pharmaphorum

JANUARY 3, 2023

A pharmacologist by training, Rawlins was the founding chairman of health technology assessment (HTA) agency NICE , leading the organisation from its inception in 1999 until 2013, and hired Sir Andrew Dillon to become the organisation’s founding chief executive.

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pharmaphorum

OCTOBER 24, 2022

The study bucked the trend of tremelimumab adding little or nothing when added to Imfinzi across a range of cancer types, whilst adding to the side-effect burden of therapy. Liver cancer is the third-leading cause of cancer death and the sixth most commonly diagnosed cancer worldwide.

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FDA Side effects Patients Leads 81

European Pharmaceutical Review

JANUARY 11, 2024

The current medications (opioid and non-opioid) often force the patients to make an unfortunate choice between efficacy and debilitating side effects, leading to a cycling through multiple different therapies and suboptimal treatment response. The present unmet needs within chronic pain are not met with opioid therapies.

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pharmaphorum

AUGUST 5, 2022

SAR444245, meanwhile, is a long-acting IL-2 that blocks off part of the molecule that engages with alpha receptors, designed to maintain the anticancer efficacy of the molecule while preventing side effects. It is being tested in a wide range of solid tumours and lymphoma, alone and in combination with other drugs.

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Pharmaceutical Technology

APRIL 14, 2023

Alongside increased liver fat, NASH patients suffer from liver inflammation and damage that can eventually lead to fibrosis. Liver fibrosis, also known as scarring, can lead to cirrhosis, and patients with cirrhosis can develop liver cancer. The American agency previously rejected the company’s NDA for obeticholic acid in June 2020.

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Pharmaceutical Representative Training

JUNE 22, 2024

Technological advancements, shifting market dynamics, and updated regulations are leading to significant changes within the pharmaceutical industry. Preventing Misuse: Strict regulations are required to stop the improper use and abuse of drugs, especially those that have strong side effects or the potential to become addictive.

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pharmaphorum

JULY 19, 2022

China’s Simcere Pharmaceutical has been granted approval in its home market for Cosela, a drug designed to limit the side effects of cancer chemotherapy, partnered with US biotech G1 Therapeutics. The Chinese company secured rights to Cosela in Greater China for $170 million in 2020.

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pharmaphorum

JUNE 23, 2022

It is a challenging proposition, however, as delivery of the therapeutic gene sequences to cells can be difficult and raises the risk of insertion mutations that can lead to side effects, including cancer. billion agreement that started in 2020.

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pharmaphorum

OCTOBER 1, 2022

The dive came despite Intercept’s despite assertions that it remains on track to resubmit the FXR agonist in its lead indication of fibrosis due to NASH by year end. It will now do so on the strength of the phase 3 REGENERATE study, which involved patients with liver fibrosis due to NASH, a less severely affected population.

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Side effects FDA Prospecting Pharma 59

pharmaphorum

JULY 13, 2022

However, they can lead to unwanted effects such as insertions, deletions, or other DNA rearrangements at the site of the break which raises the risk of side effects. Other CRISPR-based therapies generate a DSB at a precise location, after which cellular processes carry out the editing function.

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Side effects Medicine Patients Marketing 97

Pharmaceutical Technology

NOVEMBER 1, 2022

In a few weeks, the EU-funded research project Darwin EU will announce its first batch of data partners for the ambitious real-world data -driven Horizon 2020 project. Israel, another leading adopter, has a thriving EHR technology industry that is adapting to the country’s widespread use of Big Data from its country’s healthcare systems.

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PM360

AUGUST 26, 2024

During the period from 2008 through 2020, the number of precision medicines in the US increased from 5 to 285. Cancer detection involves measurement of biomarkers, which leads to the application of targeted therapy (which targets specific cancer cells). That’s how money is saved and quality of life (QOL) is improved.

Medicine 52

Medicine Food and Drug Administration Government Insurance 52

Medico Reach

FEBRUARY 8, 2023

billion in 2020 and will project growth of USD 4.18 billion during 2020-2024. AI can lead to faster research, combining and extracting data into usable formats, making clinical trials more efficient and saving time. The Emergence of the Pharmacovigilance Market Medicines and vaccines often have unwanted and severe side effects.

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Pharma Medicine Marketing Prospecting 52

Pharmaceutical Technology

AUGUST 26, 2022

The potential potency of the two regimens could lead to the development of shorter TB treatment that would be accessible for drug-resistant and drug-susceptible patients, he adds. The PAN-TB collaboration was created in 2020, to address the need for new novel treatment regimens for TB. Challenges of current TB treatment.

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Side effects Pharmaceutical Patients Recruitment 98

Impetus Digital

AUGUST 2, 2024

In theory, this will allow for highly tailored, personalized therapy plans with superior efficacy and minimal side effects. In turn, this can support decision-making and lead to more efficient inventory management and faster delivery times, enhance supply chain visibility and transparency, and avoid overproduction and waste.

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Pharma Manufacturing Medicine Marketing 95

pharmaphorum

JULY 26, 2022

CETP (cholesterol ester transfer protein) drugs are designed to lower levels of LDL cholesterol and apolipoprotein B and boost levels of protective HDL cholesterol, to reduce the likelihood of fatty plaques in arteries that can restrict blood flow and lead to heart attacks and strokes. Amgen licensed the rights to NewAmsterdam in 2020.

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Side effects Safety Pharma Patients 52

Pharmaceutical Technology

JANUARY 30, 2023

Aduhelm is both costly and commonly produces side effects. Spikevax was granted an Emergency Use Authorisation in 2020, and finally gained FDA market approval on 31 January 2022. The approval was based on claims that the drug led to a reduction in amyloid plaques in the brain. months longer on the treatment.

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Manufacturing FDA Side effects Marketing 52

European Pharmaceutical Review

SEPTEMBER 22, 2023

Targeting toxic species of Abeta, such as multimers (with aducanumab and lecanemab) or pyroglutamate Abeta3-42 (with donanemab), induced significant removal of Abeta plaque load in the brains of Alzheimer’s patients, leading to the delay in cognitive decline. Treatment with the mAbs delayed cognitive decline by 2.6 months for lecanemab and 5.5

Food and Drug Administration 97

Food and Drug Administration Safety Patients Leads 97

European Pharmaceutical Review

JANUARY 25, 2024

They detail the medication’s intended use, proper administration, potential side effects and precautions. They are vital to ensuring the safe and effective use of medicines, making them an integral part of healthcare in Europe. Article 63 EMA (29 January 2020).

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Healthcare Healthcare Safety Electronics 98

European Pharmaceutical Review

AUGUST 15, 2024

1 The cancer is a slow-growing but potentially life-threatening B-cell malignancy, in which increased activation of B-cell receptor signalling pathways leads to overgrowth of lymphocytes in bone marrow and other disease compartments. 2020; 21(9):1188–200. The Lancet Oncology. Kater AP, Owen C, Moreno C, et al. NEJM Evidence.

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Referral MD

JULY 10, 2023

They can also offer additional information, such as side effects, ensuring patients are well-informed about their prescriptions. Additionally, as technology advances, the capabilities of chatbots will likely expand, leading to even higher patient satisfaction.

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Patients Healthcare Healthcare Healthcare Provider 74

European Pharmaceutical Review

AUGUST 3, 2023

However, the EMA expressed concerns around overall efficacy and, coupled with a concern raised over possible side effects presenting as brain abnormalities suggestive of swelling or bleeding on the brain, led the EMA to the view, following a re-examination process, that it would not recommend the approval of Aduhelm. cited 2023Aug].

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European Pharmaceutical Review

NOVEMBER 4, 2022

based treatment concomitant with reductions in traditionally unavoidable and problematic side effects. In 2020, Athenex completed a Phase III trial in metastatic breast cancer comparing Oraxol to three-weekly (q3w) IV paclitaxel. FDA Feedback Leads to Discontinuation of Tesetaxel Development in Solid Tumors [Internet].

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Food and Drug Administration Pharmaceutical FDA Patients 98

Clarify Health

JULY 27, 2020

The panelists also discussed the impact the pandemic has had on ‘regular,’ non-COVID-19 care, clinical side effects of lockdown, and whether it is safe for patients to return to the doctor’s office. Could this be the example the industry needs to change the trajectory of adoption of other technologies?

Healthcare 52

Healthcare Healthcare Patients Safety 52

World of DTC Marketing

JUNE 21, 2021

According to the Ad Contrarian: Between January 2020 and October 2020, the percent of people who canceled a paid streaming service went from 20% to 46%. This leads to a big problem. Of course, some will point to the fact that people are moving to streaming services but that too is more hype than reality.

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Pharmaceutical Technology

NOVEMBER 30, 2022

In the past, obesity medications were often dismissed due to insufficient efficacy data and the fact that they were associated with a high occurrence of side effects. Novo Nordisk is another company leading the charge in this field. In the US, obesity care is estimated at to cost $147 billion in healthcare spending annually.

Medical 105

Medical Manufacturing Insurance Side effects 105

Pharmaceutical Technology

NOVEMBER 30, 2022

In the past, obesity medications were often dismissed due to insufficient efficacy data and the fact that they were associated with a high occurrence of side effects. Novo Nordisk is another company leading the charge in this field. In the US, obesity care is estimated at to cost $147 billion in healthcare spending annually.

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Medical Manufacturing Insurance Side effects 98

Pharmaceutical Technology

MARCH 24, 2023

Researchers expect TB to soon return to its pre-2020 position as the deadliest infectious disease globally. Fox says adjuvant protein subunit vaccines can be a safer approach compared to live attenuated virus vaccines as there is a minimized risk of developing side effects. million new cases reported worldwide.

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Pharma Side effects Marketing Biopharma 64

World of DTC Marketing

NOVEMBER 16, 2020

Assuming both Moderna & Pfizer vaccines are granted FDA Emergency Use Approval status, what’s going to happen when the media picks up on stories of severe side effects from those who receive the vaccine. People are tired of quarantining and wearing masks which in turn has lead to a relaxed atmosphere.

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Media Side effects Distribution Physicians 203