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A draft joint EU network strategy to 2028 has been published by the European Medicines Agency (EMA) and the Heads of Medicines Agencies (HMA). The overarching theme of our updated strategy to 2028 is that of change – rapid, somewhat unpredictable but nonetheless full of promise.
Despite this, Spikevax’s average annual sales forecast has plummeted by 23% between H1 and H2 2022 according to GlobalData’s Coronavirus Disease 2019 (COVID-19) Sector Forecast reports, due to increasing competition from Pfizer’s Comirnaty, Novavax’s Nuvaxovid, and Covid-19 therapeutics.
Pharma has gone to court again and again to delay generic competition of biologic drugs. One company AbbVie has used the courts to stop competition of its top drug Humira. Another biologic, Enbrel, on the market since 1998, will not have its $5 billion in sales challenged until the end of 2028.
According to GlobalData’s report, Paxlovid, the company’s small-molecule Covid-19 oral therapy, was shown to reduce Covid-19 infections by 32% in adults and is forecast to be the top-selling drug by total sales, generating $81bn between 2021 and 2028. AbbVie reported a 22.7% Bristol Myers Squibb (BMS) documented a 9.1%
Without sufficient support systems and experienced reviewers, the implementation timelines were extended, with final compliance dates now pushed to December 2028 (from May 2024 originally). This situation raises concerns that similar delays could impact the EU AI Act, creating uncertainty for companies relying on clear, consistent timelines.
Ultimately, this puts European businesses at a competitive disadvantage compared to other companies worldwide. Once adopted by the Council, the regulatory proposals are planned to come into force on 1 July 2028 (for BEFIT) and on 1 January 2026 (for the transfer pricing proposal).
The deal comes as Amgen has been under pressure from competition to its big-selling arthritis therapy Enbrel (etanercept) and blood cell booster Epogen (epoetin alfa), and a patent expiry for psoriasis blockbuster Otezla (apremilast) in 2028.
Now, Roche has an opportunity to add ease of administration to the competitive profile of Tecentriq, reducing the time patients have to spend in clinics and potentially reducing the cost of treatment. Results from a trial in first-line NSCLC are due in early 2023.
These are forecast to generate $264 billion in sales between 2021 and 2028. The forecast across the seven years between 2022 and 2028 saw an average decline of 7%, resulting in a $10 billion drop in the total forecast sales between 2021 and 2028. Likewise, Moderna’s Spikevax, the second leading COVID-19 vaccine with 19.5
They do not have biosimilar or generic competition available in the market. Additionally, highly competitive classes, such as rapid-acting insulin and immunologics are included on the selected drug list. They do not qualify for any exemption (e.g., for orphan products or plasma therapies).
billion sales globally by 2029, this could offset Keytruda’s decline sales expected after its loss of exclusivity in 2028, GlobalData highlighted. This is mainly due to the reported decline in sales of Humira, a consequence of biosimilar competition. With the company’s monoclonal antibody drug candidate PRA023 predicted to reach $2.1
It also means that employers face the most competitive, candidate-driven employment market in history. jobs by 2028 , there should be an even bigger shortfall between the number of open jobs and available workers. In sum, we expect sales hiring in 2020 to continue its torrid pace which means great times ahead for sales professionals.
The use of medicines worldwide grew by 14% over the past five years, and is expected to grow an additional 12% by 2028. Navigating global regulations shouldnt be seen as a hurdle; its a competitive advantage for the brands that do it well. More patients are being treated with better medicines as healthcare infrastructures improve.
However, in the second year of biosimilar competition, Rituxan sales started to significantly erode. However, there is also competition with subcutaneous branded rituximab, which cannibalises Rituxan and complicates this assumption.
Attention deficit hyperactivity disorder (ADHD) drug Vyvanse (lisdexamfetamine dimesylate) , manufactured by Takeda, also is facing generic competition. In the respiratory area with inhalers, it’s tough to get drugs approved, so the competition comes slowly,” he said. Starting in 2026, the provision will affect 10 Part D drugs.
This growth is expected to continue, with a 62% growth in annual consensus sales forecast from 2023 to 2028, fuelled by the company’s semaglutide portfolio, according to GlobalData’s report, ‘Looking ahead to 2023 – the future of pharma’. Novo Nordisk reported an 18.2% Sanofi and Regeneron’s market capitalisation grew by 12.4%
million by 2028. The potential increase in industry competition could also spell trouble for some. Now, the demand for such equipment is on track to grow exponentially. For instance, experts estimate that the global disposable spinal instruments market will grow at a CAGR of 8.3%, reaching a valuation of $96.5
billion and $812 million in 2028. Competition in an increasingly heated market. Vaxcyte’s recent clinical success brings further competition into a sector, which is becoming increasingly heated. VAX-24 has forecasted sales of $21 million in the same year. Further plans in the making.
Keytruda is due to lose patent protection in around 2028, and the threat of generic competition to it and other top sellers like type 2 diabetes therapy Januvia (sitagliptin) gives it one of the steeper patent cliffs among to-tier pharma groups.
NEWS: Biopharma struggling to find talent with adequate digital skills Looking onward to 2028, the Skills report predicted that, out of a total 81 percent within the cell and gene therapy industry, roles will span support services, R&D and discovery, and bioprocessing.
These high prices are the result of multiple factors: theyre derived from living organisms making them sensitive and complex for both manufacturers and patients, research requires advanced technology to test for safety and effectiveness, and theyre in high demand without much competition. Starting in 2019, the US market was valued at $4.5
By this same virtue, PROTACs are able to degrade previously undruggable targets, which provides a major competitive advantage for this modality if shown to be true. GlobalData’s analyst consensus forecast database estimates peak annual sales for ARV-110 of $325 million in 2028.
The dearth of cancer drugs (only blood cancer drug Imbruvica made this first list) stems from CMS only pursuing negotiations for Part D drugs in 2026 and 2027, then expanding to Part B drugs in 2028. exclusions exist for orphan drug designation and biosimilar competition ).
Cons: Highly competitive with new options continually emerging. That being said, the clinical laboratory market is expected to see growth of nearly 40% by 2028. Pros: A growing market means a good chance for long-term success with each client. Mostly cash-pay, which means dependable, fast commissions. Opportunities: Liquid Amnion.
In our September 2023 report on the electrophysiology market, Clarivate projected that by 2028, PFA would represent 50% of the U.S. FDA approval in the fourth quarter, with Johnson & Johnson’s Varipulse system close behind, so competition will pick up. ablation market and would have a total global market value of $3 billion.
Pharma M&A activity was muted in 2022, coming in at its lowest level since 2013 – something of a surprise, given the looming patent cliff and pharma’s past reliance on M&A and biopartnering as a quick fix for revenues lost to generics and biosimilars competition. Of the biggest spenders in 2022, Merck/MSD opened its wallet the widest.
million by 2028. The potential increase in industry competition could also spell trouble for some. Now, the demand for such equipment is on track to grow exponentially. For instance, experts estimate that the global disposable spinal instruments market will grow at a CAGR of 8.3%, reaching a valuation of $96.5
However, a delicate balance will need to be struck between the need for affordable and accessible medicinal products and the desire to foster innovation and competitiveness in the EU. of the MDR and Article 110.4 of the IVDR for medical devices and in vitro diagnostic medical devices (IVDs).
billion by 2028. That means competition is fierce, especially in high-growth locations. The industry grew by 2.7% annually from 2015 to 2020 and is expected to reach $32.14 But it’s not all rainbows and sunshine… There are currently 37,340 roofing companies in the United States , a 1.2% increase from last year.
Although the dynamics within each therapeutic area may vary, certain archetypes could influence competitive dynamics. In this type of class, selecting one product could materially disrupt competitive dynamics. Competitive and pricing dynamics will vary based on the nuances associated with each therapeutic area.
The district court had previously blocked Sandoz and Zydus from producing, selling, offering to sell, or importing generic versions of Otezla until February 2028. This is one of several patent infringement cases Amgen has pursued in recent years to stave competition. billion worth of the drug worldwide. Patent No.
DICE currently has two oral IL-17 inhibitors in clinical development; DC-806 is in Phase II trials for plaque psoriasis treatment, and DC-856 is in a Phase I for psoriasis.Acquiring these treatments could pave the way for Lilly to enter the highly competitive psoriasis market , where AbbVie, Pfizer and Johnson & Johnson have already clashed.
As it stands, GlobalData analysis predicts that Keytruda’s yearly revenue will hit almost $35bn in 2028, up from $21bn in 2022. As the COVID-19 pandemic continues to take its toll on businesses worldwide, it’s time to look for new ways to create value, prepare for the future, and remain competitive in the ever-changing landscape.
In 2026, CMS will select up to 15 additional Part B or Part D drugs for negotiations that take effect in 2028, and up to 20 additional drugs every year thereafter (Part B covers physician-administered drugs, including infusions of complex biologics). In highly competitive categories like diabetes, net price could be half of the list price.
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