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billion by 2026. Given that most obstructive sleep apnea patients are obese men, it’s dangerous that the sideeffects listed for Sunosi say, “tell your doctor if you have heart problems, high blood pressure, kidney problems, diabetes, or high cholesterol.”
It has demonstrated improvements in cognition and is not associated with common sideeffects of currently approved treatments like weight gain. Currently under review by the US Food and Drug Administration (FDA), KarXT is expected to launch in the US in late 2024.
SAR444245, meanwhile, is a long-acting IL-2 that blocks off part of the molecule that engages with alpha receptors, designed to maintain the anticancer efficacy of the molecule while preventing sideeffects. It is being tested in a wide range of solid tumours and lymphoma, alone and in combination with other drugs.
A generic here will improve access in OAB to a product with less sideeffects, which is especially important in the elderly population, Casberg noted. In March, the FDA approved several new naloxone products using the pathway, including one from Amphastar, which will compete with other intranasal on the market.
In the lead-up to a critical meeting that will influence the approval of a new drug for amyotrophic lateral sclerosis (ALS), the US Food and Drug Administration (FDA) has detailed its plans to advance rare neurodegenerative disease research. The Act authorizes the appropriation of $100,000,000 per fiscal year from 2022 to 2026.
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