conference. The average diagnostic delay for the endometriosis is eight years, driven in large part by the fact that the only method currently used to diagnose the disease is a surgical procedure.

95
article thumbnail

Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

article thumbnail

The thorniest questions facing pharma, according to a leading bioethicist

PharmaVoice

Bioethics guru Arthur Caplan of NYU gives his outspoken and frank opinion on the industry’s minefield of ethical challenges.

Ethics 98
article thumbnail

RCM Staff Shortages Are Making It a Lot Harder for Providers to Get Paid

MedCity News

Discussions around healthcare’s workforce crisis usually center around providers’ lack of clinicians, but there’s a sweeping shortage of revenue cycle workers, too. In a new report, Experian Health surveyed 200 employees who are responsible for staffing the revenue cycle function at providers — every respondent said that staff shortages are having a significant negative impact on their organization’s ability to get paid for care and/or patient engagement.

article thumbnail

First high-resolution 3D image offers insight into heart and muscle health

PharmaTimes

The image helps researchers understand how heart muscles operate in disease - News - PharmaTimes

103
103
article thumbnail

A Look at Hachette v. Internet Archive

Copyright Clearance Center

The post A Look at Hachette v. Internet Archive appeared first on Copyright Clearance Center.

98
article thumbnail

Increase Revenue With Better, Faster Sales Onboarding

Quotas need to be hit. Revenue goals need to be met. This reality makes shortening sales onboarding time a top priority. Organizations with a standard onboarding process boost employee retention by 58% and increase productivity by 50%. Unfortunately, many companies struggle with inefficient processes that lead to high turnover and missed revenue opportunities.

article thumbnail

Cell & gene therapy: the leading companies in rAAV production technology revealed

Pharmaceutical Technology

GlobalData uncovers the leading innovators in rAAV production technology for the pharmaceutical industry.

Leads 89
article thumbnail

UK patient data project reaches one million volunteers

pharmaphorum

UK patient data project reaches one million volunteers Phil.

Patients 113
article thumbnail

Mirati wins conditional UK approval for Krazati in NSCLC

Pharmaceutical Technology

Krazati received conditional marketing authorisation as a second-line treatment of KRAS-G12C mutated locally advanced or metastatic NSCLC.

article thumbnail

Drug combos from AZ, Boehringer show promise in CKD

pharmaphorum

Drug combos from AZ, Boehringer show promise in CKD Phil.

112
112
article thumbnail

European Clinical Supply Planning: Balancing Cost, Flexibility and Time

article thumbnail

Skyrocket Your Sales: Innovative Strategies to Crush Your Targets

Contrarian Sales Techniques

In the last quarter alone, businesses that revamped their sales strategies saw a staggering 34% increase in revenue, outpacing competitors who adhered to traditional methods. This statistic isn't just a number—it's a testament to the transformative power of innovative sales approaches in today's market. In an era where consumer behaviors shift as rapidly as the technologies they use, the ability to adapt sales tactics is not just advantageous—it's essential.

Sales 52
article thumbnail

Bayer doubles down on Factor XIa with new phase 3 trial

pharmaphorum

Bayer doubles down on Factor XIa with new phase 3 trial Phil.

99
article thumbnail

Distinguishing E&L Testing for Combination Products (AAPS PharmSci 360)

PharmaTech

Dujuan Lu, PhD, global leader—E&L, SGS Health Sciences, talks about the differences in designing E&L testing for combination products vs. conventional pharmaceuticals.

article thumbnail

Trinity Capital Inc. Provides $25 Million Growth Capital to Neuros Medical, Inc.

Legacy MEDSearch

Trinity Capital Inc. (NASDAQ: TRIN ) (“Trinity”), a leading provider of diversified financial solutions to growth-stage companies, today announced the commitment of $25 million in growth capital to Neuros Medical, Inc., a bioelectric technology company focused on alleviating chronic post-amputation pain and restoring quality of life. Neuros Medical’s Altius System incorporates the company’s patented platform technology, On-Demand Bioelectric Nerve Block, which patients

Medical 52
article thumbnail

Using Generative AI in Sales: Pros, Cons, and Considerations According to Sellers

Are your sellers unsure about using AI in their day-to-day workflows? Or are they eager to try but uncertain where to start? They might be asking: Which tasks are best suited for AI? How will using AI affect my relationship with my customers? With so many tools available, which ones are the most useful to me? To help answer these and other common questions about using AI during the sales cycle, we surveyed B2B sellers who were early adopters to get their insight and advice about how to use gen A