European Pharmaceutical Review

OCTOBER 7, 2022

This is especially beneficial as a way of decreasing potential side effects. Tablets were noted to be the most common form of OSD in 2021 because of their convenience and simplicity in production, transportation and delivery to the end user. Leading companies in the oral solid dosage market are Catalent, Inc.,

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Pharmaceutical Technology

NOVEMBER 14, 2022

Such developments, including a 2021 approval of AstraZeneca’s Saphnelo (anifrolumab) , prompted The Lancet Rheumatology to posit that 2022 could be a “banner year” for the condition. Saphnelo is also being studied in a Phase III trial in lupus nephritis, where a person’s immune system targets the kidneys, eventually leading to kidney failure.

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PM360

JUNE 29, 2022

Despite a slew of prescription options and widespread advertising pushes, most patients are sticking with over-the-counter (OTC) remedies rather than trying new preventive medications, according to Phreesia Life Sciences’ survey results collected from more than 4,000 patients checking in for their doctors’ appointments in July 2021.

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PM360

MAY 25, 2023

adults experienced mental illness in 2021, which represents about 1 in 5 adults or 57.8 They’re wonderful medications, blockbuster sales, but real side effects. I think the best way is to come up with alternatives that don’t have these side effects, because then the problem is solved. million people.

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European Pharmaceutical Review

JUNE 12, 2024

This randomised, open label-controlled multicentre clinical trial was conducted across 21 sites in Spain from 2021 to 2023. The specific representation of these events differed between the treatments, highlighting potential differences in side effect profiles that should be explored in further studies. 2021; 27 (2): S1-S21.

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LEVO Health

JULY 15, 2024

In 2021, the GLP-1 market was valued at $16.53 Given their effectiveness, GLP-1 medications have gained popularity, leading to a surge in market demand. Here’s how: Enhance Patient Engagement Engaging patients effectively is key to building a successful GLP-1 program. billion and is projected to reach $24.10

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pharmaphorum

JULY 19, 2022

China’s Simcere Pharmaceutical has been granted approval in its home market for Cosela, a drug designed to limit the side effects of cancer chemotherapy, partnered with US biotech G1 Therapeutics. It is also being tested in phase 3 trials involving patients with advanced colorectal cancer and triple-negative breast cancer (TNBC).

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Medico Reach

AUGUST 25, 2022

Financial markets around the world saw the peak of Biotech indices in 2021. Where June 2021 saw nearly 45 Biotech startups going public, June 2022 stared at an almost stagnant number of 14. Almost 80% of startups that went public in 2021 traded below their initial offering price in 2022. Biotechnology Marketing Specifications.

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pharmaphorum

DECEMBER 13, 2022

Krazati has been cleared as a treatment for patients with KRASG12C-mutated non-small cell lung cancer (NSCLC) after one prior systemic therapy – the same indication given to Amgen’s Lumakras (sotorasib) when it became the first KRAS inhibitor to be approved in the US in May 2021.

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European Pharmaceutical Review

OCTOBER 19, 2023

Can you share an update on the clinical trial for your lead candidate? One aspect that is extremely promising about radiopharmaceutical therapeutics is that they do not give a patient the side effects that are commonly experienced with chemotherapy.

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PM360

AUGUST 26, 2024

Between 2015 and 2021, over a quarter of the drugs approved by the US Food and Drug Administration (FDA) were associated with specific biomarkers. Cancer detection involves measurement of biomarkers, which leads to the application of targeted therapy (which targets specific cancer cells). Let’s take cancer for example.

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Clarivate

JANUARY 3, 2023

Starting with 12,160 Research Fronts, representing papers published and cited between 2016 and 2021, the next step was to select the fronts containing core literature that is both highly cited and recent – an indicator of particularly active and fast-moving research. Fields and nations.

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PM360

AUGUST 9, 2022

1 It is by far the leading contributor to preventable healthcare costs in the United States, generating $300–528.4 Indeed, in research from the 2021 PURE Report, 3 50% of the patients responding found the therapy discussion to be a highly stressful period in their treatment journey. Up to 10% of hospital admissions in the U.S.

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European Pharmaceutical Review

NOVEMBER 4, 2022

based treatment concomitant with reductions in traditionally unavoidable and problematic side effects. 2021 [cited 12 September 2022]. FDA Feedback Leads to Discontinuation of Tesetaxel Development in Solid Tumors [Internet]. The importance of taxanes in oncology. Oncology Nursing News. Available from: [link]. Pfizer Inc.

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European Pharmaceutical Review

JULY 5, 2022

There is an urgent need for more effective chemotherapy treatments with less severe toxicity and side effects. Irinotecan – also known by the brand name Campto/Camptosar ® (Pfizer Ltd.) – has proven to be an effective chemotherapy agent against several types of gastrointestinal cancer.

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Pharmaceutical Technology

JANUARY 30, 2023

The FDA approved fewer innovative drugs, New Molecular Entities (NMEs), in 2022 than it did in 2021: only 42 drugs compared to 59 drugs. Aduhelm is both costly and commonly produces side effects. This is due to generally more stringent criteria on approvals in the wake of the Aduhelm scandal. months longer on the treatment.

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Pharmaceutical Technology

AUGUST 26, 2022

The potential potency of the two regimens could lead to the development of shorter TB treatment that would be accessible for drug-resistant and drug-susceptible patients, he adds. In 2021, the Foundation for the National Institute of Health (FNIH) began assisting PAN-TB’s efforts through project management of the PAN-TB governance bodies.

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Impetus Digital

AUGUST 2, 2024

Unsurprisingly, the US FDA has reported a noticeable increase in the number of submissions that use AI/machine learning (ML) components in recent years; in 2021, they received more than 100 submissions wherein AI use was reported. In 2022, the AI-fuelled pipeline reportedly expanded at an annual rate of almost 40%.

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Pharmaceutical Representative Training

OCTOBER 9, 2024

3 By actively listening to providers and addressing their objections with tailored solutions, sales professionals can cultivate strong relationships that lead to success in this competitive field. They may have valid concerns about the product’s cost, potential side effects, or its suitability for their patients.

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Pharmaceutical Technology

JANUARY 25, 2023

By selectively degrading these proteins, PROTACs have the potential to effectively treat a range of diseases with potentially fewer side effects compared to traditional approaches. According to Syngene: “Although PROTACs are considered revolutionary, to date, the design and optimization of PROTACs remain empirical.

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Pharmaceutical Technology

NOVEMBER 1, 2022

Israel, another leading adopter, has a thriving EHR technology industry that is adapting to the country’s widespread use of Big Data from its country’s healthcare systems. intervention) was the “cause” of an effect. These studies are often done to understand the side effects of different therapies.

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PM360

JULY 13, 2023

Launched in 2021, Adheris Health’s intelligent patient platform, THRiV, translates these patient insights into actions. com An estimated 50% of patients with a prescription for a chronic condition stop taking it within the first year, leading to worse outcomes and nearly $250 billion lost revenue annually for the pharmaceutical industry.

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European Pharmaceutical Review

SEPTEMBER 22, 2023

Targeting toxic species of Abeta, such as multimers (with aducanumab and lecanemab) or pyroglutamate Abeta3-42 (with donanemab), induced significant removal of Abeta plaque load in the brains of Alzheimer’s patients, leading to the delay in cognitive decline. Treatment with the mAbs delayed cognitive decline by 2.6 months for lecanemab and 5.5

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European Pharmaceutical Review

AUGUST 15, 2024

1 The cancer is a slow-growing but potentially life-threatening B-cell malignancy, in which increased activation of B-cell receptor signalling pathways leads to overgrowth of lymphocytes in bone marrow and other disease compartments. 2021; 39(31):3441–52. 2021; 8(12):e879–90. Byrd JC, Hillmen P, Ghia P, et al.

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European Pharmaceutical Review

AUGUST 3, 2023

Even then, there was a twenty-year gap between the authorisation of the last Alzheimer’s treatment and the 2021 authorisation of the anti-amyloid therapy Aduhlem (aducanumab) , also approved by the FDA as an accelerated marketing authorisation. However, if anything, that approval only served to increase doubts in anti-amyloid therapies.

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Pharmaceutical Technology

AUGUST 12, 2022

In the lead-up to a critical meeting that will influence the approval of a new drug for amyotrophic lateral sclerosis (ALS), the US Food and Drug Administration (FDA) has detailed its plans to advance rare neurodegenerative disease research. The other therapy Mitsubishi Tanabe Pharma’s Radicava is only effective in the early stages of ALS.

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PM360

AUGUST 9, 2022

According to the 2021 Accenture Healthcare Experience Survey, 52% of patients say having emotional support is important to having a positive healthcare experience. Accordingly, multiple reasons for subpar patient adherence are gaining attention, including fear of side effects, lack of medical understanding, or even financial limitations.

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European Pharmaceutical Review

JANUARY 25, 2024

They detail the medication’s intended use, proper administration, potential side effects and precautions. They are vital to ensuring the safe and effective use of medicines, making them an integral part of healthcare in Europe. Eurostat (2022) “How many citizens had basic digital skills in 2021?”

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European Pharmaceutical Review

AUGUST 24, 2022

Functionality of ADCs is dependent on being internalised together with the target into the endosomal/lysosomal compartment, where the cytotoxin is released by controllable chemistry leading to the death of the cancer cell. The culmination of two decades of learning.

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Clarivate

AUGUST 17, 2022

Inadequate health services can have devastating consequences, especially when it comes to non-communicable diseases (NCD) , such as cardiovascular diseases, cancers and diabetes, which is the leading cause of death globally. In December 2021, your company was acquired by Clarivate.

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European Pharmaceutical Review

AUGUST 30, 2022

Nasal delivery is non-invasive and provides a more targeted delivery than the systemic injectable approach, potentially offering a quicker response and reduced side effects. million by 2029, up from $122.287 million in 2021. Key to overcoming many of these challenges lies in the evolution of nasal spray device design.

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European Pharmaceutical Review

DECEMBER 27, 2023

Lessons learned The process of establishing point-of-care CAR T manufacturing was a learning curve, not just in managing the toxicities and side effects, but also in understanding the important difference between emerging CAR T-cell adoptive immunotherapy and traditional stem cell transplantation. Journal of Clinical Oncology.

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Healthcare Success

OCTOBER 17, 2024

Tune in to our latest podcast as Lee Aase, founder of HELPCare, LLC, shares how he transitioned from his pioneering social media work at Mayo Clinic to lead an innovative membership-based direct-to-patient healthcare business. I took early retirement from Mayo Clinic in August of 2021 to found a company called HELPCare, LLC.

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PM360

JUNE 11, 2022

Only 5% of patients ranked pharma companies as the most trusted player in the healthcare space, according to a 2021 survey of 500 patients from Accenture. A Patient-Centric Month Leads to Results. At Astellas, for example, June now is Patient Centricity Month each year.

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European Pharmaceutical Review

OCTOBER 3, 2024

Although effective, this approach often results in significant side effects, including increased susceptibility to viral reactivation, infections, and, in some cases, a heightened risk of cancer due to reduced immune surveillance. 2021; 46(46):101102. Available from: [link] Nauck MA, Quast DR, Wefers J, Meier JJ.

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Evolve Your Success

FEBRUARY 13, 2024

I was thankful and blessed to connect with one of the leading researchers on my subtype. At my age, he was like, “You had such a great response to chemo that you have a higher chance of dealing with major issues and potential fatality from radiation side effects in twenty years versus the cancer coming back.” He’s a great guy.

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Pharmaceutical Technology

FEBRUARY 17, 2023

In 2021, the FDA granted Amgen’s (NASDAQ:AMGN) non-small cell lung cancer (NSCLC) drug Lumakras (sotorasib) an expedited approval, making it the first FDA-approved KRAS inhibitor. The demand came amid concerns that the drug causes a slew of side effects such as nausea, diarrhea, and liver issues. What is drug dose optimisation?

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