Tue.Oct 29, 2024

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Novartis' Scemblix leaps into newly diagnosed leukemia—where winning over doctors may take time

Fierce Pharma

Exactly three years after an initial FDA green light for the third-line treatment of leukemia, Novartis’ Scemblix has won an accelerated approval to treat newly diagnosed patients. | Exactly three years after an initial FDA green light for the third-line treatment of leukemia, Novartis’ Scemblix has won an accelerated approval to treat newly diagnosed patients.

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MedCity FemFwd: How Doulas Can Improve Maternal Health Outcomes

MedCity News

In this episode, we’re joined by Dr. Tiffany Inglis, national medical director for women and children’s health at Carelon Health, a subsidiary of Elevance Health. Inglis discusses a paper Elevance Health Public Policy Institute recently published about doulas. The post MedCity FemFwd: How Doulas Can Improve Maternal Health Outcomes appeared first on MedCity News.

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Pfizer bumps up revenue outlook by $1.5B in Paxlovid rebound amid criticism from activist investor Starboard

Fierce Pharma

Amid a looming standoff with activist investor Starboard Value, Pfizer fought back against accusations of underperforming by delivering double digit revenue growth over the third quarter and notchi | The company is projecting yearly sales of $61 billion to $64 billion in a $1.5 billion boost from previous forecasts.

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Are You a Startup Looking for an Audience of Investors? We Have The Perfect Pitch Contest for You!

MedCity News

As companies begin to make plans for 2025, add the INVEST Pitch Perfect Contest to your calendar. The post Are You a Startup Looking for an Audience of Investors? We Have The Perfect Pitch Contest for You! appeared first on MedCity News.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Novartis' Pluvicto enters FDA orbit for expansion bid as agency requests 'flexibility'

Fierce Pharma

As expected, Novartis’ radioligand therapy Pluvicto crossed the blockbuster sales threshold with one quarter still left of 2024. | Novartis didn't use a priority review voucher for Pluvicto's key application in an earlier treatment setting of prostate cancer. The company made the decision in response to the FDA's request for "flexibility" in its review timeline, Novartis CEO Vas Narasimhan explained.

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Joy as NICE lifts restrictions on myeloma drug Elrexfio

pharmaphorum

Patients in England and Wales with multiple myeloma are celebrating a decision by NICE to relax strict restrictions on eligibility to receive Pfizer's Elrexfio.In June, the cost-effectiveness agency cleared the use of the BCMAxCD3 bispecific antibody with 'optimised guidance' that allowed it to be used for a narrower range of patients than was covered by the approved label for the drug.

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VBC, MA, FHIR and Modern Care

MedCity News

We know from everyday purchasing of goods and services that you have to combine what you’re getting with what you’re paying for that good or service. But how does this basic consumer supplier concept play out in US healthcare? The post VBC, MA, FHIR and Modern Care appeared first on MedCity News.

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Protega scores FDA nod for new dosage of abuse-deterrent opioid Roxybond

Fierce Pharma

The FDA has approved the first abuse-deterrent, immediate-release, 10 mg opioid tablet for pain management. The drug, Roxybond, has been approved in other dosages.

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Going In Reverse Is Faster Way Forward for Crescent Bio’s Cancer Immunotherapy

MedCity News

Crescent Biopharma is going public via a reverse merger with GlycoMimetics that will capitalize the combined company with $200 million. Crescent’s lead program is a bispecific antibody for cancer that replicates the properties of a Summit Therapeutics bispecific drug that recently trounced Merck’s blockbuster med Keytruda in a pivotal head-to-head study.

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Bristol Myers partner Zai Lab plots KarXT filing in China after trial win

Fierce Pharma

After the recent FDA approval for the promising schizophrenia drug Cobenfy (xanomeline and trospium chloride), Bristol Myers Squibb and its partners are moving fast to expand the global reach of th | In a phase 3 bridging study run by Zai Lab in China, Bristol Myers Squibb's KarXT helped schizophrenia patients chart a 9.2-point total-score reduction on the Positive and Negative Syndrome Scale versus placebo at week 5, teeing up a forthcoming regulatory filing.

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Increase Revenue With Better, Faster Sales Onboarding

Quotas need to be hit. Revenue goals need to be met. This reality makes shortening sales onboarding time a top priority. Organizations with a standard onboarding process boost employee retention by 58% and increase productivity by 50%. Unfortunately, many companies struggle with inefficient processes that lead to high turnover and missed revenue opportunities.

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AbbVie gets bigger in Alzheimer's R&D with Aliada takeover

pharmaphorum

AbbVie agrees a $1.4bn cash deal to acquire Aliada Therapeutics, adding another anti-amyloid antibody to its Alzheimer's pipeline.

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With Jakafi's patent cliff looming, Incyte looks to 2025 launches to bulk up revenue by decade's end

Fierce Pharma

Incyte’s blockbuster JAK inhibitor Jakafi has been driving the company’s sales for years now, with this quarter being no different. | Meanwhile, the company also scrapped plans to expand its topical JAK Opzelura into two other skin disorders.

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PHTI review of digital hypertension tools gives mixed results

pharmaphorum

An evaluation of digital health technologies for hypertension by the Peterson Health Technology Institute (PHTI) finds some provide a clinical benefit, while others are lacking.On the plus side, the health technology assessment (HTA) body has concluded that tools to help people manage their antihypertensive drug treatment can deliver benefits in reduced blood pressure.

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‘You Almost Have to Be Doing It’: Why Scott Gottlieb Thinks All Doctors Will Use LLMs Soon

MedCity News

Large language models will soon become a much bigger part of doctors’ clinical workflows, former FDA Commissioner Scott Gottlieb said Tuesday at the 3rd Annual Summit on the Future of Rural Health Care. The post ‘You Almost Have to Be Doing It’: Why Scott Gottlieb Thinks All Doctors Will Use LLMs Soon appeared first on MedCity News.

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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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NHS funding boost confirmed ahead of tomorrow's Budget

pharmaphorum

UK government confirms £1.8bn funding boost to NHS to cut waiting lists, including £1.

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A CEO’s Guide to AI Exploration: Transforming Organizations and Mindsets

MedCity News

Try a variety of LLM-based tools yourself. Understand the risks, limitations, and who is working on putting quality frameworks and guardrails in place. Engage your employees and partners in discussions about what might now be possible. The post A CEO’s Guide to AI Exploration: Transforming Organizations and Mindsets appeared first on MedCity News.

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Next-gen Virtual Tools for Education & Learning in the Life Sciences

Impetus Digital

Pharma-exclusive Webinar: Next-gen Virtual Tools for Education & Learning in the Life Sciences About the webinar Join us for one of three webinar sessions, tailored exclusively for Pharma leaders. Between November 18–20, we will delve into the future of educational tools in the life sciences industry. Our expert speakers will unveil the latest virtual tools that are reshaping how professionals engage with and educate HCPs, patients, and internal teams.

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WHO Activates Global Health Emergency Corp in Response to Mpox

PharmaTech

WHO and its partners are providing support to countries dealing with mpox outbreaks.

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Using Generative AI in Sales: Pros, Cons, and Considerations According to Sellers

Are your sellers unsure about using AI in their day-to-day workflows? Or are they eager to try but uncertain where to start? They might be asking: Which tasks are best suited for AI? How will using AI affect my relationship with my customers? With so many tools available, which ones are the most useful to me? To help answer these and other common questions about using AI during the sales cycle, we surveyed B2B sellers who were early adopters to get their insight and advice about how to use gen A

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Novartis pays $150m upfront for Monte Rosa degrader drug

pharmaphorum

The lengthening list of pharma alliances focused on molecular glue degraders has another entry after Novartis signed a deal with Monte Rosa Therapeutics worth up to $2.2 billion. The partnership – which has seen a $150 million upfront payment from Novartis alongside a pledge for up to $2.1 billion in milestones – gives the Swiss pharma group rights to Monte Rosa's VAV1-directed molecular glue degrader programme.

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MedTechVets at the 2024 MedTech Conference in Toronto

MedTechVets

OCT 29TH: From October 15th-17th, the MedTechVets team had an incredible experience at The MedTech Conference in Toronto, Canada. This event brought together key players from across the medtech industry, fostering collaboration and innovation, while also emphasizing the importance of diversity and inclusion. Throughout the conference, MedTechVets advocated for veterans in the workforce, built meaningful connections, and hosted our highly anticipated second annual breakfast panel, “Building

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Pfizer rebuffs Starboard criticism as it raises forecasts

pharmaphorum

Pfizer CEO Albert Bourla hit back at activist investor Starboard Value, saying measures to reset the pharma group are already well in hand

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AbbVie agrees $1.4 billion Alzheimer’s acquisition

European Pharmaceutical Review

AbbVie has signed to acquire the biotech Aliada Therapeutics for $1.4 billion. The deal enables the advancement of a potentially best-in-class disease-modifying therapy for Alzheimer’s. Dr Roopal Thakkar , Executive Vice President, Research and Development and Chief Scientific Officer, AbbVie, highlighted that neuroscience is one of AbbVie’s key growth areas.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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How AZ’s respiratory wins are ramping up for a bigger prize in COPD

PharmaVoice

As AstraZeneca builds up indications for Fasenra, an ongoing trial will determine whether the respiratory drug can make up for past stumbles in COPD.

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Pharma Advertising Strategies for Effective Brand Engagement

Pharma Marketing Network

Pharma advertising isn’t just about promoting products—it’s about reaching patients, caregivers, and healthcare professionals with valuable, meaningful information. With digital channels, evolving regulations, and changing patient expectations, creating an impactful advertising strategy can feel complex. In this article, we’ll explore key pharma advertising strategies that resonate with your audience, enhance brand engagement, and help you stay ahead in a competitive industry.

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BIO 2024: CDMOs Focus on Complex Technical Challenges to Boost Startup Biotechs

PharmaTech

Marianna Tcherpakov, PhD, director of Business Development, CMC Services, at Frontage Laboratories, spoke on the CDMO’s role in tackling complex technical challenges to enable startup biotechs solve scale up problems.

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FDA Approves Protega Pharmaceuticals’ Roxybond for Severe Pain Management

PharmExec

Roxybond is the and only FDA-approved abuse-deterrent immediate-release 10 mg oxycodone formulation designed to reduce abuse of pain medication via intranasal and intravenous routes.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Novartis and Monte Rosa Therapeutics Form $2.1 Billion Global License Agreement for MGD-based Therapeutics

PharmaTech

The collaboration aims to advance clinical development of a Phase I drug candidate, MRT-6160, and to explore other therapeutic opportunities across multiple indications.

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Long-Term Implications of Ongoing Drug Shortages

PharmExec

Scott Brunner, CEO, and Tenille Davis, Chief Advocacy Officer, of the Alliance for Pharmacy Compounding explore the potential long-term implications of the ongoing drug shortages for the healthcare system and patient care.

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Bavarian eyes Mpox vaccine label expansion to include toddlers, kickstarts Phase II trial

Pharmaceutical Technology

The registrational trial is expected to support the approval for Bavarian’s mpox/smallpox vaccine use in children 2-11 years of age.

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GSK Agrees to Terms to Acquire Novel Treatment for Autoimmune Diseases from Chimagen Biosciences

PharmExec

OncLive serves as the connection to oncology, including groundbreaking cancer news and interviews with top oncologists in multimedia formats.

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud