Wed.Mar 20, 2024

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BioNTech's shares tumble—again—amid continued COVID vaccine sales slide

Fierce Pharma

Four months ago, when BioNTech slashed its 2023 revenue projection from 5 billi | When BioNTech reported its fourth-quarter earnings Wednesday, it was another harsh reminder of the plummeting demand for COVID-19 vaccines. Sales came to 1.5 billion euros ($1.6 billion) for the fourth quarter and 3.8 billion euros ($4.1 billion) for 2023, coming up short of expectations.

Sales 335
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FDA approves innovative gene therapy for MLD

European Pharmaceutical Review

The US Food and Drug Administration (FDA) has approved gene therapy Lenmeldy (atidarsagene autotemcel) as the first treatment for children with early-onset metachromatic leukodystrophy (MLD). Following a patient receiving chemotherapy, the autologous hematopoietic stem cell-based gene therapy is administered as a personalised, one-time, single-dose infusion.

FDA 105
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Johnson & Johnson accuses former employee of taking thousands of files to new role at Pfizer

Fierce Pharma

As two of the world’s largest pharmaceutical companies, Johnson & Johnson and Pfizer have long been rivals in various therapeutic areas. | The company is accusing former employee Andrew Brackbill of downloading thousands of confidential strategy-related files before leaving for rival Pfizer.

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Lonza to acquire major biologics manufacturing facility

European Pharmaceutical Review

Lonza has agreed to acquire one of the world’s largest biologics manufacturing sites (by volume), for a total of $1.2 billion from Roche. The acquisition of the manufacturing facility will significantly increase Lonza’s capacity of the manufacture of large-scale biologics, to meet demand for commercial mammalian contract manufacturing. At present, the Genentech Vacaville facility in the US has a total bioreactor capacity of around 330,000 litres.

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AI Strategies for Sales Managers: How to Cut Down on Tedious Admin Work

What if you could help your sellers stop wasting 72% of their day on non-selling activities and focus on bringing in revenue? Incorporating AI in your enablement workflows can help you cut down on busy work, get projects done faster, and let your team (and you!) focus on making a bigger impact. We put together this guide to show you how to use AI to cut time and costs for projects, including collateral creation, development of training videos, and automating tedious processes.

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Idorsia's Tryvio crosses FDA finish line, offering new mechanism to treat hypertension

Fierce Pharma

After Johnson & Johnson last year changed its mind on its 2017 purchase of ap | Idorsia's Tryvio is the first oral anti-hypertensive therapy that uses a new therapeutic mechanism in nearly 40 years, suggesting the dawn of "a new era of endothelin research," the company said.

FDA 291
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Vicore’s lung disease digital therapy gets breakthrough tag

pharmaphorum

Vicore gets FDA breakthrough status for Almee, a cognitive behavioural therapy (CBT) digital health therapy used to support people with pulmonary fibrosis

FDA 113

More Trending

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Why Are Most Provider-Sponsored Health Plans Unprofitable?

MedCity News

The “vast majority” of provider-sponsored health plans are unprofitable, Flare Capital Partners Principal Parth Desai pointed out during a recent interview. He said most of these plans aren’t able to cover the large number of lives required to ensure a viable risk pool and maintain a healthy operating margin.

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After Opdivo flop in liver cancer, Bristol Myers finds Yervoy combo could save lives

Fierce Pharma

Bristol Myers Squibb is gunning for newly diagnosed unresectable liver cancer—again—after an immunotherapy setback five years ago. | Bristol Myers Squibb is gunning for newly diagnosed unresectable liver cancer—again—after its Opdivo monotherapy setback five years ago and a subsequent market withdrawal.

Marketing 273
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Germany largest revenue contributor in Europe’s LIMS market

European Pharmaceutical Review

According to a report by Arizton, the Europe laboratory information management system (LIMS) market is expected to reach $912.47 million by 2028. The market is growing at a CAGR of 10.16 percent between 2022-2028, the research found. Factors shaping the market partnerships and collaborations “promise huge demand and growth opportunities for small and medium-sized firms to enter the [European LIMS] market” With pharmaceutical and biotechnological industries making large R&D investments, the

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With exec appointments and new pharma unit, Bayer's overhaul takes shape

Fierce Pharma

Early this month at an investor event, Bayer CEO Bill Anderson—the agent for reform of the troubled company—declared that employees “are ready for change. They’re saying bring it on.” | Early this month at an investor event, Bayer CEO Bill Anderson declared that employees “are ready for change." On Wednesday, Anderson answered the call with changes to the company’s leadership.

Pharma 261
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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What Are the Challenges Facing the Pharmacy Industry Right Now?

MedCity News

The regulatory environment and workforce shortages are plaguing the pharmacy industry, one Walgreens exec shared at the Abarca Forward conference on Tuesday.

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Johnson & Johnson’s paediatric HIV-1 treatment secures FDA approval

Pharmaceutical Technology

Johnson & Johnson has received approval from the FDA for EDURANT PED to treat human immunodeficiency virus-1 (HIV-1) in children.

FDA 110
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Startup Lands $150M for Delicate Dance Between Cancer Cells & Immune Cells

MedCity News

Clasp Therapeutics’ novel T cell engagers could offer advantages over others in this class of cancer immunotherapies. The startup is based on the research of Johns Hopkins University scientist Bert Vogelstein.

Biopharma 105
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Researchers suggest treatments for rare diseases could reduce burden of kidney disease

PharmaTimes

Rare kidney diseases are a group of conditions which account for over 5% of people living with chronic kidney disease

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How to Prove Marketing Value: Demonstrate Content ROI and Contribution to Sales

Every marketer knows how important it is to prove their efforts drive sales opportunities, but that’s easier said than done. When problems like sales and marketing misalignment, lack of data, and wasted efforts persist, marketers can’t measure, prove, or increase their impact on revenue at a time when demonstrating marketing value is critical. Using analyst and expert data, this guide to marketing impact and content attribution explains: How B2B buyers use content The most common types of conten

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EU pharma legislation reforms inch closer to fruition

pharmaphorum

EU pharma legislation gets closer to fruition as European Parliament's ENVI committee votes in favour of amendments, but industry remains concerned

Pharma 96
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Hubs East 2024: Leveraging Digital Hubs

Pharmaceutical Commerce

Presentation offers insight on this aforementioned model that assists retail and specialty-lite brands.

Retail 102
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Orchard’s MLD gene therapy becomes costliest US medicine

pharmaphorum

Orchard Therapeutics has revealed the US price of Lenmeldy, its gene therapy for rare disease MLD, placing a $4.

Medicine 109
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Breaking Down Barriers to Obesity Care

MedCity News

How targeted outreach and heightened engagement can help companies achieve better outcomes

Patients 114
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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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Lonza adds biologics capacity with $1.2bn Roche deal

pharmaphorum

Swiss CDMO Lonza pays $1.2bn for Roche's biologics manufacturing facility in Vacaville, US, safeguarding around 750 jobs.

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Unlocking U.K. research excellence: Key insights from the Research Professional News Live summit

Clarivate

Discover pivotal insights shaping the landscape of U.K. research shared at the second Research Professional News Live summit. From discussions on REF2029 to the imperatives of fostering diversity, innovation and research integrity, we explored the future of research amidst financial challenges and evolving policies. On March 14, the Research Professional News Live summit brought together a stellar group of speakers, panelists and delegates including keynotes from Professor Dame Jessica Corner, E

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Gates, Wellcome-backed TB vaccine starts phase 3 trial

pharmaphorum

A highly anticipated phase 3 trial of a new tuberculosis vaccine developed by GSK has started in Africa, funded by the Gates MRI and Wellcome.

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ebook: A practical guide to single-use filtration in biopharma

European Pharmaceutical Review

Single-use filtration systems can help streamline processes and enhance efficiency of biopharma production. In this practical guide readers will embark on a journey through pre-filtration and sterile filtration stages, gaining insight into diverse membrane technologies. Download this ebook to: Uncover how pore size and membrane material can be used to tailor filtration processes Learn how to optimise flow rates to balance efficiency and quality Discover how single-use filtration systems can boos

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Increase Revenue With Better, Faster Sales Onboarding

Quotas need to be hit. Revenue goals need to be met. This reality makes shortening sales onboarding time a top priority. Organizations with a standard onboarding process boost employee retention by 58% and increase productivity by 50%. Unfortunately, many companies struggle with inefficient processes that lead to high turnover and missed revenue opportunities.

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Iclusig gets FDA nod as frontline therapy for rare leukaemia

pharmaphorum

Takeda’s Iclusig is first targeted therapy approved by the FDA for use alongside chemo as a first-line therapy for acute lymphoblastic leukaemia

FDA 88
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New study reveals neurological conditions as leading cause of ill health worldwide

PharmaTimes

In 2021, neurological conditions, including Alzheimer's disease, affected approximately 3.

Leads 88
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FDA approves Boehringer’s SPEVIGO for psoriasis treatment

Pharmaceutical Technology

The US Food and Drug Administration (FDA) has granted approval for Boehringer Ingelheim's SPEVIGO injection to treat generalised pustular psoriasis (GPP).

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Why Traditional Sales Role Play Falls Short

Quantified

The internet is full of statistics that demonstrate how vital sales training is. Whether you’re measuring the productivity of each agent, the total ROI of training initiatives, or the percentage increase of closed-won deals, training makes a sizeable difference. The trick is identifying which training methods are contributing to increases and, whenever possible, which training exercises contribute the most to sales success.

Sales 52
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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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Phosgene at Valsynthese: An Atom-Economic Reagent That Demonstrates Exceptional Versatility (March 2024)

PharmaTech

Dr. Luca Mantilli, an R&D chemist at Valsynthese, shares his insights into the company’s journey with phosgene, an exceptionally versatile reagent that offers various synthetic possibilities.

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Orchard sets out to sell world’s priciest gene therapy

PharmaVoice

Orchard is counting on the long-term data it’s accrued to convince insurers to cover Lenmeldy’s $4.25 million list price, the highest of any genetic medicine to come to market.

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PAP 2024: Amy Niles Discusses Moderating the State of Patient Access and Affordability Breakout Session

Pharmaceutical Commerce

In an interview with Pharma Commerce Associate Editor Don Tracy, Amy Niles, Chief Mission Officer, PAN Foundation offers her thoughts on the session and feedback from the audience at PAP 2024 in Philadelphia.

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What is Neurosurgery Device Sales? with Eddie Cortez

Evolve Your Success

Unlock the secrets of thriving in the competitive world of medical sales with Eddie Cortez of Integra Life Sciences’ Neurosurgery West Division. Join us as Eddy, with his 14 years of experience, shares the journey from the front lines in the operating room to leading a sales team, providing a rare glimpse into the dynamic space of neurosurgical product sales.

Sales 52
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Using Generative AI in Sales: Pros, Cons, and Considerations According to Sellers

Are your sellers unsure about using AI in their day-to-day workflows? Or are they eager to try but uncertain where to start? They might be asking: Which tasks are best suited for AI? How will using AI affect my relationship with my customers? With so many tools available, which ones are the most useful to me? To help answer these and other common questions about using AI during the sales cycle, we surveyed B2B sellers who were early adopters to get their insight and advice about how to use gen A