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Madrigal sees road to approval for NASH drug resmetirom

pharmaphorum

That’s impressive, as it has proved exceedingly difficult for pharmacological therapies to show an impact on fibrosis in prior studies. Similarly, a one-stage or greater improvement in liver fibrosis was seen in 24% and 26% of the resmetirom groups, respectively, versus 14% of patients taking placebo.

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Leading innovators in pyridine derivatives for the pharmaceutical industry

Pharmaceutical Technology

Pyridine derivatives contain one nitrogen atom in a six-membered aromatic ring and are the most extensively used heterocycles in the field of drug design, due to their promising effect on pharmacological activity, which has led to the discovery of numerous broad-spectrum therapeutic agents.

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Beyond animal testing: the rise of organs-on-chips technology

Clarivate

Food and Administration (FDA) approval, a change long sought by animal welfare organizations. They became integral to physiological and pharmacological research during the 19th century and started to be systematically used for drug development during the 20th century. Clinical Pharmacology and Therapeutics, 104(6), pp.

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Sunshine Biopharma signs licence deal for Covid-19 treatment

Pharmaceutical Technology

Sunshine Biopharma has signed an exclusive global licence deal with the University of Arizona for PLpro-based Covid-19 treatment. Since February last year, Sunshine Biopharma has been working along with the University of Arizona on this project. Early R&D projects coverage on Pharmaceutical Technology is supported by Mimotopes.