European Pharmaceutical Review

JANUARY 11, 2024

The current medications (opioid and non-opioid) often force the patients to make an unfortunate choice between efficacy and debilitating side effects, leading to a cycling through multiple different therapies and suboptimal treatment response. 2017; 6(S1):1–3. Neuropathic pain: The scope of the problem. Pain and Therapy. Internet] NIH.

Medicine 102

Medicine Pharmacology Management Side effects 102

Pharmaceutical Technology

NOVEMBER 17, 2022

This marks the first update to NICE’s endometriosis guidelines since 2017, representing a huge milestone for patients and practitioners alike. This delay in diagnosis ultimately leads to disease progression and associated complications, such as chronic pelvic pain and infertility, which greatly affects the patients’ quality of life.

Management 102

Management Pharmacology Side effects Patients 102

Clarivate

SEPTEMBER 11, 2024

The pathophysiology of Alzheimer’s is complex and involves multiple mechanisms, including extracellular deposition of amyloid-β (Aβ) plaques and intracellular formation of neurofibrillary tangles (NFT) of tau, causing progressive neuronal loss and atrophy (Counts, 2017). Abbreviations: AD, Alzheimer’s disease; MCI, mild cognitive impairment.

Food and Drug Administration 59

Food and Drug Administration Pharmacology Food FDA 59

pharmaphorum

OCTOBER 25, 2022

The eyedrop formulation of UNR844 (lipoic acid/choline ester chloride) was acquired as part of the group’s buyout of privately-held ophthalmology biotech Encore Vision for $375 million upfront in 2017, and was designed to work by restoring the elasticity of the eye’s lens that declines with age.

Pharmacology 112

Pharmacology Pharma FDA Sales 112

Pharmaceutical Technology

FEBRUARY 8, 2023

On February 7, at a town hall organised to discuss clinical trial designs for gene therapies, FDA experts pushed pharma players to look for ways to establish clinical effectiveness despite the challenges in recruiting patients with rare diseases.

FDA 105

FDA Patients Pharmacology Pharmaceutical 105

Clarivate

FEBRUARY 28, 2023

LHON mutation rate variability affects therapeutic efficacy Most LHON patients carry one of three pathogenic mitochondrial DNA mutations (11778G>A [ND4], 14484T>C [ND6] and 3460G>A [ND1]) known as primary LHON mutations. We identified patients with an LHON diagnosis using ICD-10 and ICD-9 codes H47.2 The Clarivate U.S.

Prescription 98

Prescription Patients Pharmacology Healthcare 98

European Pharmaceutical Review

JULY 27, 2023

Pharmacological therapies mainly address symptoms and unfortunately a significant number of patients do not respond adequately, progressing to congestive heart failure and eventually needing a heart transplant. As this is an autologous therapy, there is a lot of patient-to-patient variability. 1 Furthermore, there are 63.3

Pharmacology 98

Pharmacology Manufacturing Leads Patients 98