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Ipsen beefs up in oncology, buying US biopharma Epizyme

pharmaphorum

per share for Cambridge, Massachusetts-based Epizyme – valuing the US company at around $247 million – and is also promising a further contingent value right (CVR) payment of up to $1 per share if Tazverik (tazemetostat) achieves certain development and sales targets. Ipsen is offering $1.45 Ipsen’s CVR offer includes $0.30

Biopharma 110
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CD19 CAR-T agents to boost blood cancer market

European Pharmaceutical Review

GlobalData predicts Bristol-Myers Squibb’s Breyanzi and Gilead’s Yescarta are set to have high annual sales in the forecast period. The number of blood cancer patients receiving CD19-directed CAR-T therapies is set to boom over the next decade from approximately 3,700 patients in 2021 to nearly 13,500 patients in 2031.

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High risk, high reward – the future of CAR-T therapy in CLL

Pharmaceutical Technology

In 2010, two patients with end-stage refractory chronic lymphocytic leukaemia (CLL) were administered Novartis’ autologous anti-CD19 chimeric antigen receptor T-cell (CAR-T) therapy, Kymriah (tisagenlecleucel), as part of a Phase I trial.

Patients 111
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Could obicetrapib facilitate sufficient LDL-cholesterol levels?

European Pharmaceutical Review

Clinical benefits seen in the obicetrapib Phase II ROSE2 trial In the Phase II ROSE2 trial, patients received a combination therapy of 10mg of obicetrapib or placebo for 12 weeks. LDL-C levels were observed to lower in 88 percent of patients to less than 55mg/dL. The treatment is expected to launch in 2028 in the US, EU, and Japan.

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What Is Pharma Marketing in 2025?

PM360

Unlike previous years where five to seven trends were examined, the 2025 report narrowed its focus to three that matter most and will make the most impact across the pharma landscape this year: applied AI, the Direct-to-Patient (DTP) model, as well as globalization and health equity. But the extent to which brands still have U.S.

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Medical Sales Opportunities for the Next Decade

Every Ancillary

Most seasoned medical sales representatives have carried several different products or services over their careers. Between emerging technologies, expiring patents, and ever-changing insurance coverage, the role of a medical sales professional is to constantly adapt and learn new things. Patient compliance can be an issue.

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Oncology biosimilar case studies: rituximab biosimilars

Pharmaceutical Technology

Rituxan received its first FDA approval in 1997 for the treatment of B-cell non-Hodgkin’s lymphoma (B-NHL) and reached peak global sales of $7.5bn in 2014. Rituximab biosimilars have since achieved notable commercial success, with global sales surpassing $900m collectively.

Sales 59