Biopharma, Pharma and Side effects

Oral Metabolic Drug Acquired by Novo Nordisk Continues to Show Concerning Neuro Side Effects

MedCity News

FEBRUARY 5, 2025

Novo Nordisks monlunabant showed signs of neuropsychiatric side effects in a mid-stage diabetic kidney disease study, despite a drug design intended to favor hitting its target receptor in peripheral tissues rather than the brain. Neuro effects were also reported last year in a Phase 2 test of this pill in obesity.

Side effects

Side effects Biopharma Pharma

Side Effects are Limiting GLP-1 Drug Efficacy: How Can Personalization Offer a Solution?

MedCity News

AUGUST 22, 2024

By integrating digitization and machine learning, there is an opportunity to deliver personalized care to all patients and scale precision dosing with minimal physician involvement, maximizing the effectiveness and accessibility of these drugs. The post Side Effects are Limiting GLP-1 Drug Efficacy: How Can Personalization Offer a Solution?

Side effects

Side effects Physicians Patients Medicine

Serious Side Effect Sidelines Gene-Edited Sickle Cell Therapy from Graphite Bio

MedCity News

JANUARY 6, 2023

Graphite Bio voluntarily paused a Phase 1/2 test of its gene-edited therapy for sickle cell disease after the first patient in the study developed a serious blood complication. The setback will also delay plans to reach the clinic with another genetic medicine in its pipeline.

Side effects

Side effects Medicine Patients Biopharma

Can Herbal Alternatives Ease the Economic Burden of Weight Loss Drugs?

MedCity News

OCTOBER 23, 2024

For patients who may be unable to afford the high cost of GLP-1 obesity drugs or are worried about the side effects, it’s important for healthcare providers to offer education on herbal alternatives and consider these as part of the broader treatment conversation. appeared first on MedCity News.

Side effects

Side effects Healthcare Provider Education Healthcare

FDA Nod in Duchenne Helps Wider Swath of Patients With the Rare Muscle Disease

MedCity News

MARCH 22, 2024

Corticosteroids are a standard first-line treatment for Duchenne muscular dystrophy, but these drugs have many side effects. FDA approval of Italfarmaco’s Duvyzat is the first nonsteroidal drug to pass the agency’s regulatory bar for treating this rare disease.

Side effects

Side effects FDA Patients Biopharma

GSK to Gain Chronic Cough Drug With $2B Buyout of Bellus Health

MedCity News

APRIL 18, 2023

Acquiring Bellus Health gives GSK a drug for recurrent chronic cough that could offer a better side effect profile compared to a Merck drug that addresses the same target. Bayer was also pursuing the target, but stopped work on its drug candidate last year.

Side effects

Side effects Biopharma Pharma

Merck’s $1.3B Imago Buyout Brings Blood Cancer Drug to Rival BMS, Incyte & GSK

MedCity News

NOVEMBER 21, 2022

The deal gives the pharmaceutical giant a small molecule that could provide an alternative to a class of drugs that introduce dangerous side effects. Merck is acquiring Imago BioSciences, a clinical-stage biotech whose lead drug is in development for myelofibrosis and other blood cancers.

Side effects

Side effects Leads Pharmaceutical Biopharma

CNS-Focused Rapport Therapeutics Preps IPO to Back Phase 2-Ready Epilepsy Drug

MedCity News

MAY 19, 2024

Rapport Therapeutics’ lead program could offer more targeted epilepsy treatment compared to currently available anti-seizure medications, which introduce many side effects. The IPO will support plans to develop the oral small molecule in focal epilepsy as well as chronic pain and bipolar disorder.

Side effects

Side effects Leads Medical Biopharma

AbbVie Expands Psychiatric Drug Prospects, Inking R&D Pact With Neuroscience Startup

MedCity News

MAY 14, 2024

The companies aim to bring patients drugs that offer the benefit of psychedelics but with a better side effect profile. AbbVie’s alliance with Gilgamesh Pharmaceuticals is pursuing next-generation psychiatric medications.

Prospecting

Prospecting Side effects Pharmaceutical Medical

$5 billion bispecific antibody pharma collaboration

European Pharmaceutical Review

DECEMBER 7, 2022

Biopharma Akeso Inc. state the therapy could help reduce side effects and safety concerns. The post $5 billion bispecific antibody pharma collaboration appeared first on European Pharmaceutical Review. has announced it will enter into a collaboration potentially worth up to $5 billion with Summit Therapeutics Inc.,

Pharma

Pharma Side effects Safety Patients

Myovant Sciences rejects $2.5bn takeover bid from Sumitomo Pharma

Pharmaceutical Technology

OCTOBER 13, 2022

Myovant Sciences has rejected an acquisition offer from Sumitovant Biopharma and its wholly owned subsidiary, Sumitomo Pharma. The post Myovant Sciences rejects $2.5bn takeover bid from Sumitomo Pharma appeared first on Pharmaceutical Technology.

Food and Drug Administration

Food and Drug Administration Pharma Side effects FDA

Leading speciality pharmacies in pharma

Pharmaceutical Technology

SEPTEMBER 8, 2022

Speciality pharmacies play a crucial role in medication dosing, disease and side effects management, and patient care. Pharmaceutical Technology has listed the top speciality pharmacies in pharma based on its intel, insights, and decades of experience in the sector. Discover the top speciality pharmacies.

Specialization

Specialization Leads Pharma Side effects

Roche takes another punt on IL-2 in cancer with Good takeover

pharmaphorum

SEPTEMBER 7, 2022

The Swiss pharma group has agreed to buy Seattle-based biotech Good Therapeutics and its preclinical-stage PD-1-regulated IL-2 receptor agonist programme for $250 million upfront, with undisclosed milestone payments on offer tied to development, regulatory, and commercial objectives. billion.

Side effects

Side effects Biopharma Engineering Pharma

Practical advice for Early Scientific Advice (ESA) in HTA submissions

pharmaphorum

SEPTEMBER 28, 2022

In recent years, the biopharma market has become progressively complex. Payers must take into consideration not only the clinical efficacy of a drug, but also its safety profile, side effects, and cost-effectiveness, among other factors.

Biopharma

Biopharma Side effects Consulting Pharmaceutical products

FOCUS ON – Crowdsource/Adherence and Compliance

PM360

OCTOBER 22, 2024

DANNY SIGURDSON CEO and Founder Courier Health To effectively engage patients and prescribers to improve overall adherence to prescribed medication regimens, biopharma companies first need the visibility and full context of where a patient stands in their treatment journey. Patients’ challenges are diverse.

Education

Education Side effects Medical Patients

AUTHENTIC PATIENT VOICE: BOT TO TROT AI Steps Up to Transform Healthcare

PM360

JUNE 24, 2024

As we enter into the age of precision medicine, AI will be a critical tool to determine, with the help of disease knowledge graphs, which indications, associations, contraindications, side effects, genetic markers, drug targets, drug carriers, and interactions to take into account on a case-by-case basis.

Healthcare

Healthcare Healthcare Patients Side effects

How to Work with Patient Advocates, Influencers, and Ambassadors

PM360

JUNE 11, 2022

Only 5% of patients ranked pharma companies as the most trusted player in the healthcare space, according to a 2021 survey of 500 patients from Accenture. Patients want to know other patients are involved in what pharma is doing. Learn how pharma is involving them. They want to hear about those patients’ experiences.

Patients

Patients Pharma Education Media

Regulators and HTAs tune in to patient preference data

Clarivate

JUNE 26, 2023

Preference data can also be used to help make strategic decisions internally — for example, knowing patient preferences for the mode of administration or avoidance of side effects may help with clinical trial endpoint selection or product development.

Food and Drug Administration

Food and Drug Administration Patients Side effects Medicine

Novartis warns of two patients deaths after dosing with gene therapy Zolgensma

MedCity News

AUGUST 12, 2022

Liver complications are a known side effect risk of Zolgensma and other genetic medicines that are delivered by engineered viruses. The two deaths reported following treatment with Novartis’s Zolgensma mark the first fatal cases of acute liver failure associated with the gene therapy.

Side effects

Side effects Engineering Patients Medicine

Pharma Fix: The quest for the next tuberculosis vaccine

Pharmaceutical Technology

MARCH 24, 2023

Fox says adjuvant protein subunit vaccines can be a safer approach compared to live attenuated virus vaccines as there is a minimized risk of developing side effects. GC Biopharma is also running a Phase III trial for its live-attenuated vaccine GC-3107A to replace BCG.

Pharma

Pharma Side effects Marketing Biopharma

Pharma Rep Focus

Oral Metabolic Drug Acquired by Novo Nordisk Continues to Show Concerning Neuro Side Effects

Side Effects are Limiting GLP-1 Drug Efficacy: How Can Personalization Offer a Solution?

Trending Sources

Serious Side Effect Sidelines Gene-Edited Sickle Cell Therapy from Graphite Bio

Can Herbal Alternatives Ease the Economic Burden of Weight Loss Drugs?

FDA Nod in Duchenne Helps Wider Swath of Patients With the Rare Muscle Disease

GSK to Gain Chronic Cough Drug With $2B Buyout of Bellus Health

Merck’s $1.3B Imago Buyout Brings Blood Cancer Drug to Rival BMS, Incyte & GSK

CNS-Focused Rapport Therapeutics Preps IPO to Back Phase 2-Ready Epilepsy Drug

AbbVie Expands Psychiatric Drug Prospects, Inking R&D Pact With Neuroscience Startup

$5 billion bispecific antibody pharma collaboration

Myovant Sciences rejects $2.5bn takeover bid from Sumitomo Pharma

Leading speciality pharmacies in pharma

Roche takes another punt on IL-2 in cancer with Good takeover

Practical advice for Early Scientific Advice (ESA) in HTA submissions

FOCUS ON – Crowdsource/Adherence and Compliance

AUTHENTIC PATIENT VOICE: BOT TO TROT AI Steps Up to Transform Healthcare

How to Work with Patient Advocates, Influencers, and Ambassadors

Regulators and HTAs tune in to patient preference data

Novartis warns of two patients deaths after dosing with gene therapy Zolgensma

Pharma Fix: The quest for the next tuberculosis vaccine

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