European Pharmaceutical Review

JUNE 12, 2024

Since 2018, biotech company Mikrobiomik has been researching, development and producing innovative biological medicines based on the human microbiome. The specific representation of these events differed between the treatments, highlighting potential differences in side effect profiles that should be explored in further studies.

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pharmaphorum

JUNE 24, 2022

If treatment is prompt and effective, patients can live a normal lifespan, but left untreated the disease can be fatal. Meanwhile, side effects are common and unpleasant with current treatment – including skin rash and blisters, vomiting and diarrhoea, and wounds that do not heal – so compliance an be poor.

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Pharmaceutical Technology

JULY 29, 2022

While the prevalence was 1 in 150 children in 2000, it reached the rate of 1 in 44 in 2018, in the US, according to the Centers for Disease Control and Prevention. The rate at which children are being identified with autism spectrum disorder (ASD) has tripled in the past two decades. Generic versions of both drugs are now available.

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Pharmaceutical Technology

NOVEMBER 1, 2022

In 2018, Israeli prime minister Benjamin Netanyahu put forth a $300 million initiative to support the country’s burgeoning data-driven healthcare system, allowing anonymised EHR data to be accessible to researchers and institutions to improve their healthcare solutions. intervention) was the “cause” of an effect.

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European Pharmaceutical Review

OCTOBER 19, 2023

The development of novel radiotherapeutics ushered in a new era in targeted treatment 1 for cancer, with two separate radiotherapeutic approvals in Europe and the US, in 2018 and 2022. Recent advancements for radiopharmaceuticals in oncology include a $1.4

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Food and Drug Administration Manufacturing Side effects Doctors 105

pharmaphorum

JULY 13, 2022

However, they can lead to unwanted effects such as insertions, deletions, or other DNA rearrangements at the site of the break which raises the risk of side effects. 2018: @VerveTx founded with concept of one-time Rx to lower LDL as low as possible for as long as possible. . Today: we are announcing.

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PM360

MARCH 24, 2023

Among polled patients who had never accessed a cancer-support program, education about cancer treatments and their side effects (33%), as well as information to help them better understand their cancer (32%) topped the list of resources they wished they had received. 24, 916–925 (2018). 43, 165–169 (2019). Stoerkel, E.

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Patients Education Side effects Media 98

pharmaphorum

SEPTEMBER 22, 2022

California biotech Calibr and partner AbbVie have reported the first clinical data on a new CAR-T technology, which uses “switchable” cells that aim to eliminate the life-threatening side-effects that can occur with this type of immunotherapy. Image source: Scripps Research Institute.

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pharmaphorum

JANUARY 6, 2023

Its stock price fell more than 4% percent, and the drugmaker suspended its Twitter advertising campaigns (among the more dramatic side effects of Twitter’s structural changes that jolted the pay-per-click advertising model). in 1979 to 2.8%in

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Prescription Manufacturing Patients Side effects 105

European Pharmaceutical Review

MAY 23, 2024

Imran joined Oncology US Medical Affairs in 2018 as the Therapeutic Area Lead, Lymphoma and Myeloid Malignances. CAR T-cell Therapy and its side effects [Internet]. About the interviewee Imran Khan, MD, PhD is Vice President Medical Affairs, Hematology at Johnson & Johnson Innovative Medicine. Medical Affairs. Cancer.gov.

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Food and Drug Administration Food Medical Medicine 110

European Pharmaceutical Review

JULY 5, 2022

There is an urgent need for more effective chemotherapy treatments with less severe toxicity and side effects. Irinotecan – also known by the brand name Campto/Camptosar ® (Pfizer Ltd.) – has proven to be an effective chemotherapy agent against several types of gastrointestinal cancer. About the author.

Patients 104

Patients Food and Drug Administration Side effects Safety 104

Pharmaceutical Technology

AUGUST 17, 2022

cases per 100,000 people in 2018. “In While there were concerns about Lymerix’s side effects, it was the low demand that led to its withdrawal, says Šíma, adding that VLA15 could be in a similar tough spot when it comes to its position on the market. In the UK, the mean annual incidence of Lyme disease grew from 0.38

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Medicine Side effects Marketing Recruitment 119

Pharmaceutical Technology

OCTOBER 13, 2022

Most currently available therapeutic options for endometriosis often have a diminished efficacy over time and result in negative side effects such as menopausal-like side effects and bone mineral density (BMD) loss. The approval of Myfembree marks a critical step forward in the endometriosis space.

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Food and Drug Administration Pharma Side effects FDA 52

Pharmaceutical Technology

NOVEMBER 3, 2022

Additionally, trial subjects did not have adverse movement or metabolic side effects usually seen with antipsychotic agents. Emalex was established in 2018 by Paragon Biosciences for developing new central nervous system (CNS) disorder treatments. In prior trials, the drug was found to be well tolerated. “Our

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Food and Drug Administration Side effects Food Patients 52

Pharmaceutical Technology

SEPTEMBER 26, 2022

It provides a further valuable treatment option that can increase the time they remain in good health and delay the need for chemotherapy and its associated side effects. “As In addition to palbociclib, NICE has granted approval for 15 other therapies for breast cancer since 2018.

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Side effects Medicine Pharmaceutical Patients 52

European Pharmaceutical Review

AUGUST 14, 2023

This data, together with a favourable safety profile, make C21 a potential game-changer for IPF patients, particularly those who are currently not treated due to the side effects of the available drugs, according to Dalsgaard.

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Pharma Side effects Patients Manufacturing 98

Clarivate

SEPTEMBER 25, 2024

A ‘magic bullet’ medicine that can cure a disease quickly and completely, [1] without deleterious side effects. [2] 6] As many pathogenetic targets have multiple physiological functions, highly specific ‘magic bullets’ may impact multiple cellular pathways simultaneously, causing unintended side effects.7

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pharmaphorum

SEPTEMBER 8, 2022

The problem with this form of treatment is that it is not targeted and, as a result, there are a number of short- and long-term side effects which can impact patients’ lives. billion acquisition of Endocyte in 2018 , with estimations that sales could reach $600 million in this first indication alone.

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Manufacturing Pharma Side effects Patients 105

European Pharmaceutical Review

DECEMBER 14, 2023

They enable a range of observational study designs to be used where researchers study a period of exposure to a particular medicine and compare it with a control period of non-exposure in the same patient to establish any changes in the risk of adverse side effects. 2018; 8(1). EMA/95098/2010.

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Medicine Safety Competition Medical 116

pharmaphorum

JULY 11, 2022

The company had been eyeing a possible regulatory filing for fitusiran this year, but has now set back the timeline – possibly until 2024 – while it gathers data on the revised dosing schedule, in the hope of maintaining efficacy with fewer clotting side effects. Sanofi acquired the drug when it bought Bioverativ in 2018 for $11.6

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PM360

AUGUST 9, 2022

The 2021 PURE report indicated that two out of three patients are concerned about potential side effects before taking their first dose, and again, this is more evident in women than men. May 23, 2018. Overall, more than 50% of patients also demonstrated high stress levels over financial and insurance considerations.

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Education Side effects Physicians Patients 59

European Pharmaceutical Review

AUGUST 24, 2022

The ultimate goal of the ADC concept is to maximise the potency of treatment and reduce unwanted side effects on healthy tissues. Prior to co-founding Tubulis in 2018, Dominik worked as a group leader at the Ludwig Maximillian University (LMU) in Munich. The culmination of two decades of learning.

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Engineering Side effects Marketing Patients 104

Pharmaceutical Technology

JANUARY 25, 2023

By selectively degrading these proteins, PROTACs have the potential to effectively treat a range of diseases with potentially fewer side effects compared to traditional approaches.

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Side effects Leads Safety Manufacturing 52

Pharmaceutical Technology

SEPTEMBER 23, 2022

Cisplatin has multiple side effects including loss of appetite, nausea, and ototoxicity (hearing loss). Despite the primary focus in cancer treatment being overall survival, there is a burgeoning interest in treating secondary effects, such as ototoxicity, which majorly affects the quality of life.

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FDA Patients Recruitment Side effects 52

PM360

OCTOBER 22, 2024

And with therapy underway, many of these programs help boost adherence¹ by addressing common barriers to compliance, like missed doses, side effects, and unreliable information about the drug and disease.² Published 2018 Jan 17. They promote access to therapy by helping eligible patients afford their medications. 2019.18443 2.

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Celeritas

NOVEMBER 21, 2022

They only partially impact the target areas and have damaging side effects in adjacent regions. Gold nanowires further positively impact key organ transplant functions – synapse formation and stem cell differentiation – all without using growth factors, which cause negative side effects.

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Engineering Transportation Side effects Networking 52

European Pharmaceutical Review

AUGUST 15, 2024

BTKis, oral drugs given as continuous monotherapy, have revolutionised the treatment of CLL, with the first generation BTKi ibrutinib receiving European Medicines Agency (EMA) approval in 2014; however, side-effects (such as cardiovascular toxicities 2 ) have limited its suitability. 2018; 378(12):1107–20. 2022; 36(4):1171–5.

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Safety Patients Medical Medicine 52

Pharmaceutical Technology

JANUARY 22, 2023

In 2022, the FDA approved only 37 new medicines, an underwhelming number compared to 98 in 2018. However, while only around 34% of the approvals in 2018 were for orphan drugs, 54% new approvals in 2022 were for drugs to treat rare diseases. rises/second (SD 0.0628) in the placebo group.

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FDA Safety Pharmaceutical Patients 126

Pharmaceutical Technology

NOVEMBER 30, 2022

A 2017–2018 National Health and Nutrition Examination Survey (NHANES), showed that 30.7% In the past, obesity medications were often dismissed due to insufficient efficacy data and the fact that they were associated with a high occurrence of side effects. The same can be said for the US. of adults were overweight, 42.4%

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Medical Manufacturing Insurance Side effects 105

Pharmaceutical Technology

NOVEMBER 30, 2022

A 2017–2018 National Health and Nutrition Examination Survey (NHANES), showed that 30.7% In the past, obesity medications were often dismissed due to insufficient efficacy data and the fact that they were associated with a high occurrence of side effects. The same can be said for the US. of adults were overweight, 42.4%

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Medical Manufacturing Insurance Side effects 98

Pharmaceutical Technology

MARCH 24, 2023

Fox says adjuvant protein subunit vaccines can be a safer approach compared to live attenuated virus vaccines as there is a minimized risk of developing side effects. Results from the Phase II trial were released for the vaccine in September 2018.

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Pharma Side effects Marketing Biopharma 64

World of DTC Marketing

FEBRUARY 23, 2021

How long do you believe it will be before the media once again runs stories about drug prices or drug side effects? The increase followed total Humira price hikes of 19 percent during 2017 and 2018, according to a survey by the nonprofit Institute for Clinical and Economic Review, which deemed the increases unjustified.

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Pharmaceutical Technology

MAY 31, 2023

The document would include the drug/biological product name, side effects, directions for use, safety information, and a concise summary of indications and uses. According to a 2018 study , nonadherence is especially an issue in the case of chronic illness where patients may be expected to take medications at least once daily.

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