Thu.May 30, 2024

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BioNTech, flush with $145M from CEPI, looks to expand mRNA vaccine production in Africa

Fierce Pharma

As various efforts to produce next-generation vaccines in Africa are being carried forward by the likes of the World Health Organization (WHO) and the Bill & Melinda Gates Foundation, BioNTech | Under an expansion of the partners’ existing deal, the Coalition for Epidemic Preparedness Innovations (CEPI) is committing up to $145 million to bolster BioNTech’s efforts to establish vaccine R&D and manufacturing capabilities at the German company’s facility in Kigali, Rwanda.

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COVID-19 vaccinations now ‘alarmingly low’ in Europe

pharmaphorum

COVID-19 vaccination rates have fallen precipitously in Europe and should be ramped up this autumn so they are at least in line with influenza vaccine uptake.

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CSL Seqirus scores 4th award from US government for bird flu pandemic preparedness

Fierce Pharma

The United States Department of Health and Human Services has expanded its avian flu pandemic preparedness partnership with CSL Seqirus, lining up the vaccine specialist to

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Mental Health Inequities Could Cost $1.3 Trillion in 2040. How Can the Industry Prevent This?

MedCity News

Mental health inequities are costing the U.S. $477.5 billion annually. This could rise to $1.3 trillion in 2040 if left unaddressed. The post Mental Health Inequities Could Cost $1.3 Trillion in 2040. How Can the Industry Prevent This? appeared first on MedCity News.

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AI Strategies for Sales Managers: How to Cut Down on Tedious Admin Work

What if you could help your sellers stop wasting 72% of their day on non-selling activities and focus on bringing in revenue? Incorporating AI in your enablement workflows can help you cut down on busy work, get projects done faster, and let your team (and you!) focus on making a bigger impact. We put together this guide to show you how to use AI to cut time and costs for projects, including collateral creation, development of training videos, and automating tedious processes.

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Gilead's Trodelvy suffers double whammy as failed bladder cancer trial raises flag over early deaths

Fierce Pharma

In the span of half a year, Gilead Sciences' Trodelvy has flopped a second phase 3 trial. | Following a high-profile lung cancer setback in January, Gilead said Thursday that Trodelvy also failed to move the needle in a bladder cancer study. The flop threatens the ADC's accelerated approval in the tumor type.

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Protect Personalized, Independent Kidney Care

MedCity News

A pending CMS policy could cause havoc for independent kidney care facilities and patients who need life-sustaining treatments. The post Protect Personalized, Independent Kidney Care appeared first on MedCity News.

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Plenful Raises $17M to Help Curb Rising Levels of Pharmacy Burnout

MedCity News

Plenful has completed a $17 million Series A funding round, bringing its total fundraising amount to date to more than $25 million. The startup offers a software platform that automates the manual and administrative tasks that burden pharmacists and pharmacy technicians. The post Plenful Raises $17M to Help Curb Rising Levels of Pharmacy Burnout appeared first on MedCity News.

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Verona's ensifentrine will be a 'paradigm shift in COPD treatment,' GlobalData says

Fierce Pharma

With a target date for FDA approval less than a month away, Sanofi and Regeneron’s megablockbuster Dupixent has gained much attention as it is on the verge of becoming the first biologic to treat c | With Verona Pharmaceuticals' COPD candidate ensifentrine approaching its FDA decision date, GlobalData has referred to it as a “paradigm shift in COPD treatment.

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US Congress passes bill to end Parkinson’s disease

pharmaphorum

The US Congress has passed the first-ever federal bill dedicated to ending Parkinson’s disease, modelled on similar legislation for Alzheimer’s enacted in 2011

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ASCO: Novartis' Scemblix proves edge over predecessor Gleevec in newly diagnosed leukemia

Fierce Pharma

With results from a head-to-head study comparing its newer chronic myeloid leukemia (CML) treatment Scemblix to its own standard-of-care tyrosine kinase inhibitor (TKI) Gleevec in newly diagnosed p | Newly diagnosed chronic myeloid leukemia patients on Scemblix achieved a major molecular response rate of 68% at 48 weeks compared to 49% for older drugs, including Novartis' established Gleevec.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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The Vital Role of Hospitals in Tackling Health Inequities

MedCity News

Hospitals and health systems stand at the forefront of advancing health equity and carry the heavy responsibility of treating illness while promoting wellness and reducing disparities in health outcomes. The post The Vital Role of Hospitals in Tackling Health Inequities appeared first on MedCity News.

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ASCO: Gilead looks for silver lining in Trodelvy’s failed lung cancer trial. But will the FDA play ball?

Fierce Pharma

Gilead Sciences is drawing back the curtain on the Trodelvy lung cancer data that previously caused a 10% slide in the company’s stock price. | Gilead Sciences is drawing back the curtain on the Trodelvy lung cancer data that previously caused a 10% slide in the company’s stock price. In sharing the detailed results, the company is hanging onto a positive sign in a subgroup of patients who have a high unmet medical need.

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CinRx Pharma Corrals $73M to Continue ‘Hub and Spoke’ Model of Startup Formation

MedCity News

CinRx Pharma’s most prominent spinout is CinCor Pharma, which was acquired by AstraZeneca last year. The startup creator will apply its new capital toward current programs and to expand to additional areas of unmet medical need. The post CinRx Pharma Corrals $73M to Continue ‘Hub and Spoke’ Model of Startup Formation appeared first on MedCity News.

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As Senate’s gaze lands on patents, a former US PTO chief calls the effort a ‘broad misunderstanding’

PharmaVoice

To lower drug prices, lawmakers are turning to the drug patent system to outlaw some common practices — but a former patent agency director says it’s the wrong way to go.

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How to Prove Marketing Value: Demonstrate Content ROI and Contribution to Sales

Every marketer knows how important it is to prove their efforts drive sales opportunities, but that’s easier said than done. When problems like sales and marketing misalignment, lack of data, and wasted efforts persist, marketers can’t measure, prove, or increase their impact on revenue at a time when demonstrating marketing value is critical. Using analyst and expert data, this guide to marketing impact and content attribution explains: How B2B buyers use content The most common types of conten

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First patient gets bowel cancer jab in NHS 'matchmaker' push

pharmaphorum

The first patient has received a BioNTech colorectal cancer vaccine as part of the NHS Cancer Vaccine Launch Pad (CVLP) 'matchmaker' service

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Here’s Why VC Judges Chose These 4 Startups as INVEST Pitch Perfect Winners

MedCity News

A group of 24 novel startups were selected to pitch at MedCity News’ INVEST conference in Chicago. Here’s four that VC judges chose as the winners in their respective tracks. The post Here’s Why VC Judges Chose These 4 Startups as INVEST Pitch Perfect Winners appeared first on MedCity News.

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J&J shares data on would-be blockbuster antidepressant

pharmaphorum

Johnson & Johnson's seltorexant hits the mark in a phase 3 trial involving patients with depression and sleep disturbances

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Pharma Pulse 5/30/24: Merck to Acquire EyeBio, Financial Burden of Private Healthcare Increased Over the Past Two Decades & more

Pharmaceutical Commerce

The latest news for pharma industry insiders.

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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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FDA approves Teva Pharmaceuticals’ AUSTEDO XR for TD and HD chorea

Pharmaceutical Technology

The US FDA approved Teva Pharmaceuticals’ AUSTEDO XR as a once-daily treatment option for tardive dyskinesia and Huntington’s disease chorea.

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NHS announces hospitals will roll out ‘Martha’s Rule’ as part of patient safety initiative

PharmaTimes

The first phase of the programme will be in place in hospitals across the UK by March 2025

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The Impact of Serialization Technology: Ensuring Product Integrity and Regulatory Compliance

Pharmaceutical Commerce

These advancements continue to act as a key driver in helping to boost the security, efficiency, and innovation of global industries, include pharma.

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Researchers identify genetic changes responsible for rare childhood immune disorders

PharmaTimes

Affecting the immune system, various forms of SCID are estimated to affect one in 75,000 to 100,000 newborns

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Increase Revenue With Better, Faster Sales Onboarding

Quotas need to be hit. Revenue goals need to be met. This reality makes shortening sales onboarding time a top priority. Organizations with a standard onboarding process boost employee retention by 58% and increase productivity by 50%. Unfortunately, many companies struggle with inefficient processes that lead to high turnover and missed revenue opportunities.

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Rapid Sterility Methods for CAR T-cell Therapies

PharmaTech

A combination of rapid sterility methods with the industry standard compendial method should ensure maximum safety.

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Innovative nanocage promises sustainable cancer drug delivery

European Pharmaceutical Review

A novel drug delivery method combining proline and metal such as palladium, could enable chemotherapy drugs to be transported in the body via nano-sized cages. Practically, this could enable delivering the structure “more directly” to a tumour, while “shielding healthy cells”. Chemotherapy drugs, antibiotics, as well as antivirals could be transported using this delivery system , the authors theorised.

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Move over CAR-T: The potential of NK cells in cell therapy

pharmaphorum

In this podcast interview with Dr. Fred Aslan from Artiva Biosciences, explore the potential of NK cells in cell therapy and how they could revolutionise the field of immunotherapy beyond CAR-T therapies.

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Enzene to Launch Drug Discovery Division at BIO 2024

PharmaTech

The company’s new division will provide end-to-end integrated discovery services.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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Lilly’s Retevmo cleared for RET-positive child cancers

pharmaphorum

The US FDA has given accelerated approval for Eli Lilly’s RET inhibitor as a treatment for various RET-altered paediatric cancers, making it the first drug in the class available for children aged under 12. Retevmo (selpercatinib) can now be used to treat RET-positive thyroid cancers and other solid tumours with the mutation, regardless of their type.

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FDA Approves Interchangeable Biosimilar to Soliris

PharmaTech

Bkemv (eculizumab-aeeb) is the first interchangeable biosimilar to Soliris (eculizumab) to treat paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome.

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BioNTech and CEPI expand deal to boost Africa’s vaccine capabilities

Pharmaceutical Technology

BioNTech and CEPI have announced an expansion of their strategic partnership, aiming to strengthen the mRNA vaccine ecosystem in Africa.

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Pharma Horizons: Cell and Gene Therapy

European Pharmaceutical Review

Download this report to discover key developments impacting cell and gene therapy (CGT) manufacturing. Articles explore how the rapid expansion of the cell and gene therapy field has affected skills, recruitment and training needs; delve into manufacturing and quality requirements for CGTs, and explore how these new modalities are transforming clinical trials.

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Using Generative AI in Sales: Pros, Cons, and Considerations According to Sellers

Are your sellers unsure about using AI in their day-to-day workflows? Or are they eager to try but uncertain where to start? They might be asking: Which tasks are best suited for AI? How will using AI affect my relationship with my customers? With so many tools available, which ones are the most useful to me? To help answer these and other common questions about using AI during the sales cycle, we surveyed B2B sellers who were early adopters to get their insight and advice about how to use gen A