Wed.Nov 29, 2023

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Amgen expands pact with Amazon to usher drug manufacturing into the AI era

Fierce Pharma

Seeking to identify ways to improve the discovery and production of medicines, Amgen is expanding its partnership with tech giant Amazon. | Amgen is growing its decade-old collaboration with Amazon Web Services—a widely used cloud platform—to create generative artificial intelligence that the companies aim to use to increase the manufacturing throughput of pharmaceuticals.

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GE HealthCare Launches New AI Suite to Catch Breast Cancer Sooner

MedCity News

At RSNA 2023, GE HealthCare announced the launch of a new AI suite designed to simplify radiologists’ workflows when reading mammograms and help them detect breast cancer in patients sooner. The new offering includes three AI tools made by iCAD.

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As FDA probes CAR-T safety, expert meeting for Bristol's Abecma could serve as key guidepost

Fierce Pharma

The revelation of an FDA investigation< | As industry watchers deliberate the implications from the FDA's investigation into secondary cancer risks from CAR-T medicines, an upcoming expert meeting could offer precious clarity from drug regulators.

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Ferring reveals long-term data for cancer gene therapy

European Pharmaceutical Review

Following the US Food and Drug Administration (FDA)’s approval of Ferring Pharmaceuticals’ gene therapy Adstiladrin ® (nadofaragene firadenovec-vncg) in December 2022, new long-term follow up data has been revealed. Adstiladrin is the first FDA-approved intravesical gene therapy to be authorised for adults with high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) with or without papillary tumours.

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AI Strategies for Sales Managers: How to Cut Down on Tedious Admin Work

What if you could help your sellers stop wasting 72% of their day on non-selling activities and focus on bringing in revenue? Incorporating AI in your enablement workflows can help you cut down on busy work, get projects done faster, and let your team (and you!) focus on making a bigger impact. We put together this guide to show you how to use AI to cut time and costs for projects, including collateral creation, development of training videos, and automating tedious processes.

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FDA Investigating Risk of Secondary Cancers in Patients Administered CAR T-Cell Therapy

PharmExec

The FDA will investigate all currently approved CAR T-cell treatments, as well as BCMA-directed and CD19-directed genetically modified autologous CAR T-cell therapies, for the risk of secondary T-cell malignancies.

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Report: Global Healthcare Benefit Costs Expected to Rise 9.9% in 2024

MedCity News

Globally, health benefit costs are expected to increase 9.9% in 2024, according to a new report from Willis Towers Watson. This is a slightly slower pace than in 2023, which saw a record-high increase of 10.7%.

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Beyond QA: The Next Wave of Medical Chatbots

MedCity News

Medical chatbots have the potential to shape the future of healthcare data retrieval and decision-making support. But this can’t become a reality unless precautions are taken to make sure the answers are both grounded in reality and extracted from reliable sources.

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CSL, Arcturus get first approval for self-assembling RNA jab

pharmaphorum

Japan’s medicines regulator has approved the first vaccine based on self-assembling RNA, a spin on the mRNA technology used in current shots, which is designed to deliver greater efficacy with a lower dose.

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Japan grants approval for CSL and Arcturus’ Covid-19 vaccine 

Pharmaceutical Technology

Japan’s MHLW has approved CSL and Arcturus Therapeutics’ self-amplifying mRNA (sa-mRNA) Covid-19 vaccine, ARCT-154.

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Long Term Impact: How the Healthcare Industry Can Survive Staffing Shortages

MedCity News

By streamlining front-end processes, reducing errors, and ensuring prompt service delivery, AI and automation not only boost the patient experience but also optimize revenue streams.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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FDA kicks off review of Karuna’s schizophrenia drug KarXT

pharmaphorum

Karuna Therapeutics said this morning that the FDA has formally started its review of KarXT, aiming to become the first drug to reach the market for schizophrenia with a new mechanism of action in decades.

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MedCity Moves Podcast: Recent Hires, Layoffs & an Interview with Jeff Good, Chief Sustainability Executive at Northwestern Medicine

MedCity News

For the November episode, we discuss some recent executive hires and departures occurring in the healthcare sector, as well as layoffs affecting the industry. We also hear from Jeff Good, who just became Northwestern Medicine’s first chief sustainability executive.

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'High Severity' Flu Season Among Children Spotlights Importance of Vaccination

PharmExec

The CDC’s Morbidity and Mortality Weekly Report show pediatric influenza hospitalization rates returned to levels that preceded the COVID-19 pandemic.

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CMS: 4.6M Choose ACA Marketplace Coverage

MedCity News

Of those who have chosen ACA Marketplace coverage so far in the 2024 Open Enrollment Period, 20% are new consumers and 80% are returning consumers, according to CMS.

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How to Prove Marketing Value: Demonstrate Content ROI and Contribution to Sales

Every marketer knows how important it is to prove their efforts drive sales opportunities, but that’s easier said than done. When problems like sales and marketing misalignment, lack of data, and wasted efforts persist, marketers can’t measure, prove, or increase their impact on revenue at a time when demonstrating marketing value is critical. Using analyst and expert data, this guide to marketing impact and content attribution explains: How B2B buyers use content The most common types of conten

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VPAS is dead, long live VPAG—could the UK’s new clawback revision save the day?    

Pharmaceutical Technology

After months of negotiations, the UK's DHSC and the Association of the British Pharmaceutical Industry emerged with a plan on to replace VPAS.

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AbbVie cues up filing for c-Met ADC in lung cancer

pharmaphorum

AbbVie is preparing to file for accelerated approval of telisotuzumab vedotin (Teliso-V) as a treatment for some patients with lung cancer after the drug hit the mark in a pivotal phase 2 trial.

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Milner Therapeutics to establish new genomics laboratory for drug discovery

PharmaTimes

The new state-of-the-art facility is set to be operational in early 2024 - News - PharmaTimes

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What’s on the Horizon in Pharma Marketing & Innovation: Q&A With Faruk Capan, Chief Innovation Officer at EVERSANA

PharmExec

Capan discusses the industry is embracing new technologies and how these use cases may evolve in the coming year.

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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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FDA opens investigation into secondary cancer risk with CAR-T therapies

Pharmaceutical Technology

The agency has received reports of T-cell malignancies in patients who have previously received CAR-T cell immunotherapies.

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Pharma benefited from basing business overseas. An international tax effort could spur a rethink.

PharmaVoice

U.S. tax law changes six years ago slashed large pharma companies' rates and saved them billions. Now, a push for an international floor could disrupt their R&D accounting.

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Aro Biotherapeutics raises funds for Pompe disease treatment

Pharmaceutical Technology

Aro Biotherapeutics has raised $41.5m in a Series B financing round to advance the development of ABX1100 for Pompe disease.

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Shine rubs off Argenx after Vyvgart Hytrulo fails trial

pharmaphorum

Shine rubs off Argenx after Vyvgart Hytrulo fails trial Phil.

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Increase Revenue With Better, Faster Sales Onboarding

Quotas need to be hit. Revenue goals need to be met. This reality makes shortening sales onboarding time a top priority. Organizations with a standard onboarding process boost employee retention by 58% and increase productivity by 50%. Unfortunately, many companies struggle with inefficient processes that lead to high turnover and missed revenue opportunities.

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How to manage temperature-controlled shipments in unpredictable climate zones

Pharmaceutical Technology

Due to the increasing impact of climate change, drug packaging and shipping sectors have had to adapt by necessity.

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FDA to Evaluate Novel Treatment for Schizophrenia

Pharmaceutical Commerce

In clinical trials, KarXT (xanomeline-trospium) demonstrated a combination of strong tolerability and clinically meaningful symptom reduction in adult patients with schizophrenia.

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Vivos Therapeutics' Obstructive Sleep Apnea Oral Appliance Gains FDA 510(k) Clearance

PharmExec

Vivos becomes the first company to bring to market an alternative to continuous positive airway pressure (CPAP) or surgical neurostimulation implants for patients with severe OSA.

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Pharma’s path to Net Zero: Targeting Scope 3 emissions 

Pharmaceutical Technology

With a target of net zero for 2050, pharmaceutical companies need to tackle Scope 3 emissions, that make up the majority of their carbon footprint.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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Patient Advocate Engagement: A Customer Story

Impetus Digital

Learn how our client executed a series of 3 virtual touchpoints with 5 rare disease patient advocates to: Develop a b etter understanding of the current treatment landscape and lived patient experiences, including key gaps and unmet treatment needs. Design content for a virtual patient advisory board or needs assessment survey and leverage the results to educate research teams and healthcare providers on patients’ experiences and priorities.

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Cyclin Dependent Kinase 4 drugs in development, 2023

Pharmaceutical Technology

GlobalData’s report assesses the drugs in the Cyclin Dependent Kinase 4 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline.

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What Percentage of Sales Reps Hit Quota?

Sales Talent

This question doesn’t get asked often enough and has major implications. It impacts realistic earnings projections for salespeople, what companies should expect from their new hires’ sales performance, and ultimately, salesforce turnover rates. This topic recently came up in a conversation with Shane Jamison , a tech sales coach who works with earlier stage tech companies looking to scale.

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Bromodomain Containing Protein 4 drugs in development, 2023

Pharmaceutical Technology

GlobalData’s report assesses the drugs in the Bromodomain Containing Protein 4 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline.

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Using Generative AI in Sales: Pros, Cons, and Considerations According to Sellers

Are your sellers unsure about using AI in their day-to-day workflows? Or are they eager to try but uncertain where to start? They might be asking: Which tasks are best suited for AI? How will using AI affect my relationship with my customers? With so many tools available, which ones are the most useful to me? To help answer these and other common questions about using AI during the sales cycle, we surveyed B2B sellers who were early adopters to get their insight and advice about how to use gen A