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Jazz Pharma uses flying pig for huge grey area DTC

World of DTC Marketing

billion by 2026. Given that most obstructive sleep apnea patients are obese men, it’s dangerous that the side effects listed for Sunosi say, “tell your doctor if you have heart problems, high blood pressure, kidney problems, diabetes, or high cholesterol.”

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BMS strikes $14bn deal for Karuna Therapeutics

European Pharmaceutical Review

It has demonstrated improvements in cognition and is not associated with common side effects of currently approved treatments like weight gain. Registrational clinical trials are currently underway evaluating KarXT for the treatment of Alzheimer’s disease psychosis, with data expected in 2026.

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Sanofi looks east with €300m Innovent cancer alliance

pharmaphorum

SAR444245, meanwhile, is a long-acting IL-2 that blocks off part of the molecule that engages with alpha receptors, designed to maintain the anticancer efficacy of the molecule while preventing side effects. It is being tested in a wide range of solid tumours and lymphoma, alone and in combination with other drugs.

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Key Developments from AMCP 2023 on Blockbuster Generics, Diabetes Drugs, PBM Legislation, and More

PM360

A generic here will improve access in OAB to a product with less side effects, which is especially important in the elderly population, Casberg noted. Starting in 2026, the provision will affect 10 Part D drugs. Overactive bladder (OAB) is the final category primped for significant generic competition in 2023, Casberg said.

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FDA makes moves to advance ALS research ahead of upcoming Amylyx AdCom

Pharmaceutical Technology

The Act authorizes the appropriation of $100,000,000 per fiscal year from 2022 to 2026. Sanofi's Rilutek, which has generic versions available, has shown a 35% survival benefit in stage 4 ALS, but the drug has several side effects which affect the patient’s quality of life. The FDA’s action plan.

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NewAmsterdam goes public to advance drug in abandoned class

pharmaphorum

That will fund operations until 2026, beyond the readout of phase 3 trials including the BROADWAY study of obicetrapib in adults with heterozygous familial hypercholesterolaemia (HeFH) and/or established atherosclerotic cardiovascular disease (ASCVD) who can’t control LDL cholesterol on statin drugs alone.