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New analysis sets stage for improved UK clinical trials

European Pharmaceutical Review

Key findings for UK clinical trials For clinical trials submitted between 2019 and 2023, highlights from the analysis showed that one in eight trials tested treatments in humans for the first time.

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Can Hepatitis C drugs reduce symptoms of PTSD?

European Pharmaceutical Review

The researchers studied 254 VA patients who were diagnosed with PTSD and hepatitis C between October 1999 and September 2019. PTSD is a potentially chronic condition that disrupts lives and can lead to or exacerbate existing health issues such as depression, anxiety, eating disorders, and suicidal thoughts.

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FDA suggests ways to curb constraints with rare disease gene therapy trials

Pharmaceutical Technology

Blank acknowledged that in many cases, an exclusively paediatric patient population could lead to difficulties with drawing consent for early phase trials. Still, Blank suggested that companies enroll the patient population that is most likely to benefit, because early phase studies contain the most safety risks.

FDA 105
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Advancing AOCs to transform the delivery of RNA therapeutics

European Pharmaceutical Review

Known linkers in the RNA field are used to bond together the two pharmacologically active molecular entities and can be applied to multiple oligonucleotide modalities. Research advances are also helping us learn more about how RNA is processed, potentially leading to new strategies to alter dysfunctional RNA. 2019 ;42:385-406.

Safety 98
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Pharmacodynamics and Pharmacokinetics: The Science Behind Drug Action (Understanding the different characteristics of a drug and how they are important for therapeutic success)

Pharmaceutical Representative Training

Therapeutic drug monitoring is used to obtain peak and trough levels to determine drug serum concentration which tells us if a drug is efficacious or is leading to toxic levels. warfarin) which leads to higher plasma concentrations. Rang & Dale’s Pharmacology. The Pharmacological Basis of Therapeutics.

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Miracor Medical Announces FDA IDE Approval For PiCSO® Pivotal Study

Legacy MEDSearch

Early non-randomized European studies have suggested that this leads to reduced incidence of coronary microvascular obstruction (MVO) [3,4] and smaller infarct size, which are both strongly correlated to improvement in heart failure hospitalizations and reduced mortality following primary PCI [5]. About Miracor Medical.

Medical 52
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Embracing green innovation in life sciences

European Pharmaceutical Review

Research demonstrates that the greenest inhaler is the one that is used and that leads to disease control. If we want to lead the way in green innovation and show that the UK is open for business, we need a broader definition and recognition of innovation. Pulmonary Pharmacology & Therapeutics. 2024; 85: 1-9.