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New analysis sets stage for improved UK clinical trials

European Pharmaceutical Review

Key findings for UK clinical trials For clinical trials submitted between 2019 and 2023, highlights from the analysis showed that one in eight trials tested treatments in humans for the first time. Despite these advances, the analysis found that disparities in representation of patient populations.

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Can Hepatitis C drugs reduce symptoms of PTSD?

European Pharmaceutical Review

The researchers studied 254 VA patients who were diagnosed with PTSD and hepatitis C between October 1999 and September 2019. Patients’ symptoms were monitored for PTSD and hepatitis C virus between two clinical visits over eight to 12 weeks. MDMA-assisted therapy successful in PTSD patients.

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FDA suggests ways to curb constraints with rare disease gene therapy trials

Pharmaceutical Technology

On February 7, at a town hall organised to discuss clinical trial designs for gene therapies, FDA experts pushed pharma players to look for ways to establish clinical effectiveness despite the challenges in recruiting patients with rare diseases.

FDA 105
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Digital Self-Neuromodulation Therapy for PTSD: Interview with Oded Kraft, CEO of GrayMatters Health

Medgadget

The system uses the patient’s EEG data to calculate a value for the amygdala-derived-EFP biomarker, and meanwhile the patient tries various mental strategies that may help to reduce the value. These treatments at times come with a long list of side effects, leaving many patients in search of an effective long-term solution.

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Advancing AOCs to transform the delivery of RNA therapeutics

European Pharmaceutical Review

The first approved ASO was designed for injection directly into the eye for the local treatment of cytomegalovirus (CMV) retinitis in immunocompromised AIDS patients. Known linkers in the RNA field are used to bond together the two pharmacologically active molecular entities and can be applied to multiple oligonucleotide modalities.

Safety 98
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Pharmacodynamics and Pharmacokinetics: The Science Behind Drug Action (Understanding the different characteristics of a drug and how they are important for therapeutic success)

Pharmaceutical Representative Training

Imagine a patient who takes ibuprofen to treat a headache. A drugs solubility, how the liver metabolizes it, and patient-specific factors like genetics can influence the journey of a drug. These details are the reasons why knowledge of PK and PD is fundamental to making every drug both effective and safe for every patient.

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Miracor Medical Announces FDA IDE Approval For PiCSO® Pivotal Study

Legacy MEDSearch

The PiCSO-AMI-II multicenter, randomized trial will enroll 300 patients with anterior ST-segment Elevation Myocardial Infarction (STEMI) presenting with TIMI flow 0, 1, and 2 within 12 hours of symptom onset. PiCSO therapy is a promising new therapy to reduce infarct size and improve outcomes in anterior STEMI patients. said Prof.

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