Thu.Jan 18, 2024

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After Pfizer offers discount, NICE gives thumbs up to breast cancer drug Talzenna

Fierce Pharma

Six months after England’s National Institute for Health and Care Excellence (NICE) spurned Pfizer’s breast cancer treatment Talzenna (talazoparib) because it was not cost effective, the agency has | Six months after England’s National Institute for Health and Care Excellence spurned Pfizer’s breast cancer treatment Talzenna because it was not cost effective, the agency has reversed course following the company’s offer to slash the price.

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How Can AI Support Value-Based Care?

MedCity News

During a panel discussion at CES 2024, health executives shared safe ways AI can be used to support value-based care. This includes automating tasks and predicting who needs additional care.

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Senators threaten to subpoena CEO testimony while J&J, Merck claim retaliation amid IRA legal fight

Fierce Pharma

In its efforts to probe high U.S. drug prices, the Senate health committee has already heard from the heads of Moderna, Eli Lilly, Novo Nordisk and Sanofi. | The Senate Committee on Health, Education, Labor, and Pensions will vote on issuing subpoenas at the end of the month after the Johnson & Johnson and Merck CEOs refused to testify at an upcoming hearing.

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Gearing Up to Challenge Pfizer in a Rare Disease, BridgeBio Secures Up to $1.25B

MedCity News

BridgeBio will receive $500 million in exchange for royalties from sales of acoramidis, a drug currently under FDA review for treating heart complications caused by the rare disease transthyretin amyloidosis. The deal also refinances lending agreements, providing BridgeBio with access to additional capital.

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AI Strategies for Sales Managers: How to Cut Down on Tedious Admin Work

What if you could help your sellers stop wasting 72% of their day on non-selling activities and focus on bringing in revenue? Incorporating AI in your enablement workflows can help you cut down on busy work, get projects done faster, and let your team (and you!) focus on making a bigger impact. We put together this guide to show you how to use AI to cut time and costs for projects, including collateral creation, development of training videos, and automating tedious processes.

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Fierce Pharma Asia—Roche's TIGIT readout; Daiichi's ADC patent win; LegoChem's $411M raise

Fierce Pharma

Roche's TIGIT antibody has posted a positive phase 3 result that probably won't lead anywhere. In a win for Daiichi Sankyo, a U.S. agency has invalidated a Seagen patent. | Roche's TIGIT antibody has posted a positive phase 3 result that probably won't lead anywhere. In a win for Daiichi Sankyo, a U.S. agency has invalidated a Seagen patent.

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Bayer’s Cost-Cutting Plans Take Aim at Multiple Layers of Management

MedCity News

CEO Bill Anderson said despite prior cost-cutting measures, Bayer still has too many layers of management and bureaucracy. A new restructuring will come with layoffs but the corporate shakeup plan does not yet include a separation of Bayer’s business units.

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Profitability Is King in 2024’s Fundraising Environment, Expert Says

MedCity News

This year’s digital health fundraising environment requires startups to focus more on their unit economics and pathway to profitability, according to Ian Wijaya, managing director at Lazard. He predicted that the ability to achieve profitability will be much more important in 2024 than it has been in the past four years or so.

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Novartis eyes $1B Lutathera acceleration with trial win in newly diagnosed neuroendocrine tumors

Fierce Pharma

Novartis hopes new data will open a $1 billion market opportunity for its radioligand therapy, Lutathera, as a first-line treatment. | Novartis hopes new data will open a $1 billion market opportunity for its radioligand therapy, Lutathera, as a first-line treatment. Friday, the company's ambition received a boost from the phase 3 readout of the NETTER-2 trial.

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FDA clears AI skin cancer detection device from DermaSensor

pharmaphorum

Medtech company DermaSensor gets FDA approval for a handheld device, powered by AI, that can be used to detect skin cancer at the point of care

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AstraZeneca charts new course for Imfinzi in liver cancer, but FDA path remains uncertain

Fierce Pharma

AstraZeneca charts new course for Imfinzi in liver cancer, but FDA path remains uncertain aliu Thu, 01/18/2024 - 14:27

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Winners named in NHS healthcare inequality contest

pharmaphorum

AI-powered patient risk assessment company C2-Ai and the Sickle Cell Society have won an NHS contest to find solutions that can tackle health inequality

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'The Top Line': A closer look at the bounty of new drug approvals in 2023

Fierce Pharma

At Fierce Pharma, the arrival of a new year is synonymous with the release of our annual special report on drug approvals. | At Fierce Pharma, the arrival of a new year is synonymous with the release of our annual special report on drug approvals. This week on “The Top Line,” Fierce Pharma’s Eric Sagonowsky and Kevin Dunleavy, both instrumental in creating the special report, are breaking down the numbers and sharing key insights into the landscape of drug approvals in 2023.

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NICE backs Pfizer’s Talzenna for advanced breast cancer

pharmaphorum

Pfizer’s PARP inhibitor Talzenna has become the first targeted treatment for HER2-negative locally advanced or metastatic breast cancer with BRCA1/2 mutations to be recommended by NICE for routine NHS use.

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UK ATMP sector “robust”, research finds

European Pharmaceutical Review

An attractive destination for ATMP clinical trials Based on the Cell and Gene Therapy Catapult (CGT Catapult)’s recently published UK 2023 Advanced Therapy Medicinal Product (ATMP) Clinical Trials Database , the UK is an attractive location for ATMP clinical trials. This is largely due to the number of ongoing ATMP clinical trials in the UK remaining “largely stable” over the past three years.

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How to Prove Marketing Value: Demonstrate Content ROI and Contribution to Sales

Every marketer knows how important it is to prove their efforts drive sales opportunities, but that’s easier said than done. When problems like sales and marketing misalignment, lack of data, and wasted efforts persist, marketers can’t measure, prove, or increase their impact on revenue at a time when demonstrating marketing value is critical. Using analyst and expert data, this guide to marketing impact and content attribution explains: How B2B buyers use content The most common types of conten

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TBD Health Partners with Wisp, FOLX Health To Offer Access to Testing and Diagnostics

MedCity News

TBD Health is moving into the B2B healthcare space by partnering with digital health companies, starting with FOLX Health and Wisp.

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Sun Pharma reaches deal to buy out Taro in $347m deal

pharmaphorum

India’s Sun Pharma has signed an agreement to take full control of Israeli generic drugmaker Taro Pharmaceutical Industries, taking it into private hands.

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10 Key MedTech Themes for 2024

MedCity News

Increasing innovation in, and consumer demand for, healthcare technology continue to transform the Medtech industry, including in digital health, wearables, diagnostics, telemedicine and other health IT solutions.

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BridgeBio raises $1.25bn, and other biotech financings

pharmaphorum

BridgeBioPharma raises $1.

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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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Disruption from Weight Loss Drugs Has Only Scratched the Surface. Telehealth Can Help Overcome the Next Big Obstacle

MedCity News

Telehealth is poised to serve as an essential tool to fill an exploding demand for care. Providers and digital health companies need to act now by expanding telehealth offerings that include on-demand care teams knowledgeable and experienced in GLP-1 drugs, but also overall health and wellness strategies.

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UCB announces MHRA approval for UCB’s Zilbrysq

PharmaTimes

Green light concerns generalised myasthenia gravis therapy

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The Impact of Eli Lilly's New DTC Platform on Rx Drug Sales and Patient Access: An Interview with Bill Roth, General Manager, Managing Partner, Blue Fin Group

Pharmaceutical Commerce

In an interview with Pharma Commerce editor Nicholas Saraceno, Bill Roth, General Manager, Managing Partner, Blue Fin Group, discusses changes that will come with the pharma giant's new platform.

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Bayer reaches deal on shedding management layers

pharmaphorum

Bayer has reached a deal with union representatives that will result in a sizeable reduction in managerial roles

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Increase Revenue With Better, Faster Sales Onboarding

Quotas need to be hit. Revenue goals need to be met. This reality makes shortening sales onboarding time a top priority. Organizations with a standard onboarding process boost employee retention by 58% and increase productivity by 50%. Unfortunately, many companies struggle with inefficient processes that lead to high turnover and missed revenue opportunities.

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Market outlook to 2032: future trends across the seven major markets

European Pharmaceutical Review

The treatment markets for two key diseases areas: insomnia and the rare metabolic disorder, Gaucher disease, are predicted to flourish in the seven major markets (7MM – France, Germany, Italy, Spain, UK, US, and Israel) in 2032, data and analytics company GlobalData suggests. Insomnia market Dual orexin receptor antagonists (DORAs) [dual orexin receptor antagonists (DORAs)]… offer a new mechanism of action [in treating insomnia]” Across the seven major markets, the insomnia mar

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Synendos receives EMA nod for brain therapy

PharmaTimes

Company is focused on endocannabinoid system treatments

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Long-term findings from CAR NK cell therapy trial revealed

European Pharmaceutical Review

US researchers have reported promising outcomes from a Phase I/II trial in cancer patients treated with cord blood-derived CD19-targeted chimeric antigen receptor (CAR) natural killer (NK) cell therapy. Published in Nature Medicine , the findings revealed an overall response (OR) rate of 48.6 percent at 100 days post treatment. The one-year progression-free survival (PFS) and overall survival (OS) rates were reported to be 32 percent and 68 percent, respectively, in patients with relapsed or re

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Synendos set to study endocannabinoid inhibitor for neuropsychiatric conditions

Pharmaceutical Technology

The endocannabinoid inhibitor SYT-510 will be investigated in healthy patients to assess its safety, tolerability, and pharmacokinetics.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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Study: Ultraviolet Light Could Destroy Coronavirus Particles

Pharmacy Times

The researchers found that the genomic material was extremely sensitive to the degradation.

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CDER Approved 55 Novel Drugs in 2023

PharmaTech

FDA’s Center for Drug Evaluation and Research released its report on new drugs approved in 2023.

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No Significant Differences in Efficacy Shown Between Reference Drug, Biosimilars in Patients With IBD

Pharmacy Times

Despite the insignificant differences in efficacy, biomarkers, therapeutic drug level, and ADAs, patients reported a significant number of nocebo effects.

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Novartis Acquires Calypso Biotech for up to $425 Million

PharmaTech

The acquisition will give Novartis full rights to CALY-002, Calypso’s lead product candidate.

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Using Generative AI in Sales: Pros, Cons, and Considerations According to Sellers

Are your sellers unsure about using AI in their day-to-day workflows? Or are they eager to try but uncertain where to start? They might be asking: Which tasks are best suited for AI? How will using AI affect my relationship with my customers? With so many tools available, which ones are the most useful to me? To help answer these and other common questions about using AI during the sales cycle, we surveyed B2B sellers who were early adopters to get their insight and advice about how to use gen A