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The availability of oral chemotherapy treatments would provide stomach cancer patients with the option of more efficacious drugs with improved tolerability in a more convenient dosage format” The poor clinical outcomes of stomach cancer make it a key target for drug development. New hope for stomach cancer patients.
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. “Delaying drug release and delivering oral dosage forms to the colon is challenging, so T21 offers a promising new option for ulcerative colitis patients by providing site-specific drug delivery and localised drug effect, mitigating potential sideeffects from systemic exposure.
Spectrum filed for accelerated approval of poziotinib as a second-line treatment for patients with HER2 exon 20 insertion-mutated, non-small cell lung cancer (NSCLC), but the FDA was unconvinced by the phase 2 data presented in support of the drug.
Slow-release formulations were a popular choice for manufacturers, as these varieties reduce the traditional dosage frequency for patients, who only need to take these medications say, once a week. This is especially beneficial as a way of decreasing potential sideeffects.
Patients with end-stage renal disease (ESRD) who are on dialysis often need to be treated with anticoagulants to prevent blood clots, but as a result, can experience bleeding sideeffects. Now, Ionis and Bayer think they have a new drug that could sidestep that risk.
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They also include many of the common “exclusions” in RCTs, such as pregnant women, children, the elderly and patients on multiple medications. million patients were registered with GP practices in England, which hold health information about each person “from the cradle to the grave”. As of October 2023, 62.93 EMA/95098/2010.
Cancer-associated fibroblasts, and their effects of the immune activity in the tumour, are considered one of the main reasons why around four out of five patients do not benefit from immunotherapies such as checkpoint inhibitors. For the 28 patients who received only pembrolizumab, the OS was 58 percent. 2015; 23(5):358–74.
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It has boosted anti-tumour research by 60% since 2005, at a cost of $1.6bn, in the hope of increasing the share of company sales attributed to cancer drugs from the current level of 5% “There are a lot of patients that are suffering,” said Pfizer chief executive Jeffrey Kindler.
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Back in 2015, the influencer-of-influencers, Kim Kardashian, was slammed for failing to mention the potential sideeffects of an anti-nausea drug, leading to the US FDA getting involved. Despite the slap on the wrist, the campaign was highly effective and there is no sign of this approach going away. Connecting Peers.
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