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Progressing personalised cell therapies in oncology

European Pharmaceutical Review

About the interviewee Imran Khan, MD, PhD is Vice President Medical Affairs, Hematology at Johnson & Johnson Innovative Medicine. Most recently, Imran has served as Medical Science Liaison (MSL) Head, Oncology U.S. Medical Affairs. CAR T-cell Therapy and its side effects [Internet]. Cancer.gov.

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Targeted therapies for chronic lymphocytic leukaemia in an evolving treatment landscape

European Pharmaceutical Review

BTKis, oral drugs given as continuous monotherapy, have revolutionised the treatment of CLL, with the first generation BTKi ibrutinib receiving European Medicines Agency (EMA) approval in 2014; however, side-effects (such as cardiovascular toxicities 2 ) have limited its suitability. 2018; 378(12):1107–20. 2022; 36(4):1171–5.

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